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| 1 | The land use and land cover change database and its relative studies in China显示文摘In the mid-1990s, we established the national operative dynamic information serving systems on natural resources and environment. During building the land-use/land-cover change (LUCC)database for the mid-1990s, 520 scenes of remotely sensed images of Landsat Thematic Mapper (TM) were interpreted into land-use/land-cover categories at scale of 1:100,000 under overall digital software environment after being geo-referenced and ortho-rectified. The vector map of land-use/land-cover in China at the scale of 1:100,000 was recently converted into a 1-km raster database that captures all ofthe high-resolution land-use information by calculating area percentage for each kind of land use category within every cell. Being designed as an operative dynamic information serving system,monitoring the change in land-use/land-cover at national level was executed. We have completed the updating of LUCC database by comparing the TM data in the mid-1990s with new data sources received during 1999-2000 and 1989-1990. The LUCC database has supported greatly the national LUCC research program in China and some relative studies are incompletely reviewed in this paper. | LIU Jiyuan, LIU Mingliang, DENG Xiangzheng, ZhuangDafang,ZHANG Zengxiang, LUO Di(1. Inst. of Geographic Sciences and Natural Resources Research, CAS, Beijing 100101, China 2. Inst. of Remote Sensing Applications, CAS, Beijing 100101, China) | 2002 | Journal of Geographical Sciences2002，12，3： | 96 |
| 2 | XML数据库及其应用研究显示文摘XML正在成为Internet上数据描述和交换的标准,它将代替HTML而成为Web上存放数据的主要格式。XML及其一系列相关的标准已广为接受和使用,为XML成为数据库奠定了基础。文章针对XML数据库研究的现状,介绍了XML数据库的基本概念和相关技术,并对其应用领域和使用方法进行了分析和研究。 | 张素智 卢正鼎 李春林 | 2002 | 计算机工程与应用2002，38，8： | 45 |
| 3 | Chromosomal level assembly and population sequencing of the Chinese tree shrew genome显示文摘Chinese tree shrews (Tupaia belangeri chinensis) have become an increasingly important experimental animal in biomedical research due to their close relationship to primates. An accurately sequenced and assembled genome is essential for understanding the genetic features and biology of this animal. In this study, we used long-read single-molecule sequencing and high-throughput chromosome conformation capture (Hi-C) technology to obtain a high-qualitychromosome-scale scaffolding of the Chinese tree shrew genome. The new reference genome (KIZ version 2: TS_2.0) resolved problems in presently available tree shrew genomes and enabled accurate identification of large and complex repeat regions, gene structures, and species-specific genomic structural variants. In addition, by sequencing the genomes of six Chinese tree shrew individuals, we produced a comprehensive map of 12.8 M single nucleotide polymorphisms and confirmed that the major histocompatibility complex (MHC) loci and immunoglobulin gene family exhibited high nucleotide diversity in the tree shrew genome. We updated the tree shrew genome database (TreeshrewDB v2.0: http://gffzzb70c77447da74c53hn669wx95ncvw6xqv.ffgz.tsg.suse.edu.cn) to include the genome annotation information and genetic variations. The new high-quality reference genome of the Chinese tree shrew and the updated TreeshrewDB will facilitate the use of this animal in many different fields of research. | Yu Fan Mao-Sen Ye Jin-Yan Zhang Ling Xu Dan-Dan Yu Tian-Le Gu Yu-Lin Yao Jia-Qi Chen Long-Bao Lv Ping Zheng Dong-Dong Wu Guo-Jie Zhang Yong-Gang Yao | 2019 | Zoological Research2019，40，6： | 15 |
| 4 | A Collinearity-Incorporating Homology Inference Strategy for Connecting Emerging Assemblies in the Triticeae Tribe as a Pilot Practice in the Plant Pangenomic Era显示文摘Plant genome sequencing has dramatically increased,and some species even have multiple high-quality reference versions.Demands for clade-specific homology inference and analysis have increased in the pangenomic era.Here we present a novel method,GeneTribe(http://gffzz6c7fcf032cb94ff5sn669wx95ncvw6xqv.ffgz.tsg.suse.edu.cn/genetribe/),for homology inference among genetically similar genomes that incorporates gene collinearity and shows bet-ter performance than traditional sequence-similarity-based methods in terms of accuracy and scalability.The Triticeae tribe is a typical allopolyploid-rich clade with complex species relationships that includes many important crops,such as wheat,barley,and rye.We built Triticeae-GeneTribe(http://gffzzaeec8df70e7c4b21hn669wx95ncvw6xqv.ffgz.tsg.suse.edu.cn/TGT/),a homology database,by integrating 12 Triticeae genomes and 3 outgroup model genomes and implemented versatile analysis and visualization functions.With macrocollinearity analysis,we were able to construct a refined model illustrating the structural rearrangements of the 4A-5A-7B chromosomes in wheat as two major translocation events.With collinearity analysis at both the macro-and microscale,we illustrated the complex evolutionary history of homologs of the wheat vernalization gene Vm2,which evolved as a combined result of genome translocation,duplication,and polyploidization and gene loss events.Our work provides a useful practice for connecting emerging genome assemblies,with awareness of the extensive polyploidy in plants,and will help researchers efficiently exploit genome sequence re-sources. | Yongming Chen Wanjun Song Xiaoming Xie Zihao Wang Panfeng Guan Huiru Peng Yuannian Jiao Zhongfu Ni Qixin Sun Weilong Guo | 2020 | Molecular Plant2020，13，12： | 14 |
| 5 | Immune Homeostasis: Effects of Chinese Herbal Formulae and Herb-Derived Compounds on Allergic Asthma in Different Experimental Models显示文摘Allergic asthma is thought to arise from an imbalance of immune regulation, which is characterized by the production of large quantities of Ig E antibodies by B cells and a decrease of the interferon-γ/interleukin-4(Th1/Th2) ratio. Certain immunomodulatory components and Chinese herbal formulae have been used in traditional herbal medicine for thousands of years. However, there are few studies performing evidence-based Chinese medicine(CM) research on the mechanisms and efficacy of these drugs in allergic asthma. This review aims to explore the roles of Chinese herbal formulae and herb-derived compounds in experimental research models of allergic asthma. We screened published modern CM research results on the experimental effects of Chinese herbal formulae and herb-derived bioactive compounds for allergic asthma and their possible underlying mechanisms in English language articles from the Pub Med and the Google Scholar databases with the keywords allergic asthma, experimental model and Chinese herbal medicine. We found 22 Chinese herb species and 31 herb-derived anti-asthmatic compounds as well as 12 Chinese herbal formulae which showed a reduction of airway hyperresponsiveness, allergen-specific immunoglobulin E, inflammatory cell infiltration and a regulation of Th1 and Th2 cytokines in vivo, in vitro and ex vivo, respectively. Chinese herbal formulae and herbderived bioactive compounds exhibit immunomodulatory, anti-inflammatory and anti-asthma activities in different experimental models and their various mechanisms of action are being investigated in modern CM research with genomics, proteomics and metabolomics technologies, which will lead to a new era in the development of new drug discovery for allergic asthma in CM. | LIU Lu WANG Lin-peng HE Shan MA Yan | 2018 | Chinese Journal of Integrative Medicine2018，24，5： | 14 |
| 6 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 7 | 美国ISI公司网络版引文索引数据库评价显示文摘The general situation of Web of Science,a new product of Institute for Scientific Information,USA,is introduced,including its coverage,characteristics and new collections.Its functions are also assessed. | 华薇娜 施云 岳泉 | 2001 | 情报理论与实践2001，24，1： | 11 |
| 8 | 一种利用小波变换逼近信号滤除心电图基线漂移的方法显示文摘该文提出了一种利用小波变换逼近信号滤除心电图(ECG)基线漂移的方法。该方法的基本思想是:通过对ECG信号进行多尺度分解,利用分解后所得的逼近信号充分逼近ECG中的基线漂移噪声的特性,从而滤除ECG中的基线漂移分量。将该方法应用于MIT-BIHDatabase眼1演提供的30分钟的真实ECG记录上,结果显示该方法能较好地滤除ECG基线漂移,且对信号的其他成分损害较小。 | 张文琼 刘肖琳 吴涛 | 2005 | 计算机工程与应用2005，41，20： | 11 |
| 9 | Features of colorectal cancer in China stratified by anatomic sites:A hospital-based study conducted in university-affiliated hospitals from 2014 to 2018显示文摘Objective:The clinical and biological characteristics of colorectal cancer have been found to differ depending on the anatomic site of the cancer.However,for Chinese patients,there is limited information on the proportion of cases at each site and the related features.In this study,we explored the location,distribution and other features of colorectal cancers at each anatomic site in Chinese patients.Methods:We conducted a hospital-based study using hospitalization summary reports from 10 Peking University-affiliated hospitals from 2014 to 2018;the reports covered a total of 2,097,347 hospitalizations.Incident cases were chosen as the study population,and their epidemiological features were further analyzed.Results:A total of 20,739 colorectal cancer patients were identified.Rectum was the most common location(48.3%)of the cancer,whereas the proportions of patients with distal and proximal colon cancer were 24.5%and18.6%,respectively.Patients with rectal cancer were predominantly male and were the youngest for all anatomical sites(each P<0.001).The highest proportion of emergency admissions,the longest hospital stays and the highest hospitalization costs were found in patients with proximal colon cancer(each P<0.001).The proximal colon cancer subgroup included the highest proportions of patients with medical histories of cholecystectomy,cholecystolithiasis and/or gallbladder polyps and appendectomy(P=0.009,P<0.001 and P<0.001,respectively).The distal colon cancer subgroup included the highest proportions of patients with medical histories of diabetes and hypertension(P<0.001,respectively).Conclusions:The patterns of colorectal cancer observed in this study differ from those reported for Western patients and show a significantly higher proportion of patients with rectal cancer.Different epidemiological features were also found based on anatomic sites.Further studies based on tumor location should be conducted to facilitate more accurate screening and treatment. | Ruize Qu Yanpeng Ma Liyuan Tao Xiaoyuan Bao Xin Zhou Bingyan Wang Fei Li Siyi Lu Lin Tuo Siyan Zhan Zhipeng Zhang Wei Fu | 2021 | Chinese Journal of Cancer Research2021，33，4： | 10 |
| 10 | 基于SDE的全关系空间数据库的实现显示文摘在介绍空间数据库和ESRI空间数据库引擎SDE(SpatialDatabaseEngine)的基础上,分析了把空间数据和属性数据集中存放于RDBMS的数据组织方式,论述了在企业级分布式应用系统中,空间数据的空间分析方法,以及空间数据的索引和查询方法。 | 甘泉 卢正 李永树 | 2003 | 四川测绘2003，26，2： | 9 |
| 11 | 基于ASP的数据库连接显示文摘文章讨论了三种基于ADO的数据库访问及其实现技术;并采用服务器端中间层组件技术,使得数据访问和商业规则从客户端转移到了服务端,从而保证了商务应用中数据库访问的安全性。 | 唐汇国 张泰山 陈志盛 | 2003 | 计算机工程与应用2003，39，31： | 9 |
| 12 | Java语言与DataBase之间的接口─—JDBC显示文摘本文全面分析了作为Java语言与DataBase之间接口的JDBC,包括它的工作原理,构成接口的组成部分,以及各部分之间的工作关系。并介绍了作为JDBC工作基础的Driver的原理和分类。例举了JDBC与ODBC之间的几.点差异,描述了应用JDBC之后,给网络环境下的信息系统所带来的变化。 | 罗东川 | 1998 | 计算机系统应用1998，7，3： | 8 |
| 13 | Research and development of Chinese LCA database and LCA software显示文摘This paper detailed introduces the related work for building Chinese National Database, Sinocenter, of materials life cycle assessment (MLCA) and developing the environmental burden dataset of materials. The MLCA database was built in 2004, and the basic framework mainly includes LCA methodology, materials environmental dataset about energy consumption, resource input and environmental emissions. Nowadays, the database contains about fifty-thousand records of the main materials industries, such as cement, iron and steel, nonferrous metal, etc., and also includes the primary LCI data of fossil fuels and electricity grid in China. At the same time, the LCA method localization work is going on, for instance, calculated the resource characterization factors of 42 kinds of metal and 58 sorts of nonmetal, and also obtained some heavy metal impact factors in water. Based on the database, the iron and steel dataset has been developed with the data quality analysis, and some environmental burden data could be queried in our website, www.cnmlca.com, in the future. Lastly, according to the framework of the ISO14040 series standards, the antitype of Chinese LCA evaluation system was developed to support materials and products LCA evaluation in China. | GONG Xianzheng NIE Zuoren Wang Zhihong ZUO Tieyong | 2006 | Rare Metals2006，25，z2： | 8 |
| 14 | 传感器数据库管理系统设计显示文摘以VC++为界面开发工具,利用ACCESS作为后台数据库,开发了传感器数据库管理系统。在数据库设计过程中,进行了数据库系统功能分析、数据库表设计、ADO类封装以及界面框架设计,其功能在实际应用中使用情况良好,为数量庞大的传感器的日常管理和检定提供了方便的途径。 | 何志勇 赵瑞国 袁军社 | 2010 | 火箭推进2010，36，6： | 8 |
| 15 | 社会工作质性评估研究的回顾(1990-2003)对中国社会工作的启示显示文摘Objective: This paper reviewed and examined the quality of all the qualitative evaluation studies indexed by two key search terms of “qualitative” and “evaluation” in the Social Work Abstracts database from 1990 to 2003 against a number of criteria typically adopted in the field of qualitative research. The review led to a dissatisfactory finding of the low quality of many qualitative evaluation studies due to their insensitivity to the following issues: philosophical basis of the study, auditability (detailed documentation of the participants and data collecting procedure), biases (acknowledgement of biases and preoccupation, and steps to deal with them), credibility or trustworthiness (triangulation, peer checking and participant verification of the findings), consistency (reliability consciousness and audit trails), and critical interpretation of the data (alternative explanations, disconfirming evidence, and limitations of the study). It was recommended that researchers be cautious when utilizing findings from the published qualitative evaluation studies; that social workers be sensitive to the issue of quality when conducting qualitative evaluation studies; that researchers be critical when judging the qualitative evaluation studies in social work; that researchers develop a clear set of guidelines for qualitative studies; that social work training institutes design qualified qualitative research courses; that a database of social work in China be established; that researchers be engaged in more qualitative studies that demonstrate high quality; that myths in qualitative research be debunked; and that adequate training for social workers on qualitative evaluation studies be provided. | 石丹理 韩晓燕 邓敏如 | 2005 | 社会2005，25，3： | 8 |
| 16 | 基于OSPF链路状态数据库构建网络拓扑显示文摘构建局域网拓扑在网络行为的研究中具有非常重要的意义。文中以利用OSPF协议构建局域网拓扑结构为目标,对目前几种构建局域网拓扑结构的方法进行比较,通过分析比较指出利用OSPF协议构建局域网拓扑结构的优点,然后提出了一种基于OSPF协议链路状态数据库进行局域网拓扑构造算法。该算法在对OSPF链路状态数据库中的OSP Fdatabase表和OSPF database network表详细分析的基础上,利用这两个表中的数据构建网络拓扑。实验证明,该算法能够有效地显示局域网拓扑结构。 | 倪勇 史怀洲 朱培栋 | 2009 | 计算机技术与发展2009，19，3： | 8 |
| 17 | 基于SDE与MapObjects控件的GIS开发应用研究显示文摘阐述基于ActiveX组件技术的控件MapObjects的运行机制,主要包括:MapObjiects的功能,利用MapObjects开发GIS系统的基本步骤;空间数据引擎(SpatialDatabaseEngine)在当前的地理信息系统(GeographiclnformationSystem)应用中的功能。 | 张宁 宫辉力 赵文吉 赵宝奎 杨洪荣 | 2005 | 首都师范大学学报(自然科学版)2005，26，2： | 7 |
| 18 | Oracle standby database的建立与维护显示文摘Standbydatabase是oracle数据库的一种有效容错方式,可用来进行数据灾难恢复。详细介绍了Standbydatabase的建立过程和如何对Standbydatabase进行维护,并给出了常见问题的解决方法。 | 张岩 | 2005 | 医疗卫生装备2005，26，8： | 6 |
| 19 | 基于GIS的甘肃省黄河流域水资源管理信息系统的设计与实现显示文摘针对甘肃省黄河流域水资源利用现状,面向水资源可持续管理,利用Geodatabase技术组织水资源相关的空间和属性数据,在ArcGIS Engine平台上进行二次开发,构建了甘肃省黄河流域水资源管理信息系统。该系统充分发挥了地理信息系统所具有的空间数据显示、管理、分析的优势,并以水资源管理部门的日常工作为基础,实现了水资源空间数据的可视化管理、查询统计、空间分析、专题制图以及对取水许可、取水计量等水资源工作流的综合管理等功能。 | 周伟 马金辉 李成六 邢钊 | 2011 | 节水灌溉2011，，11： | 6 |
| 20 | 基于ObjectARX的ASI编程技术及应用显示文摘本文以AutoCADR14为开发平台,讨论了基于ObjectARX的数据库接口(ASI)程序设计方法及在标准件库和BOM中的应用。 | 闵落明 王霄 蔡兰 | 1999 | 计算机辅助设计与制造1999，，4： | 6 |
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