Stimulus-responsive polymeric nanoparticles for biomedical applications

查看全文 作　　者：LI YongYong1,2,DONG HaiQing1,2,WANG Kang1,SHI DongLu 2,ZHANG XianZheng1 & ZHUO RenXi1 1Key Laboratory of Biomedical Polymers,Ministry of Education;Department of Chemistry,Wuhan University,Wuhan 430072,China;2Institute for Advanced Materials and Nano Biomedicine(iNANO),Tongji University,Shanghai 200092,China

出　　处：《Science China Chemistry》索引2010年第53卷第3期,共11页

基　　金：supported by the National Key Basic Research Program of China (Grant No 2005CB623903);the National Natural Science Foundation of China (Grant No 50633020);the Program for Young Excellent Talents in Tongji University,the Special Project of Shanghai Nanotechnology (Grant No 0952nm04800);Natural Science Foundation of Shanghai (Grant No 10ZR1432100) 摘　　要：Polymeric nanoparticles with unique properties are regarded as the most promising materials for biomedical applications including drug delivery and in vitro/in vivo imaging.Among them,stimulus-responsive polymeric nanoparticles,usually termed as 'intelligent' nanoparticles,could undergo structure,shape,and property changes after being exposed to external signals including pH,temperature,magnetic field,and light,which could be used to modulate the macroscopical behavior of the nanoparticles.This paper reviews the recent progress in stimulus-responsive nanoparticles used for drug delivery and in vitro/in vivo imaging,with an emphasis on double/multiple stimulus-responsive systems and their biomedical applications. 关键词：polymer stimulus-responsive nanoparticles DRUG CARRIER cellular imaging

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Stimulus-responsive polymeric nanoparticles for biomedical applications

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