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| 1 | β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas:role in the regulation of response to somatostatin analogue treatment in patients with acromegaly显示文摘Recent in vitro studies highlighted G protein-coupled receptor kinase(GRK)2 andβ-arrestins as important players in driving somatostatin receptor(SSTR)desensitization and trafficking.Our aim was to characterize GRK2 andβ-arrestins expression in different pituitary adenomas and to investigate their potential role in the response to somatostatin analog(SSA)treatment in GHsecreting adenomas(GHomas).We evaluated mRNA expression of multiple SSTRs,GRK2,β-arrestin 1,andβ-arrestin 2 in 41pituitary adenomas(31 GHomas,6 nonfunctioning[NFPAs],and 4 prolactinomas[PRLomas]).Within the GHomas group,mRNA data were correlated with the in vivo response to an acute octreotide test and with the GH-lowering effect of SSA in cultured primary cells.β-Arrestin 1 expression was low in all 3 adenoma histotypes.However,its expression was significantly lower in GHomas | Gatto F Feelders R van der Pas R Kros JM Dogan F van Koetsveld PM van der Lelij AJ Neggers SJ Minuto F de Herder W Lamberts SW Ferone D Hofland LJ | 2013 | 中国神经肿瘤杂志2013，11，4： | 2 |
| 2 | Cyclic histomorphological changes in the ovary of mudfish, Labeo capensis显示文摘 | van Vuren J H J Vermaak J F | 1988 | Aquac1988，72，： | 1 |
| 3 | Transcriptional gene silencing and promoter methylation triggered by double stranded RNA 显示文摘 | Aufsatz W van der Winden J Matzke M A Matzke A J M | 2000 | EMBO J2000，19，： | 1 |
| 4 | The Influence of Crosslinkage on the Distribution Cofficients and Anion Exchange Behavior of Some Elements in Hydrochloric Acid显示文摘 | Van der Walt T N Strelow F W E Verheij R | 1985 | Solvent Extr Ion Exc1985，3，： | 1 |
| 5 | Work- flow mining A survey of issues and approaehes显示文摘 | van der Aalst W M P van Dongen B F Herbst J | 2003 | Data and Know ledge Engineering2003，47，2： | 1 |
| 6 | Soil Moisture Retrieval Using Thermal Inertia, Determined with Visible and Thermal Spaceborne Data, Validated for Eu ropean Forest 显示文摘 | Verstraeten W W Veroustraete F van der Sande C J | 2006 | Remote Sensing of Environment2006，101，： | 1 |
| 7 | Visualization of differential gene expression using a novel method of RNA fingerprinting based on AFLP:Analysis of gene expression during potato tuber development显示文摘 | Bachem C W B van der Hoeven R S de Bruijn S M Vreugdenhil D Zabeau M Visser R G F | 1996 | Plant J1996，9，： | 1 |
| 8 | Algorithmic statistical process control: Concepts and an application 显示文摘 | Van Der Wiel S A Tucker W T Fahin F W Doga- naksoy N | 1992 | Technometrics1992，34，3： | 1 |
| 9 | Solving topological constraints for declarative family of objects 显示文摘 | Van der MEIDEN H A BRONSVOORT W F | 2007 | Computer Aided Design2007，39，8： | 1 |
| 10 | Analysis of 8000 hospital admissions for acute poisoning in a rural area of Sri Lanlka显示文摘 | VAN DER HOEK W KONRADSEN F | 2006 | Clin Toxicol (Phila)2006，44，： | 1 |
| 11 | Evidence based selection of housekeeping genes显示文摘 | de Jonge H J Fehrmann R S de Bont E S Hofstra R M Gerbens F Kamps W A de Vries E G van der Zee A G te Meerman G J ter Elst A | | 0，，： | 1 |
| 12 | Genetic basis forpulse crop improvement:Collection,preservation and genetic variation in relation to needed traits显示文摘 | VAN DER MAESEN L J G KAISER W J MARX F A | 1988 | Current plant and biotechnology in agriculture1988，5，： | 1 |
| 13 | Glutathione-S-transferase and hydrolytic activity in a tetrachlorvinphos-resistance strain of house fly and their influence on resistance 显示文摘 | Oppenoorth F J van der Pas L J R Houx N W H | 1979 | Pestic Biochem Physiol1979，11，： | 1 |
| 14 | Methane emission from tid- al freshwater marshes显示文摘 | Van der Nat F J W A Middelburg J J | 2000 | Biogeochemistry2000，49，： | 1 |
| 15 | Incidence of and preoperative predictors for delirium after cardiac surgery显示文摘 | Rose C van der Mast Walter W van den Broek Durk Fekkes Lolke Pepplinkhuizen J.Dik F Habbema | 1999 | Journal of Psychosomatic Research1999，，5： | 1 |
| 16 | Workflow Mining : A Survey of Issuesand Approaches 显示文摘 | W M P VAN DER AALST B F VAN DONGEN JHERBST | 2003 | Data and Knowledge Engineer-ing2003，47，2： | 1 |
| 17 | Analysis of 8000 hospital admissions for acute poisoning in a rural area of Sri Lanka显示文摘 | Van der Hoek W Konradsen F | 2006 | Clin Toxicol ( Phila )2006，44，3： | 1 |
| 18 | Infliximab and methotrexate in the treatment of rheumatoid arthritis显示文摘 | LIPSKY P E van der HEIJDE D M F M ST-CLAIR E W | 2000 | N Engl J Med2000，343，22： | 1 |
| 19 | Temporal correlation of blood scattering signals in vivo from radiofrequency intravascular ultrasound 显示文摘 | Li W van der Steen A F W Lancee C T | 1996 | Ultrasound Med Biology1996，22，5： | 1 |
| 20 | Visualization of differential gene expression using a novel method of RNA fingerprinting based on AFLP:analysis of gene expression during potato tuber development显示文摘 | BACHEM C W B VAN DER HOEVEN R S DE BRUIJN S M VREUGDENHIL D ZABEAU M VISSER R G F | 1996 | Plant Journal1996，9，5： | 1 |
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