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Even low-grade inflammation impacts on small intestinal function

查看全文 作  者:Katri [1,2]Peuhkuri;Heikki [1]Vapaatalo;Riitta [1,3]Korpela 高影响力作者 机构地区:[1]Institute of Biomedicine,University of Helsinki;[2]Netnut Nutrition Information Services Company;[3]Valio Research Centre,PO Box 30,FI-00039 Helsinki,Finland高影响力机构 出  处:《World Journal of Gastroenterology》索引2010年第16卷第9期,共6页高影响力期刊 摘  要:Independent of the cause and location,inflammation-even when minimal-has clear effects on gastrointestinal morphology and function.These result in altered digestion,absorption and barrier function.There is evidence of reduced villus height and crypt depth,increased permeability,as well as altered sugar and peptide absorption in the small intestine after induction of inflammation in experimental models,which is supported by some clinical data.Identification of inflammatory factors which may promote the process of gastrointestinal dysfunction as well as clinical research to verify experimental observations of inflammatory modulation of gastrointestinal function are required.Moreover,nutritional strategies to support functional restitution are needed. 关 键 词:Small INTESTINE DIGESTION Absorption MOTILITY Permeability LOW-GRADE inflammation CYTOKINES
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