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Identification of differentially expressed genes and signaling pathways in neutrophils during sepsis-induced immunosuppression via bioinformatics analysis

查看全文 作  者:Yongxin [1]Zheng;Zhihui [1]Zhang;Yongbo [1]Huang;Jinping [2]Wang;Ling [1]Sang;Yonghao [1]Xu;Xiaoqing [1]Liu;Yimin [1]Li 高影响力作者 机构地区:[1]Department of Pulmonary and Critical Care Medicine,State Key Laboratory of Respiratory Diseases,Guangzhou Institute of Respiratory Health,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510000,China;[2]Department of Cardiovascular Medicine,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510000,China高影响力机构 出  处:《Chinese Medical Journal》索引2022年第135卷第17期,共3页高影响力期刊 基  金:This study was supported by the National Natural Science Foundation of China(Nos.NSFC 81870069,81970071,81770077and 82070084);the Natural Science Foundation of Guangdong Province(Nos.2017A030313781 and 2020A1515011459). 摘  要:To the Editor:Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection.Sepsis deeply perturbs immune homeostasis,and impairs innate and adaptive immunity by directly altering the lifespan,production,and function of the effector cells responsibie for homeostasis. 关 键 词:HOMEOSTASIS IMMUNITY analysis
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