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| 1 | The relation between HLA-DQA1 genes and genetic susceptibility to duodenal ulcer in Wuhan Hans显示文摘AIM To study the genetic susceptibility of HLA-DQA1 alleles to duodenal ulcer in Wuhan Hans.METHODS Seventy patients with duodenalulcer and fifty healthy controls were examinedfor HLA-DQA1 genotypes.HLA-DQA1 typing wascarried out by digesting the locus specificpolymerase chain reaction amplified productswith alleles specific restriction enzymes(PCR-RFLP),i.e.,Apal Ⅰ,Bsaj Ⅰ,Hph Ⅰ,Fok Ⅰ,Mbo Ⅱ and Mnl Ⅰ.RESULTS The allele frequencies of DQA1 * 0301and DQA1 * 0102 in patients with duodenal ulcerwere significantly higher and lower respectivelythan those in healthy controls(0.40 vs 0.20,P = 0.003,mcorret = 0.024)and(0.05 vs 0.14,P = 0.012,but Pcorret>0.05),respectively.CONCLUSION DQA1 * 0301 is a susceptiblegene for duodenal ulcer in Wuhan Hans,andthere are immunogenetic differences in HLA-DQA1 locus between duodenal ulcer patients andhealthy controls. | Du YP Deng CS Lu DY Huang MF Guo SF Hou W | 2000 | World Journal of Gastroenterology2000，6，1： | 37 |
| 2 | Application of isolation forest to extract multivariate anomalies from geochemical exploration data显示文摘Constructing a statistical model that best fits the background is a key step in geochemical anomaly identification. But the model is hard to be constructed in situations where the sample population has unknown and/or complex distribution. Isolation forest is an outlier detection approach that explicitly isolates anomaly samples rather than models the population distribution. It can extract multivariate anomalies from huge-sized high-dimensional data with unknown population distribution. For this reason,we tentatively applied the method to identify multivariate anomalies from the stream sediment survey data of the Lalingzaohuo district,an area with a complex geological setting,in Qinghai Province in China. The performance of the isolation forest algorithm in anomaly identification was compared with that of a continuous restricted Boltzmann machine. The results show that the isolation forest model performs superiorly to the continuous restricted Boltzmann machine in multivariate anomaly identification in terms of receiver operating characteristic curve,area under the curve,and data-processing efficiency. The anomalies identified by the isolation forest model occupy 19% of the study area and contain 82% of the known mineral deposits,whereas the anomalies identified by the continuous restricted Boltzmann machine occupy 35% of the study area and contain 88% of the known mineral deposits. It takes 4. 07 and 279. 36 seconds respectively handling the dataset using the two models. Therefore,isolation forest is a useful anomaly detection method that can quickly extract multivariate anomalies from geochemical exploration data. | WU Wei CHEN Yongliang | 2018 | Global Geology2018，21，1： | 9 |
| 3 | Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors显示文摘Achievement of immunocompetent and therapeutic T lymphopoiesis from pluripotent stem cells(PSCs)is a central aim in T cell regenerative medicine.To date,preferentially reconstituting T lymphopoiesis in vivo from PSCs remains a practical challenge.Here we documented that synergistic and transient expression of Runx1 and Hoxa9 restricted in the time window of endothelial-to-hematopoietic transition and hematopoietic maturation stages in a PSC differentiation scheme(iR9-PSC)in vitro induced preferential generation of engraftable hematopoietic progenitors capable of homing to thymus and developing into mature T cells in primary and secondary immunodeficient recipients.Single-cell transcriptome and functional analyses illustrated the cellular trajectory of T lineage induction from PSCs,unveiling the T-lineage specification determined at as early as hemogenic endothelial cell stage and identifying the bona fide pre-thymic progenitors.The induced T cells distributed normally in central and peripheral lymphoid organs and exhibited abundant TCRαβrepertoire.The regenerative T lymphopoiesis restored immune surveillance in immunodeficient mice.Furthermore,gene-edited iR9-PSCs produced tumor-specific T cells in vivo that effectively eradicated tumor cells.This study provides insight into universal generation of functional and therapeutic T cells from the unlimited and editable PSC source. | Rongqun Guo Fangxiao Hu Qitong Weng Cui Lv Hongling Wu Lijuan Liu Zongcheng Li Yang Zeng Zhijie Bai Mengyun Zhang Yuting Liu Xiaofei Liu Chengxiang Xia Tongjie Wang Peiqing Zhou Kaitao Wang Yong Dong Yuxuan Luo Xiangzhong Zhang Yuxian Guan Yang Geng Juan Du Yangqiu Li Yu Lan Jiekai Chen Bing Liu Jinyong Wang | 2020 | Cell Research2020，30，1： | 7 |
| 4 | Planetary Stationary Waves in the Atmosphere Part I: Orographic Stationary Waves显示文摘It is proposed that the orographic stationary waves are required by long-term balance of momentum in the atmosphere with zonally asymmetric orographic forcing. This hypothesis may be confirmed successfully with the theoretical model of geostrophic waves. In the Part I, we will explain the observed phase distributions of orographic stationary waves at middle and high latitudes of the Northern Hemisphere, according to the long-term balance of zonal momentum over the stationary orographic forcing. It is revealed that the geographic distribution of stationary waves depends not only on local topgraphy but also on mean circulation fields and angular momentum flux in the atmosphere. So these waves cannot be simulated by the models in a restricted area. | Yong. L. McHall | 1991 | Advances in Atmospheric Sciences1991，8，2： | 7 |
| 5 | DISTRIBUTION AND ABUNDANCE OF EGGS AND LARVAE OF ANTARCTIC KRILL(ENPHAUSUA SUPERBADANA)IN ANTARCTIC PENINSULA AREA显示文摘During the First Chinese Antarctic Expedition zooplankton samples were collected at each of the oceanography stations in the waters around South Sheltland Islands (S. S. Is.) and in the northern part of the Bellinshausen Sea from 20 January to 12 February, 1985 by vertical tows of an 80 cm diameter conical net from 200 m to surface. Two deep tows with a closing net. were performed in slope water north of S.S. Is, and in the basin of Bransfield Strait. Eggs and larvae of Euphatisia superba Dana in zooplankton samples were identified and counted.There were four records of eggs from 27 stations. Most catches were of small number and restricted to within the nearshore area south of S.S Is.The largest number (1500/1000 cubic meters )was found in the outer side of Smith Island.No Nauplius was found . The earliest stage we found <was Metanauplius , in two deep tows. The distribution of Calyptopis MI and Furcili I-III were quite similar. They were found mainly in three areas: 1 ) nearshore water along the | 王荣 | 1989 | Chinese Journal of Oceanology and Limnology1989，7，2： | 7 |
| 6 | Interleukin 10 prevents dendritic ceil accumulation and vaccination with granulocyte macrophage colony-stimulating factor gene modified tumor cells显示文摘A wide variety of human tumors express interleukin10 (IL-10) for reasons poorly understood. We haveanalysed the effect of spontaneous IL-10 expression by amouse tumor (J558L) on its immunparalysing effect.Because cross-priming' of T cells by host antigenpresenting cells for MHC class I restricted tumor antigensis a major pathway for induction of tumor immunity andthat is enhanced by granulocyte-macrophage colony-stimulating factor (GM-CSF), we expressed this cytokinein J558L cells. GM-CSF secreting cells were not | Gabriele Noffz Mariette Mohaupt Thomas Blankenstein | 1997 | 中国实验血液学杂志1997，5，3： | 7 |
| 7 | The First National Prevalence of Autism Spectrum Disorder in China显示文摘Autism spectrum disorder (ASD) is a complex developmental disability characterized by impaired social interaction and communication,restricted interests,and stereotypical behaviors [1,2].In addition to these core diagnostic features,children with ASD frequently present with a host of associated behavioral issues,such as intellectual disability and epilepsy,as well as feeding and sleep problems.The prevalence of ASD in the United States is about 1/59,with a significantly higher proportion in males [3].Therefore,ASD is no longer a rare disorder. | Zi Chao Zhang Junhai Han | 2020 | Neuroscience Bulletin2020，36，9： | 5 |
| 8 | Orbit design for the Laser Interferometer Space Antenna (LISA)显示文摘The Laser Interferometer Space Antenna (LISA) is a joint ESA-NASA mission for detecting low-frequency gravitational waves in the frequency range from 0.1 mHz to 1 Hz, by using accurate laser interferometry between three spacecrafts, which will be launched around 2018 and one year later reach their operational orbits around the Sun. In order to operate successfully, it is crucial for the constellation of the three spacecrafts to have extremely high stability. Based on the study of operational orbits for a 2015 launch, we design the operational orbits of beginning epoch on 2019-03-01, and introduce the method of orbit design and optimization. We design the orbits of the transfer from Earth to the operational orbits, including launch phase and separation phase; furthermore, the relationship between energy requirement and flight time of these two orbit phases is investigated. Finally, an example of the whole orbit design is presented. | Gerhard HEINZEL Albrecht RDIGER | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，1： | 4 |
| 9 | Fiducial intervals of restricted parameters and their applications显示文摘In practice, the unknown parameters are often restricted. This paper provides a general method for constructing the fiducial intervals of the restricted parameters. Applying the general method, the fiducial intervals are constructed for the location (scale)parameters and the difference (ratio) of two locations (scales) in a location (scale) family of distributions. The frequency properties of these intervals are verified. For a variance components model, the fiducial intervals for the three parameters of common interest are obtained. Their frequency properties are investigated theoretically and computationally. | LI Xinmin, LI Guoying & XU Xingzhong College of Mathematics and Information Sciences, Shandong University of Technology, Zibo 255049, China Academy of Mathematics and System Sciences, Chinese Academy of Sciences, Beijing 100800, China Department of Mathematics, Beijing Institute of Technology, Beijing 100801, China | 2005 | Science China Mathematics2005，48，11： | 4 |
| 10 | Embedding theorem of Z-graded Lie superalgebras显示文摘The embedding theorem of Z-gra ded Lie superalgebras is given and proved. As a subsidiary result it is proved that a transitive Z-graded restricted Lie superalgebra G= i≥- 1G i must be isomorphic to W(m,n,1) if the dim ension of G 1 satisfies a certain condition. | 张永正 沈光宇 | 1998 | Science China Mathematics1998，41，10： | 4 |
| 11 | The Research on Countermeasures of Green Agricultural Development in Jiangsu Province显示文摘Firstly,the thesis introduces the connotation of green agriculture,indicating that the green agriculture has 4 characteristics,namely openness,continuity,high efficiency and standardization,compared with the traditional agricultural development model.Secondly,the advantages of developing green agriculture in Jiangsu Province are discussed,namely rich agricultural resources,notable technological advantage,solid agricultural foundation,high quality of agricultural products,great market prospect of green consumption,and notable policy advantage.In view of the increasing shortage of natural resources,increasing restriction of rural labor force,increasing deterioration of rural environment,inadequate popularization of green agriculture,and fierce competition at home and abroad,the restricted factors of developing green agriculture in Jiangsu Province are introduced.Finally,in view of the agricultural concept innovation,green agricultural system innovation,agricultural technology innovation,agricultural management innovation,operation system innovation,ecological system innovation,development of tourism agriculture and regional differentiation development strategy,the relevant countermeasures and suggestions are put forward,in order to explore a new agricultural development model for Jiangsu's modern agricultural development. | DU Hua-zhang Jiangyan Municipal Bureau of Agriculture,Jiangyan 225500,China | 2010 | Asian Agricultural Research2010，2，3： | 3 |
| 12 | Compressed Sensing of IR-UWB Wireless Sensor Network Data Based on Two-Dimensional Measurements显示文摘A novel Compressed sensing(CS) method based on two-dimensional measurements is proposed that can be effectively utilized in Impulse radio ultra-wideband wireless sensor networks(IR-UWB WSNs) to significantly reduce the energy consumption and sampling rate in sensor data transferring. We start by establishing the CS measurement model by taking both spatial and temporal correlations of Wireless sensor network(WSN) data into account. Since our model incorporates a new type of measurement matrix: the block quasi-Toeplitz structured matrix, we derive the Restricted isometry property(RIP)of the block quasi-Toeplitz structured matrix to ensure the performance of the two-dimensional recovery of WSNs data. We substantiate our mathematical analysis by numerical examples in the context of ideal spares vector and real WSN data, and results demonstrate that the approach achieves significantly saving of energy and sampling rate with small reconstruction error. | WANG Kai LIU Yulin WAN Qun JING Xiaojun | 2015 | Chinese Journal of Electronics2015，24，3： | 3 |
| 13 | Ethnobotanical inventory and medicinal uses of some important woody plant species of Kotli,Azad Kashmir,Pakistan显示文摘Objective:To document ethnobotanical informations of useful woody plant species in the region of Kotli,Azad Kashmir.Methods:An ethnobotanical survey was conducted in Kotli.Data were collected by interview and semi structured questionnaire from selected local informants and traditional practitioners as well as by field assessment.Results:The present study documented the etnobotanical uses of 33 woody plant species.Most of the species have been used for dual purpose.Only 5 species are used for one purpose.Study revealed all species have medicinal value,among which 21 were used as fuel wood species,16 as fodder species,4 as timber wood species,12 as edible fruit species,6 as fence or hedge plant,7 as ornamental species and 12 species had other uses.Conclusions:Medicinal plants are still widely used for health care by locals of Kotli.Some species of woodlands seem to be vulnerable to overcollection and deforestation.As the young generation is diverted toward allelopathic medicines,ethnobotanical knowledges of important medicinal plants are restricted to the old people only.It is suggested to close the forest of district Kotli for next two to three decades for the conservation of plant biodiversity. | Muhammad Shoaib Amjad Muhammad Arshad | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，12： | 3 |
| 14 | Geometric Characterizations for Variational Minimization Solutions of the 3-Body Problem | Yiming Long Nankai Institute of Mathematics. Nankai University. Tianjin 300071. P. R. China Shiqing Zhang Department of Applied Mathematics Chongqing University. Chongqing 40004, P.R. China | 2000 | Acta Mathematica Sinica,English Series2000，16，4： | 3 |
| 15 | 光气的太赫兹/红外吸收及拉曼散射振动光谱研究显示文摘采用Restricted Hartree-Fock(RHF)自洽场方法和密度泛函理论(DFT)方法对光气(COCl2)进行了RHF/6-31G、RHF/6-31+G、RHF/6-31++G、RHF/6-311G、RB3LYP/6-31G、RB3LYP/6-311G、RB3LYP/6-31+G、RB3LYP/6-31++G、RB3LYP/6-31G(d)、UB3LYP/6-31G十种水平上的分子结构优化、分子振动模、振动频率及强度的理论计算。研究结果表明:理论计算结果与实验数据吻合得很好,用DFT计算方法的RB3LYP/6-31G(d)基组能获得与实验结果最为接近的理论计算数据,其计算的红外频率与红外实验测试频率的相对偏差绝对值的平均值为2.43%。COCl2各种太赫兹、红外振动模的理论计算活性由大至小的顺序分别为:CCl2 a-str>CO str>CCl2 s-str>Op-deform>CO deform>CCl2 deform。COCl2各种拉曼振动模的理论计算活性由大至小的顺序分别为:CCl2 s-str>CO str>CO deform>CCl2 deform>CCl2 a-str>Op-deform。由于COCl2在9 THz有明显的THz特征吸收和拉曼散射振动,基于这一特性有望开发出毒气的太赫兹快速检测技术。 | 唐利斌 姬荣斌 刘树平 王忆锋 叶婧 台国安 魏长松 陆志文 许扬羽 宋立媛 陈雪梅 马钰 | 2011 | 红外技术2011，33，2： | 3 |
| 16 | Perioperative restricted fluid therapy preserves immunological function in patients with colorectal cancer显示文摘AIM:To investigate the effect of perioperative restricted fluid therapy on circulating CD4+/CD8+T lymphocyte ratio,percentage of regulatory T cells(Treg)and postoperative complications in patients with colorectal cancer.METHODS:A total of 185 patients met the inclusion criteria and were included in the randomized clinical trial.These patients were divided into two groups according to receipt of either perioperative standard(S,n=89)or restricted(R,n=96)fluid therapy.Clinical data of these patients were collected in this prospective study.Perioperative complications and cellular immunity changes(CD4+/CD8+and Treg)were analyzed comparatively between the two groups.RESULTS:Both during surgery and on postoperativedays,the total volumes of fluids administered in the R group were significantly lower than those in the S group(1620±430 mL vs 3110±840 mL;2090±360mL vs 2750±570 mL;1750±260 mL vs 2740±490mL;1620±310 mL vs 2520±300 mL;P<0.05).Decreased ratios of circulating CD4+/CD8+T lymphocytes(1.47±0.28 vs 2.13±0.26;1.39±0.32 vs 2.21±0.24;P<0.05)and Treg percentage values(2.79±1.24vs 4.26±1.04;2.46±0.98 vs 4.30±1.12;P<0.05)were observed after surgery in both groups.However,in the R group,these values restored more quickly starting from postoperative day 2(1.44±0.24 vs 1.34±0.27;2.93±1.08 vs 2.52±0.96;P<0.05).The proportion of patients with complications was significantly lower in the restricted group(36 of 89 vs 59 of 96,P<0.01).CONCLUSION:Perioperative restricted intravenous fluid regimen leads to a low postoperative complication rate and better cellular immunity preservation in patients with colorectal cancer. | Hong-Ying Jie Ji-Lu Ye Hai-Hua Zhou Yun-Xiang Li | 2014 | World Journal of Gastroenterology2014，20，42： | 3 |
| 17 | A new definition of restricted Lie superalgebras显示文摘A new definition of restricted Lie superalgebras has been given; some important results on the representation theory of restricted Lie superalgebra have been obtained. | WANG Ying & ZHANG Yongzheng1. Department of Mathematics, Harbin Institute Technology, Harbin 150001, China 2. Department of Mathematics, Northeast Normal University, Changchun 130024, China | 2000 | Chinese Science Bulletin2000，45，4： | 3 |
| 18 | Remarkable Species Diversity on Adjacent Salt Lakes in South Australia显示文摘Lakes Acraman,Gairdner,Harris and Everard are a cluster of large episodic salt lakes on Eyre Peninsula,South Australia.These lakes have a characteristic terrestrial invertebrate fauna including various spiders, | Peter HUDSON | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 2 |
| 19 | Photogravitationally Restricted Three-Body Problem and Coplanar Libration Point显示文摘The photogravitationally restricted three-body problem in which the mass reduction factors of two primaries q_(1),q_(2)∈(-∞,1]is studied and the calculating formula of the location of coplanar libration points is given in this paper.As an application,the motion of cometary dust in the solar system and dust grain in binary AR Cas is also discussed. | ZHENG Xuetang YU Lizhong | 1993 | Chinese Physics Letters1993，10，1： | 2 |
| 20 | PROPER SPLITTINGS FOR RESTRICTED LINEAR EQUATIONS AND THE GENERALIZED INVERSE A_(T,S)~2显示文摘This paper presents a proper splitting iterative method for comparing the general restricted linear euqations Ax=b, x ∈T (where, b ∈AT, and T is an arbitrary but fixed subspace of Cm) and the generalized in AT,S For the special case when b ∈AT and dim(T)=dim(AT), this splitting iterative methverse AT,S hod converges to AT,Sb (the unique solution of the general restricted system Ax=bx ∈T). | 王国荣 魏益民 | 1998 | Numerical Mathematics A Journal of Chinese Universities(English Series)1998，7，1： | 2 |
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