Synchronized ventilation during resuscitation in pigs does not necessitate high inspiratory pressures to provide adequate oxygenation

查看全文 作　　者：Miriam [1]Renz;Raphael RenéCinto [1]Noack;[1]RenéRissel;Katja [1]Mohnke;Julian [1]Riedel;Bastian [1]Dunges;Alexander [1]Ziebart;Erik Kristoff er [1]Hartmann;Robert [1]Rummler 机构地区：[1]Department of Anesthesiology,University Medical Center,Johannes Gutenberg University,Mainz 55131,Germany 出　　处：《World Journal of Emergency Medicine》索引2023年第14卷第5期,共4页 基　　金：funded by internal university research funding of the University Medical Center Mainz granted personal to Miriam Renz as well as a personal grant of the German Research Foundation to Robert Ruemmler (RU 2371/1)。 摘　　要：The optimal ventilation method for patients suffering from cardiac arrest and receiving cardiopulmonary resuscitation(CPR)remains unclear,and the recent guidelines do not provide detailed information.[1-3]During CPR,changing thoracic pressures due to chest compressions and ventilation pressure infl uence venous return and cardiac output,respectively.[4-6]Novel mechanical ventilation modes that are synchronized to chest compressions may improve blood flow and oxygenation.[4]In this porcine trial,we investigated the feasibility of a specially designed chest compression synchronized ventilation(CCSV)mode with peak pressures limited to 40 mbar(1 mbar=0.1 kPa)and an experimental synchronized ventilation(SV)limited to 20 mbar,respectively,intended to achieve a more lung-protective ventilation pattern during resuscitation.We evaluated whether the diff erent synchronized pressure levels ameliorate hemodynamics,gas exchange and pulmonary function and compared it to intermittent positive pressure ventilation(IPPV). 关 键 词：RESUSCITATION protective CARDIAC