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| 1 | 为什么到手的金牌会“飞走”:竞赛中“Choking”现象显示文摘'Choking'定义为,习惯的运动执行过程发生衰变的现象.其现象主要发生在比赛的关键时刻,或重大的赛事中.本文概述竞赛中的'Choking'现象及有关的定义,并进一步讨论有关的理论和研究中存在的问题.运动心理学家认为,'Choking'机制与运动焦虑有直接的联系.而社会心理学家认为,'Choking'的机制是,由于运动员有意识地控制运动过程,导致运动技术发生改变.理论上的分歧,使心理学家很难为运动员提出一个行之有效地预防'Choking'的方案.文章认为,当前的'Choking'理论过于简单地解释'Choking'现象,导致了实践中出现的矛盾.在综述这些问题的基础上,文章进一步讨论了一个'Choking'理论的'综合模式'.该理论模式强调多因素原则.在压力条件下,分析'Choking'机制应考虑任务特征和技术水平的因素.文章根据这一理论模式,建议运动员在比赛中,应分析具体情况,选择一个适合的应付压力的策略,是可以减少竞赛中'Choking'现象的.最后,文章建议了3个今后研究的方向. | 王进 | 2003 | 心理学报2003，35，2： | 51 |
| 2 | Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy显示文摘AIM:To evaluate the effect of low central venous pressure(LCVP)on blood loss and blood transfusion in patients undergoing hepatectomy.METHODS:Electronic databases and bibliography lists were searched for potential articles.A meta-analysis of all randomized controlled trials(RCTs)investigating LCVP in hepatectomy was performed.The following three outcomes were analyzed:blood loss,blood transfusion and duration of operation.RESULTS:Five RCTs including 283 patients were assessed.Meta-analysis showed that blood loss in the LCVP group was significantly less than that in the control group(MD=-391.95,95%CI:-559.35--224.56,P<0.00001).In addition,blood transfusion in the LCVP group was also significantly less than that in the control group(MD=-246.87,95%CI:-427.06--66.69,P=0.007).The duration of operation in the LCVP group was significantly shorter than that in the control group(MD=-18.89,95%CI:-35.18--2.59,P=0.02).Most studies found no significant difference in renal and liver function between the two groups.CONCLUSION:Controlled LCVP is a simple and effective technique to reduce blood loss and blood transfusion during liver resection,and appears to have no detrimental effects on liver and renal function. | Zhi Li Yu-Ming Sun Fei-Xiang Wu Li-Qun Yang Zhi-Jie Lu Wei-Feng Yu | 2014 | World Journal of Gastroenterology2014，20，1： | 60 |
| 3 | Prognostic value of intracranial pressure monitoring for the management of hypertensive intracerebral hemorrhage following minimally invasive surgery显示文摘BACKGROUND:The incidence of hypertensive intracerebral hemorrhage(HICH)has been increasing during the recent years in low-and middle-income countries.With high mortality and morbidity rates,it brings huge burden to the families.It lacks evidence regarding the application of intracranial pressure(ICP)monitoring in HICH.In the current study,the authors aimed to evaluate whether ICP monitoring could make any difference on the prognosis of HICH patients after minimally invasive surgery.METHODS:A retrospective review of 116 HICH patients admitted to the Second Affiliated Hospital of Zhejiang University School of Medicine,between 2014 and 2016,was performed.The effects of ICP monitoring on 6-month mortality and favorable outcomes were evaluated by univariate and logistic regression analysis.RESULTS:ICP monitors were inserted into 50 patients.Patients with ICP monitoring had a significantly better outcome(P<0.05).The average in-hospital duration in patients with ICP monitoring was shorter than that in the patients without ICP monitoring(16.68 days vs.20.47 days,P<0.05).Mortality rates between ICP monitoring and no ICP monitoring did not differ significantly(16.0%vs.15.1%,P=0.901).On univariate analysis,age,Glasgow Coma Scale(GCS)on admission and presence of ICP monitor were independent predictors of 6-month favorable outcomes.CONCLUSION:ICP monitoring is associated with a better 6-month functional outcome compared with no ICP monitoring.Future study is still needed to confirm our results and elucidate which subgroup of HICH patients will benefit most from the minimally invasive surgical intervention and ICP monitoring. | Xiao-ru Che Yong-jie Wang Hai-yan Zheng | 2020 | World Journal of Emergency Medicine2020，11，3： | 41 |
| 4 | Ultrahigh pressure (>7 GPa) gneissic K-feldspar (-bearing) garnet clinopyroxenite in the Altyn Tagh, NW China: Evi- dence from clinopyroxene exsolution in garnet显示文摘The exsolution of clinopyroxene and rutile in coarse-grain garnet is found in the gneissic K-feldspar(-bearing) garnet clinopyroxenite from Yinggelisayi in the Altyn Tagh, NW China. The maximum content of the exsolved clinopyroxene in the garnet is up to >5% by volume. The reconstructed precursor garnet (Grt1) before exsolution has a maximum Si content of 3.061 per formula uint, being of supersilicic or majoritic garnet. The peak-stage metamorphic pressure of >7 GPa is estimated using the geobarometer for volume percentage of exsolved pyroxene in garnet and the Si-(Al+Cr) geobarometer for majoritic garnet, and the temperature of about 1000℃ using the ternary alkali-feldspar geothermometer and the experimental data of ilmen- ite-magnetite solid solution. The protoliths of the rocks are intra-plate basic and intermediate ig- neous rocks, of which the geochemical features indicate that they are probably the products of the evolution of basic magma deriving from the continental lithosphere mantle. The rocks are in outcrops associated with ultrahigh pressure garnet-bearing lherzolite and ultrahigh pressure garnet granitoid gneiss. All of these data suggest that the ultrahigh pressure metamorphic rocks in the Altyn Tagh are the products of deep-subduction of the continental crust, and such deep- subduction probably reaches to >200 km in depth. This may provide new evidence for further discussion of the dynamic mechanism of the formation and evolvement of the Altyn Tagh and the other collision orogenic belts in western China. | LIU Liang1,3, CHEN Danling1, ZHANG Anda1, SUN Yong1, WANG Yan1, YANG Jiaxi1,2 & LUO Jinhai1 1. Key Laboratory of Continental Dynamics of the Ministry of Education of China, Northwest University, Xi’an 710069, China 2. College of Earth Science and Land Resources, Chang’an University, Xi’an 710054, China 3. The Laboratory of Orogen and Basin of the Ministry of Education, Peking University, Beijing 100871, China | 2005 | Science China Earth Sciences2005，48，7： | 38 |
| 5 | Use of portal pressure studies in the management of variceal haemorrhage显示文摘Portal hypertension occurs as a complication of liver cirrhosis and complications such as variceal bleeding lead to significant demands on resources. Endoscopy is the gold standard method for screening cirrhotic patients however universal endoscopic screening may mean a lot of unnecessary procedures as the presence of oesophageal varices is variable hence a large time and cost burden on endoscopy units to carry out both screening and subsequent follow up of variceal bleeds. A less invasive method to identify those at high risk of bleeding would allow earlier prophylactic measures to be applied. Hepatic venous pressure gradient (HVPG) is an acceptable indirect measurement of portal hypertension and predictor of the complications of portal hypertension in adult cirrhotics. Varices develop at a HVPG of 10-12 mmHg with the appearance of other complications with HPVG > 12 mmHg. Variceal bleeding does not occur in pressures under 12 mmHg. HPVG > 20 mmHg measured early after admission is a significant prognostic indicator of failure to control bleeding varices, indeed early transjugular intrahepatic portosystemic shunt (TIPS) in such circumstances reduces mortality significantly. HVPG can be used to identify responders to medical therapy. Patients who do not achieve the suggested reduction targets in HVPG have a high risk of rebleeding despite endoscopic ligation and may not derive significant overall mortality benefit from endoscopic intervention alone, ultimately requiring TIPS or liver transplantation. Early HVPG measurements following a variceal bleed can help to identify those at risk of treatment failure who may benefit from early intervention with TIPS. Therefore, we suggest using HVPG measurement as the investigation of choice in those with confirmed cirrhosis in place of endoscopy for intitial variceal screening and, where indicated, a trial of B-blockade, either intravenously during the initial pressure study with assessment of response or oral therapy with repeat HVPG six weeks later. In those with elevated pressures, primary medical prophylaxis could be commenced with subsequent close monitoring of HVPG thus negating the need for endoscopy at this point. All patients presenting with variceal haemorrhage should undergo HVPG measurement and those with a gradient greater than 20 mmHg should be considered for early TIPS. By introducing portal pressure studies into a management algorithm for variceal bleeding, the number of endoscopies required for further intervention and follow up can be reduced leading to significant savings in terms of cost and demand on resources. | Jennifer Addley Tony CK Tham William Jonathan Cash | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，7： | 37 |
| 6 | 藏北羌塘中部绒玛地区蓝片岩岩石学、矿物学和^(40)Ar/^(39)Ar年代学显示文摘藏北羌塘中部沿龙木错-双湖-线出露一条低温高压变质带,目前已有多处蓝片岩的报道。然而,除冈玛错地区产有典型的蓝闪石外,多数地区并没有典型蓝闪石的报道。绒玛蓝片岩位于羌塘中部高压变质带的中段,是该带中规模最大、保存最好的蓝片岩,对蓝片岩进行了详细的岩石学和矿物学研究,钠质角闪石主要为蓝闪石、青铝闪石、钠闪石和镁钠闪石。对蓝片岩中蓝闪石和多硅白云母进行了^(40)Ar/^(39)Ar定年,获得了227.3±3.8Ma和215±1.5Ma的坪年龄,分别代表蓝片岩快速俯冲消减和俯冲作用结束开始折返抬升的时代。绒玛蓝片岩岩石学、矿物学和^(40)Ar/^(39)Ar年代学研究为羌塘中部高压变质带的研究提供了新的资料。 | 翟庆国 李才 王军 陈文 张彦 | 2009 | 岩石学报2009，25，9： | 38 |
| 7 | Influence of tectonic stress on coalification:Stress degradation mechanism and stress polycondensation mechanism显示文摘The function of pressure for coalification is a long-term controversial issue, and the main cause is that the strata pressure and the tectonic stress were confused, which are two different actions of 'pres-sure' . The former benefits the physical coalification but retards the chemical coalification, whereas the latter may not only affect the physical structure of coal but also promote its chemical composition changes. In accordance with the organic molecule evolution of coal, there are two kinds of basic mechanisms of the influence of the tectonic stress on the chemical coalification: the tectonic stress degradation and the tectonic stress polycondensation. The stress degradation mechanism is a process of that, when the tectonic stress acted on the large molecule of coal in the form of mechanical force or kinetic energy, some chemical bonds of low decomposed energy, such as aliphatic side-chain and oxygenic functional groups, were broken up and then were degraded into free radicals of less mo-lecular weight, and finally escaped from coal in the form of liquid organic matter (hydrocarbon). The stress polycondensation is considered that, under the control of the anisotropic tectonic stress, the condensed aromatic nucleus trend to be parallel arranged and to be enhanced through rotating or displacing of aromatic rings, the basic structural unit of coal (BSU) increases by directional develop-ment and preferential stack. X-ray diffraction (XRD), Fourier transformation infrared microspectroscopy (FTIR), and rock pyrolysis analysis (Rock-eval) were employed to study the deformed coal series and the non-deformed coal series. The results showed that, compared with the non-deformed coal, the de-formed coal exhibits particular characteristics: weaker aliphatic absorbance peak and stronger aro-matic absorbance peak, lower pyrolysed hydrocarbon yield, and more increscent BSU. The concepts of stress degradation mechanism and stress polycondensation mechanism presented here would not deny the dominant function of the temperature in coalification, but emphasize the 'catalysis' of the tectonic stress in coalification. | CAO DaiYong LI XiaoMing ZHANG ShouRen | 2007 | Science China Earth Sciences2007，50，1： | 36 |
| 8 | Study of the High Pressure Metamorphic Blueschist and Its Late Proterozoic Age in the Eastern Jiangnan Belt显示文摘Several blueschist outcrops, specially glaucophane-bearing ones, were found in Dexing, eastern Jiangnan belt. The latest researches suggest that the blueschists distributed in the Late Proterozoic ophiolite melange blocks of the northeastern Jiangxi fault zone between the Jiuling tectonic region and the Huaiyu tectonic region of volcanic are that is located near the frontier of Jiangxi, Zhejiang and Anhui provinces (Fig. 1). | 舒良树 周国庆 施央申 殷俊 | 1994 | Chinese Science Bulletin1994，39，14： | 32 |
| 9 | WJD 5^(th) Anniversary Special Issues(2): Type 2 diabetes Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength?显示文摘Diabetes mellitus is a chronic condition that occurs when the body cannot produce enough or effectively use of insulin.Compared with individuals without diabetes,patients with type 2 diabetes mellitus have a considerably higher risk of cardiovascular morbidity and mortality,and are disproportionately affected by cardiovascular disease.Most of this excess risk is it associated with an augmented prevalence of well-known risk factors such as hypertension,dyslipidaemia and obesity in these patients.However the improved cardiovascular disease in type 2 diabetes mellitus patients can not be attributed solely to the higher prevalence of traditional risk factors.Therefore other non-traditional risk factors may be important in people with type 2 diabetes mellitus.Cardiovascular disease is increased in type 2 diabetes mellitus subjects due to a complex combination of various traditional and non-traditional risk factors that have an important role to play in the beginning and the evolution of atherosclerosis over its long natural history from endothelial function to clinical events.Many of these risk factors could be common history for both di-abetes mellitus and cardiovascular disease,reinforcing the postulate that both disorders come independently from'common soil'.The objective of this review is to highlight the weight of traditional and non-traditional risk factors for cardiovascular disease in the setting of type 2 diabetes mellitus and discuss their position in the pathogenesis of the excess cardiovascular disease mortality and morbidity in these patients. | Iciar Martín-Timón Cristina Sevillano-Collantes Amparo Segura-Galindo Francisco Javier del Caizo-Gómez | 2014 | World Journal of Diabetes2014，5，4： | 32 |
| 10 | EXPERIMENTAL STUDIES ON THE ROLE OF PLANKTIVOROUS FISHES IN THE ELIMINATION OF MICROCYSTIS BLOOM FROM DONGHU LAKE USING ENCLOSURE METHOD显示文摘The hypertrophic subtropic Donghu Lake’s dense water bloom(of mainly Microcystis Anaabaena andOscillatoria)that occurred annually from the beginning of the 1970s, has disappeared since 1985. The infiuenceof planktivorous fishes (silver and bighead carps) on the water bloom was studied for three years usingthe enclosure method. The enclosures stocked densely with bighead and/or silver carp were free of waterbloom during the experimental period. The water bloom that appeared in the fish-free enclosures was completelyeliminated in 10-20 days by introduction of silver and/or bighead carp(grass carp was not effectivein controlling water bloom).This study showed clearly that grazing pressure by planktivorous fishes is a keyfactor in eliminating water bloom from the lake. | 谢平 | 1996 | Chinese Journal of Oceanology and Limnology1996，14，3： | 32 |
| 11 | Management of negative pressure wound therapy in the treatment of diabetic foot ulcers显示文摘Diabetic foot(DF) is a common complication of diabetes and the first cause of hospital admission in diabetic patients. In recent years several guidelines have been proposed to reinforce the the management of DF with a notable increase in diabetes knowledge and an overall reduction of amputations. Significant improvements have been reached in the treatment of diabetic foot ulcers(DFUs) and nowadays clinicians have several advanced medications to apply for the best local therapy. Among these, negative pressure wound therapy(NPWT) is a useful adjunct in the management of chronic and complex wounds to promote healing and wound bed preparation for surgical procedures such as skin grafts and flap surgery. NPWT has shown remarkable results although its mechanisms of action are not completely understood. In this paper, we offer a complete overview of this medication and its implication in the clinical setting. We have examined literature related to NPWT concerning human, animal and in vitro studies, and we have summarized why, when and how we can use NPWT to treat DFUs. Further we have associated our clinical experience to scientific evidence in the field of diabetic foot to identify a defined strategy that could guide clinician in the use of NPWT approaching to DFUs. | Marco Meloni Valentina Izzo Erika Vainieri Laura Giurato Valeria Ruotolo Luigi Uccioli | 2015 | World Journal of Orthopedics2015，6，4： | 33 |
| 12 | A NUMERICAL STUDY ON THE FORMATION AND DEVELOPMENT OF ISLAND-INDUCED CYCLONE AND ITS IMPACT ON TYPHOON STRUCTURE CHANGE AND MOTION显示文摘In this paper,the impact of the Taiwan Island topography on the structure change and motion ofTyphoon Dot(9017)during its crossing the Taiwan Island is studied with a modified version of aJMA operational regional model(Japan spectral model,JSM).A series of sensitivity experiments areconducted to detect the forming and developing mechanism of an island-induced cyclone.Results showthat lee side low pressure center plays a very important role in the formation of the induced-cyclonewhile a typhoon is approaching a large island with high mountains.The position and intensity of theinduced cyclone is sensitive to the height and location of island mountain,intensity of TC and under-lying surface topography distribution as well.A preliminary formation criterion of the island-inducedcyclone is obtained. | 孟智勇 永田雅 陈联寿 | 1996 | Acta meteorologica Sinica1996，10，4： | 24 |
| 13 | Research on the mechanics of underwater supersonic gas jets显示文摘An experimental research was carried out to study the fluid mechanics of underwater supersonic gas jets. High pressure air was injected into a water tank through converging-diverging nozzles (Laval nozzles). The jets were operated at different conditions of over-, full- and under-expansions. The jet sequences were visualized using a CCD camera. It was found that the injection of supersonic air jets into water is always accompanied by strong flow oscillation, which is related to the phenomenon of shock waves feedback in the gas phase. The shock wave feedback is different from the acoustic feedback when a supersonic gas jet discharges into open air, which causes screech tone. It is a process that the shock waves enclosed in the gas pocket induce a periodic pressure with large amplitude variation in the gas jet. Consequently, the periodic pressure causes the jet oscillation including the large amplitude expansion. Detailed pressure measurements were also conducted to verify the shock wave feedback phenomenon. Three kinds of measuring methods were used, i.e., pressure probe submerged in water, pressure measurements from the side and front walls of the nozzle devices respectively. The results measured by these methods are in a good agreement. They show that every oscillation of the jets causes a sudden increase of pressure and the average frequency of the shock wave feedback is about 5–10 Hz. | SHI HongHui1, WANG BoYi2 & DAI ZhenQing2 1 College of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China 2 State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，3： | 22 |
| 14 | Balloon-occluded transcatheter arterial chemoembolization for hepatocellular carcinoma显示文摘Transcatheter arterial chemoembolization(TACE) is widely accepted as a treatment for patients with hepatocellular carcinoma(HCC) in the intermediate stage according to the Barcelona Clinic Liver Cancer(BCLC) guidelines. Recently, balloon-occluded TACE(B-TACE) was developed in Japan. Despite the lack of a clear definition, B-TACE is generally defined as the infusion of emulsion of chemotherapeutic agents with lipiodol followed by gelatin particles under the occlusion of feeding arteries by a microballoon catheter, which leads to the dense lipiodol emulsion(LE) accumulation in HCC nodules. This phenomenon cannot be explained only by the prevention of proximal migration and leakage of embolization materials; it further involves causing local changes in the hemodynamics of the surrounding occlusion artery and targeted HCC nodules. Balloon-occluded arterial stump pressure plays an important role in the dense LE accumulation in targeted HCC nodules. Although randomized controlled trials comparing the therapeutic effect and the prognosis of B-TACE to those of the other TACE procedures, such as conventional-TACE and drug-eluting beads TACE, are still lacking, B-TACE is thought to be a promising treatment. The purpose of this review is to summarize the mechanism, therapeutic effect, indication, prognosis and complications of BTACE. | Takeshi Hatanaka Hirotaka Arai Satoru Kakizaki | 2018 | World Journal of Hepatology2018，10，7： | 22 |
| 15 | 郯庐断裂带张八岭隆起南段肥东群石榴角闪岩变质P-T演化史对其构造属性的制约显示文摘通过对张八岭隆起南端肥东群中磁铁石榴铁闪石岩的岩相学、矿物成分分析和热力学评价,并结合野外地质填图和共生围岩分析表明,该岩石经历了5期变质作用,展现了顺时针的P-T演化特征,早期阶段表现为近等压升温,晚期阶段为降温降压的过程,其峰期变质平均P-T条件为:524℃和0.49GPa。结合地质背景和郯庐断裂带的演化特征分析,早期过程可能反映的扬子基底所经历的区域变质过程,晚期过程可能是由于郯庐断裂的后期抬升分量所致,不具有造山带的P-T演化特征。对比前人对宿松群的变质演化历史的研究,肥东群和宿松群峰期变质压力差可达0.8GPa,表明两者属于不同变质级别的块体。因而,肥东群和宿松群不能作为被郯庐断裂左行错开的标志层。由此表明,张八岭隆起南段所出露的肥东群变质杂岩,属于扬子板块上的变质基底,郯庐断裂带活动中将其剥露地表,并没有经历过大别造山带的变质作用。 | 石永红 朱光 王道轩 | 2009 | 岩石学报2009，25，12： | 21 |
| 16 | Sm-Nd age dating of high-pressure granulites and amphi-bolite from Sanggan area,North China craton显示文摘The high pressure (HP) metamorphic age has been dated to HP rocks from the Sanggan area, North China craton. We have got garnet+whole rock isochron ages of (1 842±38) Ma for HP granulite, and (1 856± 26) Ma for HP amphibolite. The Sm-Nd whole rock isochron of HP granulites give out an age of (1870±150) Ma with Nd depleted mantle model age of (2402-2 482) Ma. Considering the Nd isotope homogenization during the peak metamorphism of the HP granulite, Sm-Nd closure temperature and the retention of Nd isotopic memory in garnets partially broken down during decompression, all these isochron ages are thought to be HP metamorphic age. Furthermore, we proposed that the HP metamorphism took place at the end of Paleoproterozoic during the large-scale collision and assembly of the North China craton. | Jinghui Guo Mingguo Zhai | 2001 | Chinese Science Bulletin2001，46，2： | 21 |
| 17 | Measures against the adverse impact of natural wind on air-cooled condensers in power plant显示文摘The natural wind plays disadvantageous roles in the operation of air-cooled steam condensers in power plant.It is of use to take various measures against the adverse effect of wind for the performance improvement of air-cooled condensers.Based on representative 2×600 MW direct air-cooled power plant,three ways that can arrange and optimize the flow field of cooling air thus enhance the heat transfer of air-cooled condensers were proposed.The physical and mathematical models of air-cooled condensers with various flow leading measures were presented and the flow and temperature fields of cooling air were obtained by CFD simulation.The back pressures of turbine were calculated for different measures on the basis of the heat transfer model of air-cooled condensers.The results show that the performance of air-cooled condensers is improved thus the back pressure of turbine is lowered to some extent by taking measures against the adverse impact of natural wind. | YANG LiJun,DU XiaoZe & YANG YongPing Key Laboratory of Condition Monitoring and Control for Power Plant Equipment of Ministry of Education of China,North China Electric Power University,Beijing 102206,China | 2010 | Science China(Technological Sciences)2010，53，5： | 21 |
| 18 | Osteopontin: A non-invasive parameter of portal hypertension and prognostic marker of cirrhosis显示文摘AIM: To investigate the relationship between osteopontin plasma concentrations and the severity of portal hypertension and to assess osteopontin prognostic value.METHODS: A cohort of 154 patients with confirmed liver cirrhosis(112 ethylic, 108 men, age 34-72 years)were enrolled in the study. Hepatic venous pressure gradient(HVPG) measurement and laboratory and ultrasound examinations were carried out for all patients. HVPG was measured using a standard catheterization method with the balloon wedge technique. Osteopontin was measured using the enzyme-linked immunosorbent assay(ELISA) method in plasma. Patients were followed up with a specific focus on mortality. The control group consisted of 137 healthy age- and sex- matched individuals.RESULTS: The mean value of HVPG was 16.18 ± 5.6 mm Hg. Compared to controls, the plasma levels of osteopontin in cirrhotic patients were significantly higher(P < 0.001). The plasma levels of osteopontin were positively related to HVPG(P = 0.0022, r = 0.25) and differed among the individual Child-Pugh groups of patients. The cut-off value of 80 ng/m L osteopontin distinguished patients with significant portal hypertension(HVPG above 10 mm Hg) at 75% sensitivity and 63% specificity. The mean follow-up of patients was 3.7 ± 2.6 years. The probability of cumulative survival was 39% for patients with HVPG > 10 mm Hg and 65% for those with HVPG ≤ 10 mm Hg(P = 0.0086, odds ratio(OR), 2.92, 95% confidence interval(CI): 1.09-7.76). Osteopontin showed a similar prognostic value to HVPG. Patients with osteopontin values above 80 ng/m L had significantly lower cumulative survival compared to those with osteopontin ≤ 80 ng/m L(37% vs 56%, P = 0.00035; OR = 2.23, 95%CI: 1.06-4.68).CONCLUSION: Osteopontin is a non-invasive parameter of portal hypertension that distinguishes patients with clinically significant portal hypertension. It is a strong prognostic factor for survival. | Radan Bruha Marie Jachymova Jaromir Petrtyl Karel Dvorak Martin Lenicek Petr Urbanek Tomislav Svestka Libor Vitek | 2016 | World Journal of Gastroenterology2016，22，12： | 20 |
| 19 | Management of small hepatocellular carcinoma in cirrhosis:Focus on portal hypertension显示文摘The incidence of hepatocellular carcinoma(HCC) is rising worldwide being currently the fifth most common cancer and third cause of cancer-related mortality.Early detection of HCC through surveillance programs have enabled the identification of small nodules with higher frequency,and nowadays account for 10%-15% of patients diagnosed in the West and almost 30% in Japan.Patients with small HCC can be candidates for potential curative treatments:liver transplantation,surgical resection and percutaneous ablation,depending on the presence of portal hypertension and co-morbidities.This review will analyze recent advancements in the clinical management of these individuals,focusing on issues related to the role of portal hypertension,the debate between resection and ablative therapies and the future impact of molecular technologies. | Virginia Hernandez-Gea Fanny Turon Annalisa Berzigotti Augusto Villanueva | 2013 | World Journal of Gastroenterology2013，19，8： | 20 |
| 20 | A New Method of Measurement for Elastic Wave Velocities in Minerals and Rocks at High Temperature and High Pressure and Its Significance显示文摘We developed a new method of measurement for elastic wave velocity of rocks and minerals at high temperature and high pressure in a wedge-type cubic anvil. The shear-wave and other ultrasonic wave can be identified by full wave phase analysis (FWPA), thus the velocities of compression-wave and shear-wave can be obtained in a single experiment. We have done the measurements of elastic wave velocities on pyrophyllite, etc. at high pressure (0.1—5.5 GPa) and high temperature (ambient temperature 1600℃), the ranges of the pressure and the temperature are in the head among the methods of the wave velocites measurement in laboratory in the world. | 谢鸿森 张月明 徐惠刚 侯渭 郭捷 赵鸿儒 | 1993 | Science China Chemistry1993，36，10： | 20 |
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