Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages

查看全文 作　　者：Xianfa [1,2]Yang;Boqiang [3]Hu;Yu [3]Hou;Yunbo [1,4]Qiao;Ran [1]Wang;Yingying [1]Chen;Yun [1]Qian;Su [1]Feng;Jun [1,5]Chen;Chang [1]Liu;Guangdun [1]Peng;Fuchou [3,6,7]Tang;Naihe [1,2]Jing

机构地区：[1]State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and CellBiology, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai 200031, China;[2]School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;[3]Beijing Advanced Innovation Center for Genomics (ICG) and Biomedical Institute for Pioneering Investigation via Convergence,College of Life Sciences, Peking University, Beijing 100871, China;[4]Precise Genome Engineering Center, School of Life Sciences,Guangzhou University, Guangzhou, Guangdong 510006, China;[5]Department of Genetics and Cell Biology, College of Life Sciences,Nankai University, Tianjin 300071, China;[6]Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing 100871,China;[7]Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China

出　　处：《Cell Research》索引2018年第28卷第5期,共4页

基　　金：This work was supported in part by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA16020501 and XDA16020404), the National Key Basic Research and Development Program of China (2017YFA0102700, 2014CB964804, and 2015CB964500), and the National Natural Science Foundation of China (31430058, 31571513, 31630043, 31501178, 91519314, 31661143042, 81561138005, 3162501.8, and 81521002). 关键词：胚胎 DNA 基因粘性哺乳动物房间接合子 ICM

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Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages

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