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| 1 | Local icariin application enhanced periodontal tissue regeneration and relieved local inflammation in a minipig model of periodontitis显示文摘Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis. | Xiuli Zhang Nannan Han Guoqing Li Haoqing Yang Yangyang Cao Zhipeng Fan Fengqiu Zhang | 2018 | International Journal of Oral Science2018，10，3： | 9 |
| 2 | Sensitivity of Medium-Range Weather Forecasts to the Use of Reference Atmosphere显示文摘In this paper, the authors develop the earlier work of Chen Jiabin et al. (1986). In order to reduce spectral truncation errors, the reference atmosphere has been introduced in ECMWF model, and the spectrally-represented variables, temperature, geopotential height and orography, are replaced by their deviations from the reference atmosphere. Two modified semi- implicit schemes have been proposed to alleviate the computational instability due to the introduction of reference atmosphere. Concerning the deviation of surface geopotential height from reference atmosphere, an exact computational formulation has been used instead of the approximate one in the earlier work. To re duce aliasing errors in the computations of the deviation of the surface geopotential height, a spectral fit has been used slightly to modify the original Gaussian grid-point values of orography.A series of experiments has been performed in order to assess the impact of the reference atmosphere on ECMWF medium- range forecasts at the | 陈嘉滨 A.J.Simmons | 1990 | Advances in Atmospheric Sciences1990，7，3： | 2 |
| 3 | STUDY ON PREVENTIVE AND CURATIVE EFFECTS OF LIU WEI DI HUANG TANG ON TUMORS显示文摘Liu Wei Di Huang Tang (LWDHT), a Chinese Prescription for strengthening the body re-sistance, restoring the normal functions of the body to consolidate the constitution, and nour-ishing and invigorating the kidney yin, has been used to prevent and treat severe hypeplasiaof esophageal epithelium for many years. The results of this experiment show that LWDHTcan increase markedly the number of lymphocytes, mainly T lymphocytes, in tumor--bearingmice. Free--flow electrophoresis shows that in tumor--bearing mice the electrophoretic char-acteristics of T lymphocytes are changed, i.e., reduction of the number of T lymphocyteswith a higher electrophoretic rate, but LWDHT can alleviate this disorder. Study on the cellmembrane fluidity of carcinoma cells in EAC mice demonstrates that LWDHT can decreasethe cell membrane fluidity. suggesting that it can inhibit division of carcinoma | 蔡波文 姜廷良 | 1994 | Journal of Traditional Chinese Medicine1994，14，3： | 2 |
| 4 | Effects of electroacupuncture at Zusanli(ST 36) on the expressions of small intestinal occludin protein and nuclear factor kappa-B in rats with severe acute pancreatitis显示文摘Objective To explore the mechanism of electroacupuncture at Zusanli(ST 36)on regulation of intestinal inflammatory reaction in rats with acute pancreatitis.Methods Fifty-four SD rats were randomly divided into a severe acute pancreatitis(SAP)group,an electroacupuncture(EA)group and a sham-operation(SO)group,18 cases in each group.3.5%sodium cholate was | 薜奇明 | 2014 | China Medical Abstracts(Internal Medicine)2014，31，2： | 0 |
| 5 | Renoprotective effect of transforming growth factor beta activator kinase 1 inhibitor in diabetic db / db mice and its mechanism显示文摘Objective To investigate the renoprotective effect of transforming growth factor beta activator kinase 1(TAK1)inhibitor 5Z-7-oxozeaenol(OZ)in diabetic db/db mice and the mechanism.Methods Twenty-four male db/db mice were randomly divided into two groups:db/db mice(db/db,n=12)and db/db mice with 5Z-7-ox- | 李媛媛 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，1： | 0 |
| 6 | PREVENTION OF ATHEROSCLEROTIC ARTERIAL STENOSIS AND RESTENOSIS AFTER ANGIOPLASTY WITH ANDROGRAPHIS PANICULATA NEES AND FISH OIL EXPERIMENTAL STUDIES OF EFFECTS AND MECHANISMS显示文摘Restenosis rate after coronary angioplasty has been up to 30%-40%. To solve this problem, we studied the effects of Andrographis Paniculata Nees (APN) and fish oil (FO, ω3 polyunsaturated fatty acids over 70%) on atheroselerotic stenosis and restenosis after experimental angioplasty and the relevant mechanisms of APN and FO. Preliminary results showed that APN can significantly alleviate atherosclerotic iliac artery stenosis induced by both decndothelialization and high cholesterol diet (HCD) and restenosis following angioplasty in rabbits. FO showed the same but milder effects than APN did. Both APN and FO significantly inhibited blood monocytes to secrete growth factors in vivo. Ca++ -ATPase activity of cell membrane of atherosclerotic rabbits was significantly decreased, while APN or FO, especially the former alleviated this reduction. Refined extract of APN significantly decreased in vitro resting platelet [Ca++]i and in vivo the resting and thrombin-stimulated platelet [Ca++]i after | 汪道文 赵华月 | 1994 | Chinese Medical Journal1994，，6： | 0 |
| 7 | Protective effect of glucagon-like peptide-1analogue on cardiomyocytes injury induced by hypoxia/reoxygenation显示文摘Objective To investigate the effect of glucagon-like peptide-1(GLP-1)receptor agonist liraglutide on hypoxia/reoxygenation(H/R)-induced cardiomyocytes death under high glucose condition and the potential mechanisms.Methods H9C2 cardiomyocytes were divided into4 groups:normal glucose(N,5 mmol/L),high glucose(G,20 mmol/L),high glucose in combination with lira- | 刘玫梅 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，2： | 0 |
| 8 | Develop electric vehicles to alleviate city pollution显示文摘As main transportation and communication facilities,automo-biles contribute much convenience for people all over the world.However,they also bring about serious problem of pollution,espe-cially in urban areas where people are jeopardized in health by theheavy noise and the toxic substances in the exhaust gas from them.Early in 1966,air pollution investigation made by USA pointed outthat 61% of total air pollution originated from automobiles.In 1981,West Germany studied and analysed the detrimental substancesexhausted from sedans,trucks and buses per kilometer travel dis-tance,as shown in the following table: | Lai Jian Vice President of China Electrotechnical Society | 1992 | Electricity1992，，4： | 0 |
| 9 | Effects of pretreatment with recombinant human B-type natriuretic peptide on infarct size in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention显示文摘Objective To investigate whether the administration of recombinant human B-type natriuretic peptide(rh BNP)before primary percutaneous coronary intervention(PCI)could further limit the infract size,improve left ventricular function,and alleviate cardiac dilation in patients with acute ST-segnent elevation myocardial infarc- | 李世强 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，1： | 0 |
| 10 | Clinical effect of edaravone on serum superoxide dismutase and malondialdehyde levels in elderly transient ischemic attack显示文摘Objective To investigate the clinical effect of Edaravone on transient ischemic attack and serum superoxide dismutase and malondialdehyde levels in the elderly.Methods Ninety eight cases with transient ischemic attack treated in our hospital were chosen as the objects, | 王欣 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，1： | 0 |
| 11 | DRUGS FOR CLEARING HEAT OF DEFICIENCY TYPE—Selected from A Practical English—Chinese Library of Traditional Chinese Medicine显示文摘Drugs whose principal effects are toremove the stagnation of sputum are calledexpectorants;drugs which alleviate coughand asthma are called antitussives andantiasthmatics rospectively.As mostexpectorants also have the effect of relievingcough and asthma,and antitussives andantiasthmatics have the effect of resolvingsputum,they are generally referred to | 张恩勤 曲京峰 张玉玺 赵华英 | 1992 | Journal of Traditional Chinese Medicine1992，12，3： | 0 |
| 12 | CLINICAL OBSERVATIONS ON THE ANTI-REJECTION EFFECT OF CHINESE DRUGS IN HOMOGRAFTING OF PANCREATIC ISLETS显示文摘The incidence of diabetes mellitus hasbeen increasing recently with the chroniccomplications seriously threatening the con-dition of the patients.Investigations both inChina and abroad show pancreatictransplantation to be an ideal therapy forType Ⅰ diabetics.On the basis of successfulculture of human pancreatic cells in ourhospital in January 1990,clinical observa- | 潘汝瑾 汪隽芳 | 1992 | Journal of Traditional Chinese Medicine1992，12，2： | 0 |
| 13 | The Ways to Alleviate the Job Stress of College English Teacher显示文摘This paper intends to explore several possible ways to alleviate the job stress of College English teachers from different perspectives: society, college and teachers themselves. | 沈文娟 付强 | 2016 | 青春岁月2016，，9： | 0 |
| 14 | 我为何而活显示文摘三种简单却极其强烈的情感主宰着我的生活:对爱的渴望、对知识的追求、对人类痛苦难以承受的怜悯之心。这三种情感,像一阵阵飓风一样,任意地将我吹得飘来荡去,越过痛苦的海洋,抵达绝望的彼岸。我寻找爱,首先。 | 伯兰特·罗素 | 2008 | 读与写(高中版)2008，0，Z2： | 0 |
| 15 | Reduce Tax and Alleviate the Burden显示文摘‘Tax reduction’must be one of the key words of the Chinese economy in 2018,during which various preferential tax policies were successively issued and tax-cut bonuses are continuously released.Since the beginning of the year,China has set a target of RMB 1.1 trillion in tax reductions throughout the year.In the second half of 2018,incremental policies were introduced.It is estimated that the annual economic burden will be reduced by more than RMB 1.3 trillion in 2018. | Sophie Li | 2019 | China's Foreign Trade2019，，1： | 0 |
| 16 | Influence of SLYWG on malignant tumor ascites显示文摘Objective To search the effect of Chinese traditional medicine 'Shang Lu Yu Wang Gao'(SLYWG)on the ascites induced by tumor,and its mechanism.Methods The tumor ascites model and diuretic experiments were introduced to evaluate the effect of SLYWG.Physical characteristics,the tumor cell counting,volume of the ascites,protein content in ascites,the characters of ascites,the life duration of S180 tumor bearing animals as the indexes of evaluation.the diurtic experiments were performed on rats nad rabbits,the osmotic pressure,K+,Na+,Cl-,Ca2+ and pH in urine were determined.Results The inhibitions to ascites of SLYWG were displayed in three dosage(30 g·kg-1,15 g·kg-1 and 7.5 g·kg-1).Ascites caused by tumor was significantly inhibited by the local administration of SLYWG.The increase of mice ascites was slow down,the content of ALB and the TP in ascites were decreased,the surviving time of mice was extended.SLYWG had remarkable diuresis effect on the rats and rabbits,it could reduce the osmotic pressure of urine,decrease the exclude of K+ but had no effect on the Na+,Cl-,Ca2+ and pH in urine.Conclusions Tumor ascites was significantly inhibited by the ventral administration of SLYWG.SLYWG had diuretic effect in rats and rabbits,it reduced the osmotic pressure of urine,decrease the exclude of K+ but had no effect on Na+,Cl-,Ca2+ and pH of urine. | YANG Tian,XU Feng,WU Tian-yu(Shenyang Pharmaceutical University,Shenyang 110016,China) | 2008 | 沈阳药科大学学报2008，25，S1： | 0 |
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