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| 1 | Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation显示文摘Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated. Most concerning, how ever, are the associated harmful side effects, often unrecognized by consumers. Garcinia cambogia extract and Garcinia cambogia containing products are some of the most popular dietary supplements currently marketed for weight loss. Here, we report the first known case of fulminant hepatic failure associated with this dietary supplement. One active ingredient in this supplement is hydroxycitric acid, an active ingredient also found in weight-loss supplements banned by the Food and Drug Administration in 2009 for hepatotoxicity. Heightened awareness of the dangers of dietary supplements such as Garcinia cambogia is imperative to prevent hepatoxicity and potential fulminant hepatic failure in additional patients. | Keri E Lunsford Adam S Bodzin Diego C Reino Hanlin L Wang Ronald W Busuttil | 2016 | World Journal of Gastroenterology2016，22，45： | 3 |
| 2 | Evolving role of magnetic resonance techniques in primary sclerosing cholangitis显示文摘Development of non-invasive methods to risk-stratify patients and predict clinical endpoints have been identified as one of the key research priorities in primary sclerosing cholangitis(PSC). In addition to serum and histological biomarkers, there has been much recent interest in developing imaging biomarkers that can predict disease course and clinical outcomes in PSC.Magnetic resonance imaging/magnetic resonance cholangiopancreatography(MRI/MRCP) continue to play a central role in the diagnosis and follow-up of PSC patients. Magnetic resonance(MR) techniques have undergone significant advancement over the last three decades both in MR data acquisition and interpretation. The progression from a qualitative to quantitative approach in MR acquisition techniques and data interpretation, offers the opportunity for the development of objective and reproducible imaging biomarkers that can potentially be incorporated as an additional endpoint in clinical trials. This review article will discuss how the role of MR techniques have evolved over the last three decades from emerging as an alternative diagnostic tool to endoscopic retrograde cholangiopancreatography, to being instrumental in the ongoing search for imaging biomarker of disease stage, progression and prognosis in PSC. | Emmanuel A Selvaraj Emma L Culver Helen Bungay Adam Bailey Roger W Chapman Michael Pavlides | 2019 | World Journal of Gastroenterology2019，25，6： | 2 |
| 3 | Calculation of the effects of protonation on rigid-rod polymers显示文摘 | Farmer B L Dudis D S Adams W W | 1994 | Polymer1994，35，17： | 1 |
| 4 | Adenoviral mediated interferon-alpha 2b gene therapy suppresses the pro-angiogenic effect of vascular endothelial growth factor in superficial bladder cancer显示文摘 | Adam L Black PC Kassouf W | 2007 | J U rol2007，177，5： | 1 |
| 5 | Molecular dynamics simulations of consolidation processes during fabrication of nanophase palladium显示文摘 | Liu C L Adams J B Siegal R W | 1994 | Nanostructured Materials1994，4，4： | 1 |
| 6 | The assessment of trust orientation显示文摘 | Couch L L Adams J M Jones W H | 1996 | Journal of Personality Assessment1996，67，2： | 1 |
| 7 | miR-200expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy显示文摘 | Adam L Zhong M Choi W | 2009 | Clin Cancer Res2009，15，16： | 1 |
| 8 | Design,Synthesis,and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Indol5-yl)-1-Methyl-1 H-Pyrrole-2-Carbonitrile (WAY-255348)显示文摘 | Fensome A Adams W R Adams A L | | 0，，： | 1 |
| 9 | The effect of chlorhexidine on defined, mixed culture oral biofilms grown in a novel model system显示文摘 | Kinniment S L Wimpenny J W T Adams D | 1996 | JAppl Bacterio1996，181，： | 1 |
| 10 | Effect of a chemical additive on Salmonella in poultry feed and host birds显示文摘 | WESTERFIELD B L ADAMS A W ERVIN L E | 1970 | Poult Sci1970，49，： | 1 |
| 11 | MPA and MPP Students: Twins, Siblings, or Distant Cousins? 显示文摘 | INFELD D L ADAMS W C | 2011 | Journal of Public Affairs Education2011，17，2： | 1 |
| 12 | Optical absorption and emission of LiYF4 : Pr3+ 显示文摘 | J L Adam W A Sibley D R Gabbe | 1985 | Journal of Luminescence1985，33，4： | 1 |
| 13 | An FGF21-adi poneetin-ceramide axis controls energy expenditure and insulin ac- tion in mice显示文摘 | Holland W L Adams A C Brozinick JT | 2013 | Cell Metabolism2013，17，5： | 1 |
| 14 | Osteoblastic cells regulate the haematopoietic stem cell niche 显示文摘 | CALVI L M ADAMS G B WEIBRECHT K W | 2003 | Nature2003，425，6960： | 1 |
| 15 | Human pathogenic viruses at sewage sludge disposal sites in the Middle Atlantic region 显示文摘 | GOYAL S M ADAMS W N OMALLEY M L | 1984 | Appl Environ Microbiol1984，48，： | 1 |
| 16 | Alkylphenol ethoxylates in the environment显示文摘 | Naylor C G Mieure J P Adams W J Weeks J A Castaldl F J Ogle L D Romano R R | 1992 | American Oil Chemists Society1992，69，： | 1 |
| 17 | Osteoblastic cells regulate the haematopoietic stem cell niche显示文摘 | Calvi L M Adams G B Weibrecht K W | 2003 | Nature2003，425，6960： | 1 |
| 18 | Coumarins from Cnidium monnieri and their antiosteoporotic activity显示文摘 | Zhang Q Qin L He W Van Puyvelde L Maes D Adams A Zheng H De Kimpe N | 2007 | Planta Med2007，73，1： | 1 |
| 19 | miR-200 expression regulatesepithelial-to-mesenchymal transition in bladder cancer cells andreverses resistance to epidermal growth factor receptor therapy显示文摘 | Adam L Zhong M Choi W | 2009 | Clin Cancer Res2009，15，： | 1 |
| 20 | The use of specific gravity and its reciprocal in predicting the carcass composition of pigs slaughtered at three weights显示文摘 | Smith W C | 1964 | Anim Prod1964，6，： | 1 |
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