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| 1 | CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells显示文摘 | Xiaojuan Liu Yongping Zhang Chen Cheng Albert W Cheng Xingying Zhang Na Li Changqing Xia Xiaofei Wei Xiang Liu Haoyi Wang | 2017 | Cell Research2017，27，1： | 40 |
| 2 | Adventitious root formation in rice requires OsGNOM1 and is mediated by the OsPINs family显示文摘在谷物的含纤维的根系统包括首先偶然根(艺术) ,它在营养素和水举起起重要作用。关于位于 AR 开发下面的分子的机制的当前的知识仍然是有限的。我们这里报导四米饭(Oryza sativa L.) 的隔离异种从不同基因背景,所有哪个在 AR 是有缺点的形成。这些异种展出了侧面的根(LR ) 和 gravitropism 的部分损失的减少的数字。也显示的异种提高了敏感到 N-1-naphthylphthalamic 酸,极的植物生长素运输的一个禁止者(轻拍) ,显示变化影响了植物生长素运输。用四异种之一的位置的克隆表明它被一个 guanine 核苷酸交换因素的 loss-of-function 为 ADP-ribosylation 因素(OsGNOM1 ) 引起。转基因的植物显示出的 promoter::GUS 的 RT-PCR 和分析那 OsGNOM1 在 AR primordia,脉管的纸巾, LR,根尖端,叶子,花药和词根静脉被表示,与类似于植物生长素的一个分发模式。另外, OsPIN2, OsPIN5b 和 OsPIN9 的表情在异种被改变。一起拿,这些调查结果显示 OsGNOM1 通过调整影响艺术的形成轻拍。 | Shiping Liu Jirong Wang Lu Wang Xiaofei Wang Yanhong Xue Ping Wu Huixia Shou | 2009 | Cell Research2009，19，9： | 29 |
| 3 | Granitic magmatism related to early Paleozoic continental collision in North Qinling显示文摘Zircon U-Pb dating of early Paleozoic granitoids in North Qinling yields three age peaks of^500,~452 and^420 Ma.They can be temporally correlated with high-pressure to ultrahigh-pressure metamorphism at ca.500 Ma,retrograde granulite-facies metamorphisms at ca.450 Ma and amphibolite-facies metamorphism at ca.420 Ma,respectively.The first episode of granitic magmatism is considered to have resulted from continental collision,whereas the second and third episodes of magmatism are attributed to crustal uplifting.Combined with the regional geological setting and new results from high-pressure and ultrahigh-pressure metamorphic rocks,the ca.500 Ma magmatism is interpreted as the result of partial melting of sedimentary rocks in accretionary wedge between the south Qinling microcontinent and the north Qinling belt including the southern margin of the North China Craton.The ca.450 Ma intensive magmatism is ascribed to dehydration melting of deeply subducted continental crust at thickened conditions in response to slab breakoff,and the final magmatism in ca.420 Ma is interpreted as the product of partial melting during the tectonic transition from contraction to extension. | ZHANG ChengLi LIU Liang WANG Tao WANG XiaoXia LI Lei GONG QiFu LI XiaoFei | 2013 | Chinese Science Bulletin2013，58，35： | 30 |
| 4 | Proteomics Associated with Virulence Differentiation of Curvularia lunata in Maize in China显示文摘蛋白质的一个维的电气泳动(1-DE ) ,蛋白质的 two-dimensionalelectrophoresis (2-DE ) 并且 cDNA 顺序克隆被用来学习 Curvularia lunata 的毒力区别[Cochliobolus lunatus ] 在中国从玉米(Zea maydis ) 孤立。从蛋白质的 1-DE 胶化侧面, 110 个可再现的乐队与六被分开 C 孤立。lunata CX-3, SD-6, C-152, C107-1, DD-60 和 W-18。68 个乐队(61.82%) 是多态的,建议在 isolates 之中的巨大的生物多样性。所有孤立组由 0.605 的系数价值由不同剧毒的类型组成因为实验被聚类进三。组织 1,由有高毒力的 CX-3, SD-6 和 C-152 组成比组显示了更多的蛋白质乐队第 2a 3,与低毒力由 C107-1 和 DD-60 组成。Proteomics 途径基于 2-DEtechniques 被使用识别在 CX-3 和 DD-60 与毒力区别联系的特定的蛋白质。423 个蛋白质点的一个总数被分开。从他们, 75 个特定的蛋白质点在 2-DE 胶化被显示。在他们之中, 28 个蛋白质点在 CX-3 是唯一的, 8 在两 2-DE 胶化上在 DD-60,和 39 个蛋白质点被显示出,但是在紧张不同地表示。包括三个唯一的蛋白质点和 17 差别的 Twentyprotein 点在 CX-3 表示了蛋白质点(超过 2 褶层 DD-60 ) 进一步与 MALDI-TOF MS/MS 被识别。结果显示大多数识别蛋白质被发现与毒力区别,新陈代谢,压力反应和信号转导被联系。他们之一作为 Brn1 蛋白质被识别,它被报导了在真菌与黑素生合成和毒力区别有关。与我们的以前的调查结果结合了,我们假设那 Brn1 蛋白质和它的调整产品可能涉及 C 的毒力区别。lunata。因而,我们克隆 Brn1cDNA 碎片并且在另外的真菌与碎片联盟。结果显示 Brn1 的 633-bpsequence 在 C 克隆。lunata 是高度与比较真菌逻辑的人。为在我们的情况中的 Brn1 的准确基因角色的进一步的工作是在进行之中的…… | Shufa Xu Jie Chen Lixing Liu Xiaofei Wang Xiuli Huang Yuhong Zhai | 2007 | Journal of Integrative Plant Biology2007，49，4： | 25 |
| 5 | Federated Learning for 6G Communications:Challenges,Methods,and Future Directions显示文摘As the 5G communication networks are being widely deployed worldwide,both industry and academia have started to move beyond 5G and explore 6G communications.It is generally believed that 6G will be established on ubiquitous Artificial Intelligence(AI)to achieve data-driven Machine Learning(ML)solutions in heterogeneous and massive-scale networks.However,traditional ML techniques require centralized data collection and processing by a central server,which is becoming a bottleneck of large-scale implementation in daily life due to significantly increasing privacy concerns.Federated learning,as an emerging distributed AI approach with privacy preservation nature,is particularly attractive for various wireless applications,especially being treated as one of the vital solutions to achieve ubiquitous AI in 6G.In this article,we first introduce the integration of 6G and federated learning and provide potential federated learning applications for 6G.We then describe key technical challenges,the corresponding federated learning methods,and open problems for future research on federated learning in the context of 6G communications. | Yi Liu Xingliang Yuan Zehui Xiong Jiawen Kang Xiaofei Wang Dusit Niyato | 2020 | China Communications2020，17，9： | 21 |
| 6 | Spatial pattern and decadal change of agro-meteorological disasters in the main wheat production area of China during 1991-2009显示文摘Agro-meteorological disasters(AMD) have become more frequent with climate warming. In this study, the temporal and spatial changes in the occurrence frequency of major meteorological disasters on wheat production were firstly explored by analyzing the observed records at national agro-meteorological stations(AMS) of China from 1991 to 2009. Furthermore, impact of climate change on AMD was discussed by comparing the warmer decade(2000–2009) with another decade(1991–2000). It was found that drought was the most frequent disaster during the last two decades, with a highest proportion of 79%. And the frequency of AMD increased significantly with climate change. Specifically, the main disasters occurred more frequently in the reproductive period than in the vegetative period. Besides, the spatial changes in the AMD frequency were characterized by region-specific. For example, the wheat cultivation areas located on the Loess Plateau and the middle-lower reaches of the Yellow River suffered mainly from drought. All these results were strongly linked to climate change in China. Therefore, sound adaptation options should be taken based on the latest changes of AMD under global warming to reduce agricultural damages. | ZHANG Zhao WANG Pin CHEN Yi ZHANG Shuai TAO Fulu LIU Xiaofei | 2014 | Journal of Geographical Sciences2014，24，3： | 19 |
| 7 | Tissue clearing of both hard and soft tissue organs with the PEGASOS method显示文摘织物空地技术由转织物在 3 尺寸(3-D ) 启用不透明的机关和纸巾的可视化透明。当前的组织空地方法被能与每个单个协议被清除的纸巾的有限类型限制,它不可避免地导致了存在在整个身体或身体部分成像以内盲点。包括骨头和牙齿的难纸巾仍然是要清除的最困难的机关。另外,内长的荧光的损失为基于溶剂的空地方法仍然是一颗主要担心。这里,我们发展了聚乙烯乙二醇(木钉) 联系了溶剂系统(PEGASOS ) ,它将近显示了纸巾的所有类型透明、保存的内长的荧光。骨头和牙齿能被转在变清以后将近不可见。PEGASOS 方法转了透明的整个成年老鼠身体,我们对一个成年老鼠头骨头,牙齿,大脑,肌肉,和其它填写了的图象有能力没有盲目区域的纸巾。难织物透明性使我们能重建在 3-D 的未经触动的上颚,牙齿,腿节,或膝关节。另外,我们在长距离上在亚 cellular 分辨率并且到踪迹个人神经原和轴突管理了未经触动的鼠标大脑到图象。我们也通过 vertebrae 直接设想了背面的根中心。最后,我们在长骨头的髓空间以内在 3-D 揭示了神经网络的分发模式。这些结果建议 PEGASOS 方法是为一般生物医学的研究的一个有用工具。 | Dian Jing Shiwen Zhang Wenjing Luo Xiaofei Gao Yi Men Chi Ma Xiaohua Liu Yating Yi Abhijit Bugde Bo O. Zhou Zhihe Zhao Quan Yuan Jian Q. Feng Liang Gao Woo-Ping Ge Hu Zhao | 2018 | Cell Research2018，28，8： | 18 |
| 8 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 9 | Impact of chilling injury and global warming on rice yield in Heilongjiang Province显示文摘这研究为米饭集中于索引在 Heilongjiang 省的寒心的损害在 19602009 期间。第一,我们比较了由与传统的方法种密度的米饭加权的一个新导出的气候数据,并且发现新的是更合理的在庄稼收益上估计气候变化的影响。就在第二,寒心的索引由气象学、国家、国际的层次定义的省寒心的米饭的频率和紧张而言被估计。,结果证明气象学的标准对延期类型损害合适国际的,在阀值(GDDn ) 下面种度白天的所谓的和,描绘的最好为米饭的无菌类型的寒心的损害。当二个独立变量到达了约 92% ,包括两损害的米饭收益时间系列模型的解释能力打字(p < 0.05 ) 。最后,我们断定到米饭收益的人和天气因素的贡献率是大约87.2%和12.8%分别地,并且作为光增加的趋势因为无菌类型的寒心的损害在在最近的年里出发到流动时期期间被发现,为在未来在 Heilongjiang 省种的米饭显示高寒心的风险全球温暖。 | LIU Xiaofei ZHANG Zhao SHUAI Jiabing WANG Pin SHI Wenjiao TAO Fulu CHEN Yi | 2013 | Journal of Geographical Sciences2013，23，1： | 16 |
| 10 | The China Multi-Model Ensemble Prediction System and Its Application to Flood-Season Prediction in 2018显示文摘Multi-model ensemble prediction is an effective approach for improving the prediction skill short-term climate prediction and evaluating related uncertainties. Based on a combination of localized operation outputs of Chinese climate models and imported forecast data of some international operational models, the National Climate Center of the China Meteorological Administration has established the China multi-model ensemble prediction system version 1.0 (CMMEv1.0) for monthly-seasonal prediction of primary climate variability modes and climate elements. We verified the real-time forecasts of CMMEv1.0 for the 2018 flood season (June-August) starting from March 2018 and evaluated the 1991-2016 hindcasts of CMMEv1.0. The results show that CMMEv1.0 has a significantly high prediction skill for global sea surface temperature (SST) anomalies, especially for the El Nino-Southern Oscillation (ENSO) in the tropical central-eastern Pacific. Additionally, its prediction skill for the North Atlantic SST triple (NAST) mode is high, but is relatively low for the Indian Ocean Dipole (IOD) mode. Moreover, CMMEv1.0 has high skills in predicting the western Pacific subtropical high (WPSH) and East Asian summer monsoon (EASM) in the June-July-August (JJA) season. The JJA air temperature in the CMMEv1.0 is predicted with a fairly high skill in most regions of China, while the JJA precipitation exhibits some skills only in northwestern and eastern China. For real-time forecasts in March-August 2018, CMMEv1.0 has accurately predicted the ENSO phase transition from cold to neutral in the tropical central-eastern Pacific and captures evolutions of the NAST and IOD indices in general. The system has also captured the main features of the summer WPSH and EASM indices in 2018, except that the predicted EASM is slightly weaker than the observed. Furthermore, CMMEv1.0 has also successfully predicted warmer air temperatures in northern China and captured the primary rainbelt over northern China, except that it predicted much more precipitation in the middle and lower reaches of the Yangtze River than observation. | Hong-Li REN Yujie WU Qing BAO Jiehua MA Changzheng LIU Jianghua WAN Qiaoping LI Xiaofei WU Ying LIU Ben TIAN Joshua-Xiouhua FU Jianqi SUN | 2019 | Journal of Meteorological Research2019，33，3： | 16 |
| 11 | Risk factors and long-term health consequences of macrosomia:a prospective study in Jiangsu Province,China显示文摘We sought to determine risk factors associated with fetal macrosomia and to explore the long-term consequence of infant macrosomia at the age of 7 years.A prospective population based cohort study was designed to examine the associations between maternal and perinatal characteristics and the risk of macrosomia.A nested case-control study was conducted to explore the long-term health consequence of infant macrosomia.The mean maternal age of the macrosomia group was 24.74±3.32 years,which is slightly older than that in the control group(24.35±3.14 years,P = 0.000).The mean maternal body mass index(BMI) at early pregnancy was 22.75±2.81 kg/m 2,which was also higher than that in the control group(21.76±2.59 kg/m 2,P = 0.000).About 64.6% of macrosomic neonates were males,compared with 51.0% in the control group(P = 0.000).Compared with women with normal weight(BMI:18.5-23.9 kg/m 2),women who were overweight(BMI:24-27.9 kg/m 2) or obese(BMI ≥ 28 kg/m 2),respectively,had a 1.69-fold(P = 0.000) and a 1.49-fold(P = 0.000) increased risks of having a neonate with macrosomia,while light weight(BMI<18.5 kg/m 2) women had an approximately 50% reduction of the risk.Furthermore,macrosomia infant had a 1.52-fold and 1.50-fold risk,respectively,of developing overweight or obesity at the age of 7 years(P = 0.001 and P = 0.000).Older maternal age,higher maternal BMI at early pregnancy and male gender were independent risk factors of macrosomia.Macrosomic infant was associated with an increased predisposition to develop overweight or obesity at the beginning of their childhood. | Shouyong Gu Xiaofei An Liang Fang Xiaomin Zhang Chunyan Zhang Jingling Wang Qilan Liu Yanfang Zhang Yongyue Wei Zhibin Hu Feng Chen Hongbing Shen | 2012 | The Journal of Biomedical Research2012，26，4： | 14 |
| 12 | IL-10-producing regulatory B cells restrain the T follicular helper cell response in primary Sjögren’s syndrome显示文摘Increased numbers of T follicular helper(Tfh)cells have been implicated in the development of autoimmune diseases including primary Sjögren’s syndrome(pSS),but how the Tfh cell response is regulated during autoimmune pathogenesis remains largely unclear.Here,we first found negative correlations between IL-10^(+)regulatory B(Breg)cell numbers and Tfh cell responses and disease activity in patients with pSS and mice with experimental Sjögren’s syndrome(ESS).Moreover,we detected high expression of IL-10 receptor on Tfh cells and their precursors in both humans and mice.In culture,IL-10 suppressed human and murine Tfh cell differentiation by promoting STAT5 phosphorylation.By using an adoptive transfer approach and two-photon live imaging,we found significantly increased numbers of Tfh cells with enhanced T cell homing into B cell follicles in the draining cervical lymph nodes of RAG-2−/−mice transferred with IL-10-deficient B cells during ESS development compared with those of RAG-2−/−mice transferred with wild-type B cells.In ESS mice,CD19^(+)CD1d^(hi)CD5^(+)Breg cells with decreased IL-10 production exhibited severely impaired suppressive effects on T cell proliferation.Consistently,CD19^(+)CD24^(+)CD38^(hi) Breg cells from pSS patients showed significantly reduced IL-10 production with defective inhibitory function in the suppression of autologous Tfh cell expansion.Furthermore,the adoptive transfer of IL-10-producing Breg cells markedly suppressed the Tfh cell response and ameliorated ESS progression in ESS mice.Together,these findings demonstrate a critical role for IL-10-producing Breg cells in restraining the effector Tfh cell response during pSS development. | Xiang Lin Xiaohui Wang Fan Xiao Kongyang Ma Lixiong Liu Xiaoqi Wang Dong Xu Fei Wang Xiaofei Shi Dongzhou Liu Yan Zhao Liwei Lu | 2019 | Cellular & Molecular Immunology2019，16，12： | 13 |
| 13 | CAS FGOALS-f3-L Model Datasets for CMIP6 Historical Atmospheric Model Intercomparison Project Simulation显示文摘The outputs of the Chinese Academy of Sciences(CAS) Flexible Global Ocean–Atmosphere–Land System(FGOALS-f3-L) model for the baseline experiment of the Atmospheric Model Intercomparison Project simulation in the Diagnostic,Evaluation and Characterization of Klima common experiments of phase 6 of the Coupled Model Intercomparison Project(CMIP6) are described in this paper. The CAS FGOALS-f3-L model, experiment settings, and outputs are all given. In total,there are three ensemble experiments over the period 1979–2014, which are performed with different initial states. The model outputs contain a total of 37 variables and include the required three-hourly mean, six-hourly transient, daily and monthly mean datasets. The baseline performances of the model are validated at different time scales. The preliminary evaluation suggests that the CAS FGOALS-f3-L model can capture the basic patterns of atmospheric circulation and precipitation well, including the propagation of the Madden–Julian Oscillation, activities of tropical cyclones, and the characterization of extreme precipitation. These datasets contribute to the benchmark of current model behaviors for the desired continuity of CMIP. | Bian HE Qing BAO Xiaocong WANG Linjiong ZHOU Xiaofei WU Yimin LIU Guoxiong WU Kangjun CHEN Sicheng HE Wenting HU Jiandong LI Jinxiao LI Guokui NIAN Lei WANG Jing YANG Minghua ZHANG Xiaoqi ZHANG | 2019 | Advances in Atmospheric Sciences2019，36，8： | 12 |
| 14 | Potentiating CD8^(+) T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling显示文摘Metabolic regulation has been proven to play a critical role in T cell antitumor immunity.However,cholesterol metabolism as a key component of this regulation remains largely unexplored.Herein,we found that the low-density lipoprotein receptor(LDLR),which has been previously identified as a transporter for cholesterol,plays a pivotal role in regulating CD8+T cell antitumor activity.Besides the involvement of cholesterol uptake which is mediated by LDLR in T cell priming and clonal expansion,we also found a non-canonical function of LDLR in CD8+T cells:LDLR interacts with the T-cell receptor(TCR)complex and regulates TCR recycling and signaling,thus facilitating the effector function of cytotoxic T-lymphocytes(CTLs).Furthermore,we found that the tumor microenvironment(TME)downregulates CD8+T cell LDLR level and TCR signaling via tumor cell-derived proprotein convertase subtilisin/kexin type 9(PCSK9)which binds to LDLR and prevents the recycling of LDLR and TCR to the plasma membrane thus inhibits the effector function of CTLs.Moreover,genetic deletion or pharmacological inhibition of PCSK9 in tumor cells can enhance the antitumor activity of CD8+T cells by alleviating the suppressive effect on CD8+T cells and consequently inhibit tumor progression.While previously established as a hypercholesterolemia target,this study highlights PCSK9/LDLR as a potential target for cancer immunotherapy as well. | Juanjuan Yuan Ting Cai Xiaojun Zheng Yangzi Ren Jingwen Qi Xiaofei Lu Huihui Chen Huizhen Lin Zijie Chen Mengnan Liu Shangwen He Qijun Chen Siyang Feng Yingjun Wu Zhenhai Zhang Yanqing Ding Wei Yang | 2021 | Protein & Cell2021，12，4： | 12 |
| 15 | Enhancement of room-temperature magnetoresistance in La_(0.5)Sm_(0.2)Sr_(0.3)MnO_3/(Ag_2O)_(x/2)显示文摘La0.5Sm0.2Sr0.3MnO3/(Ag2O)x/2 (x = 0.00, 0.04, 0.08, 0.25, 0.30) samples were prepared by the solid-state reaction method, and their transport behaviors, transport mechanism, and magnetoresistance effect were studied through the measurement and fitting of ρ-T curves. The results show that the element Ag takes part in reaction when the doping amount is small. Ag is mainly distributed at the grain boundary of the host material and is in metallic state when the doping amount is relatively large; then the system becomes a two-phase composite. A small amount of Ag doping can apparently increase grain-boundary magnetoresistance induced by the spin-dependent scattering. The resistivity of the sample doped with 30 mol% Ag is one order of magnitude smaller than that of low-doped samples, and its magnetoresistance in the magnetic field of 0.5 T and at 300 K is strengthened apparently reaching 9.4%, which is connected not only with the improvement of the grain-boundary structure of the host material but also with the decrease of material resistivity. | PENG Zhensheng WANG Guiying TANG Yonggang LIU Peng NIU Xiaofei | 2010 | Rare Metals2010，29，1： | 10 |
| 16 | Potential Benefits of Biochar in Agricultural Soils:A Review显示文摘Soil degradation,characterized by declines in nutrient status and simultaneous accumulation of pesticide residues,is a major problem affecting agricultural ecosystems.Previous studies indicate that biochar application to soil has promise as a practical method to alleviate these pressures:increasing crop yield and enhancing pesticide degradation.Here,we review the roles of biochar in both chemical and biological promotion of pesticide degradation and the potential benefits of biochar relating to the efficiency of fertilizer use,availability of nutrients,and nutrient exchange.Biochar typically has a high surface area featuring many functional groups,a high cation exchange capacity,and high stability.Major factors that impact on the nutrient retention characteristics of biochar(e.g.,feedstock,pyrolysis temperature,and application rate) are also discussed herein.Nonetheless,more studies of the long-term impacts on soil properties from biochar addition are still required before it can be possible to accurately quantify the sustainability of this approach to sequester carbon and restore soil function. | DING Yang LIU Yunguo LIU Shaobo HUANG Xixian LI Zhongwu TAN Xiaofei ZENG Guangming ZHOU Lu | 2017 | Pedosphere2017，27，4： | 10 |
| 17 | Field Capacity in Black Soil Region, Northeast China显示文摘In this work, 23 black soil profiles were surveyed and 113 soil samples were collected to determine the field capacity (FC) of the black soil in Northeast China. The effectiveness of three methods measuring FC, the Wilcox method (WM), the undisturbed soil pressure plate method (PUM) and the air-dried sieved soil pressure plate method (PDM) were compared to select a suitable laboratory measurement method. Results show that the FC values measured by PDM are greater than those measured by PUM, and the values measured by PUM are greater than those measured by WM. PUM is more suitable for the determination of FC in the study area. One regression equation between PUM and PDM has been established through which undisturbed soil can be replaced by air-dried sieved soil, which is easier to get, to measure FC. FCs vary from 23.50% to 37.00%, with an average of 31.65%, which differ greatly among the 23 black soil profiles. FC is found to be significantly positively correlated with the silt content, clay content and bulk density of the soil, but significantly negatively correlated with the sand content. An empirical pedotransfer function is established to estimate the FC using available soil physical and chemical properties. | DUAN Xingwu XIE Yun LIU Gang GAO Xiaofei LU Hongmei | 2010 | Chinese Geographical Science2010，20，5： | 9 |
| 18 | Bayesian discriminant analysis for prediction of coal and gas outbursts and application显示文摘Based on the principle of Bayesian discriminant analysis, we established a model of Bayesian discriminant analysis for predicting coal and gas outbursts. We selected five major indices which affect outbursts, i.e., initial speed of methane diffusion, a consistent coal coefficient, gas pressure, destructive style of coal and mining depth, as discriminating factors of the model. In our model, we divided the type of coal and gas outbursts into four grades regarded as four normal populations. We then obtained the corresponding discriminant functions through training a set of data from engineering examples as learning samples and evaluated their criteria by a back substitution method to verify the optimal properties of the model. Finally, we applied the model to the prediction of coal and gas outbursts in the Yunnan Enhong Mine. Our results coincided completely with the actual situation. These results show that a model of Bayesian discriminant analysis has excellent recognition performance, high prediction accuracy and a low error rate and is an effective method to predict coal and gas outbursts. | WANG Chao WANG Enyuan XU Jiankun LIU Xiaofei LING Li | 2010 | Mining Science and Technology2010，20，4： | 9 |
| 19 | microRNA-mediated R gene regulation: molecular scabbards for double-edged swords显示文摘Plant resistance(R) proteins are immune receptors that recognize pathogen effectors and trigger rapid defense responses, namely effector-triggered immunity. R protein-mediated pathogen resistance is usually race specific. During plant-pathogen coevolution,plant genomes accumulated large numbers of R genes. Even though plant R genes provide important natural resources for breeding disease-resistant crops, their presence in the plant genome comes at a cost. Misregulation of R genes leads to developmental defects, such as stunted growth and reduced fertility. In the past decade, many microRNAs(miRNAs) have been identified to target various R genes in plant genomes. miRNAs reduce R gene levels under normal conditions and allow induction of R gene expression under various stresses. For these reasons, we consider R genes to be double-edged 'swords' and miRNAs as molecular 'scabbards'. In the present review, we summarize the contributions and potential problems of these 'swords' and discuss the features and production of the 'scabbards', as well as the mechanisms used to pull the 'sword' from the 'scabbard'when needed. | Yingtian Deng Minglei Liu Xiaofei Li Feng Li | 2018 | Science China(Life Sciences)2018，61，2： | 9 |
| 20 | CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells显示文摘 | Yongping Zhang Xingying Zhang Chen Cheng Wei Mu Xiaojuan Liu Na Li Xiaofei Wei Xiang Liu Changqing Xia Haoyi Wang | 2017 | Frontiers of Medicine2017，11，4： | 9 |
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