A new facile approach to N-alkylpyrroles from direct redox reaction of 4-hydroxy-L-proline with aldehydes

查看全文 作　　者：ZOU [1]ZhiQin;DENG [1]ZeJun;YU [1]XinHong;ZHANG [1]ManMan;ZHAO [2]SiHan;LUO [1]Ting;YIN [1]Xin;XU [1]HUi;WANG [1,2]Wei 机构地区：[1]School of Pharmacy,Easy China University of Science&Technology,Shanghai 200237,China;[2]Department of Chemistry&Chemical Biology,University of New Mexico,MSC032060,NM 87131,USA 出　　处：《Science China Chemistry》索引2012年第55卷第1期,共7页 基　　金：support from the National Natural Science Foundation of China(20972051);the Science and Technology Commission of Shanghai Municipality(08430703900 & 08431901800);the 111 Project(B07023);East China University of Science & Technology 摘　　要：An unprecedented acetic acid-catalyzed efficient access to N-alkylpyrroles from reaction of 4-hydroxy-L-proline with a variety of aldehydes has been achieved in good to excellent yields under mild reaction conditions. 关 键 词：氧化还原反应 L-脯氨酸 羟基 简便 醛 反应条件