Hydrophilic surface modification of PDMS for droplet microfluidics using a simple,quick,and robust method via PVA deposition

查看全文 作　　者：Tatiana [1]Trantidou;Yuval [1,2]Elani;Edward [3]Parsons;Oscar [1,2]Ces

机构地区：[1]Department of Chemistry,Imperial College London,London SW72AZ,UK;[2]Institute of Chemical Biology,Imperial College London,London SW72AZ,UK;[3]London Centre for Nanotechnology,University College London,London WC1E 6BT,UK

出　　处：《Microsystems & Nanoengineering》索引2017年第3卷第1期,共9页

基　　金：This work was supported by the EPSRC(grants EP/K038648/1 and EP/J017566/1);by an EPSRC Fellowship awarded to YE(grant EP/N016998/1). 摘　　要：Polydimethylsiloxane(PDMS)is a dominant material in the fabrication of microfluidic devices to generate water-in-oil droplets,particularly lipid-stabilized droplets,because of its highly hydrophobic nature.However,its key property of hydrophobicity has hindered its use in the microfluidic generation of oil-in-water droplets,which requires channels to have hydrophilic surface properties.In this article,we developed,optimized,and characterized a method to produce PDMS with a hydrophilic surface via the deposition of polyvinyl alcohol following plasma treatment and demonstrated its suitability for droplet generation.The proposed method is simple,quick,effective,and low cost and is versatile with respect to surfactants,with droplets being successfully generated using both anionic surfactants and more biologically relevant phospholipids.This method also allows the device to be selectively patterned with both hydrophilic and hydrophobic regions,leading to the generation of double emulsions and inverted double emulsions. 关键词：double emulsions droplet microfluidics HYDROPHOBIC HYDROPHILIC PDMS surface modification

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Hydrophilic surface modification of PDMS for droplet microfluidics using a simple,quick,and robust method via PVA deposition

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