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| 1 | Vitamin D status and viral response to therapy in hepatitis C infected children显示文摘AIM: To study the frequency of vitamin D deficiency in patients with hepatitis C virus(HCV) infection and to evaluate the role of vitamin D supplementation in improving antiviral therapy.METHODS: Sixty-six children aged from 7-14 years(mean ± SD, 11.17 ± 2.293) diagnosed with HCV infection were matched to 28 healthy controls. Serum levels of 25(OH) D3, calcium, phosphorus, alkaline phosphatase and plasma level of parathormone were measured. Quantitative PCR for HCV was performed Bone density was determined by dual energy X-ray absorptiometry. All cases received conventional therapy, and only 33 patients received vitamin D supplementation.RESULTS: Children with HCV showed significantly increased levels of HCV RNA(P < 0.001), parathormone(P < 0.01) and decreased vitamin D levels(P < 0.05)(33.3% deficient and 43.3% insufficient) compared with controls. Abnormal bone status(Z score-1.98 ± 0.75) was found in ribs, L-spine, pelvis and total body. Cases treated with vitamin D showed significant higher early(P < 0.04) and sustained(P < 0.05) virological response. There was a high frequency of vitamin D deficiency among the Egyptian HCV children, with significant decrease in bone density. The vitamin D level should be assessed before the start of antiviral treatment with the correction of any detected deficiency. CONCLUSION: Adding vitamin D to conventional Peg/RBV therapy significantly improved the virological response and helped to prevent the risk of emerging bone fragility. | Azza A Eltayeb Madleen Adel A Abdou Amal M Abdel-aal Mostafa H Othman | 2015 | World Journal of Gastroenterology2015，21，4： | 3 |
| 2 | Study of fully developed, liquid-metal, open-channel flow in a nearly coplanar magnetic field 显示文摘 | Morley N B Abdou M A | 1997 | Fusion Technology1997，31，： | 2 |
| 3 | On the numerical solutions of Fredholm-Volterra integral equation显示文摘 | Abdou M A Mohamed K I Ismail A S | 2003 | Applied Mathematics and Computation2003，146，： | 1 |
| 4 | Variational Iteration Method for Solving Burger's and Coupled Burger's Equations 显示文摘 | Abdou M A Soliman A A | 2005 | J Comput Appl Math2005，181，2： | 1 |
| 5 | Novel antibacterial lactoferrin peptides generated by rennet digestion and autofocusing technique 显示文摘 | Hend A Elbarbary Adham M Abdou EunYoung Park | 2010 | International Dairy Journal2010，，20： | 1 |
| 6 | Chapman-enskog-maximum entropy method on time-dependent neutron transport equation显示文摘 | ABDOU M A | 2006 | Journal of Quantitative Spectroscopy and Radiative Transfer2006，101，2： | 1 |
| 7 | The extended F-expansion method and its application for a class of nonlinear evolution equations显示文摘 | Abdou M A | 2007 | Chaos Solitons and Fractals2007，31，： | 1 |
| 8 | Antimi-crobial activities of Allium sativum,Allium cepaa,Raphanussativus,Capsicum frutescens,Eruca sativa,Allium kurrat onbacteria显示文摘 | Abdou I A Abou-Zeid A A El-Sherbeeny M R | 1972 | Qual Plant Mater Veg1972，22，： | 1 |
| 9 | Assessment of monitored energy use and thermal comfort conditions in mosques in hot-humid climates 显示文摘 | MOHAMM ADS A + Homoud ADEL A Abdou I SM AIL M Bu- daiw i | 2009 | Energy and Buildings2009，41，6： | 1 |
| 10 | 3 D MHD free surface fluid flow simulation based on magnetic - field induction equations显示文摘 | Huang H L Ying A Abdou M A | | Fusion Engineering and Design0，22，6364： | 1 |
| 11 | Progress on an integrated multi-physics simulation predictive capability for plasma chamber nuclear components显示文摘 | Ying A Abdou M Zhang H Munipalli R Ulrickson M Sawan M Merrill B | 2010 | Fusion Engineering and Design2010，85，79： | 1 |
| 12 | The extended Fan sub-equation method and ils applications for a class of nonlinear evolution equations显示文摘 | ELWAKIL S A ABDOU M A | 2008 | Chaos Solitons and Fractals2008，36，2： | 1 |
| 13 | On the numerical solutions of Fredholm-Volterra integral equation显示文摘 | Abdou M A Mohamed K I Ismail A S | 2003 | Applied Mathematics and Computation2003，146，： | 1 |
| 14 | Antimicrobial peptides derived from hen egg lysozyme with inhibitoryeffect against Bacillus species显示文摘 | ABDOU A M HIGASHIGUCHI S ABOUELEININ A M | 2007 | Food Control2007，18，2： | 1 |
| 15 | Study of fully developed, liquidmetal , open-channel flow in a nearly coplanar magnetic field显示文摘 | Morley N B Abdou M A | 1997 | Fusion Technology1997，31，： | 1 |
| 16 | Cyclooxygenase-2 expression in chronic gastritis and gastric carcinoma, correlation with prognostic parameters 显示文摘 | SAMAKA R M ABDOU A G ABD EL-WAHED M M | 2006 | J Egypt Natl Canc Inst2006，18，4： | 1 |
| 17 | A bridge between projeetic methods and simple type methods for incompressib Navier-Stokes equations显示文摘 | NI M J ABDOU M A | 2007 | International Journal fc Numerical Methods in Engineering2007，72，12： | 1 |
| 18 | Antimicrobial peptides derived from hen egg lysozyme with inhibitory effect against Bacillus species 显示文摘 | Abdou A M Higashiguchi S Aboueleinin A M | 2007 | Food Control2007，18，17： | 1 |
| 19 | Exploring liquid metal plasma facing component (PFC) concepts liquid metal film flow behavior under fusion relevant magnetic fields 显示文摘 | Narula M Abdou M A Ying A | 2006 | Fusion Engineering and Design2006，81，： | 1 |
| 20 | Blanket material and engineering issues, and requirements for experiments and facilities显示文摘 | Abdou M A Gierszewski P Tillack M S | 1986 | Journal of Nuclear Materials1986，14，： | 1 |
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