|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pyruvate-fortified resuscitation stabilizes cardiac electrical activity and energy metabolism during hypovolemia显示文摘AIM: To test the hypothesis that fluid resuscitation with Ringer's solution enriched with pyruvate(PR), a physiological antioxidant and energy substrate, affords protection of myocardial metabolism and electrophysiological performance superior to lactated Ringer's(LR) during hypovolemia and hindlimb ischemia-reperfusion.METHODS: Male domestic goats(25-30 kg) were exsanguinated to a mean arterial pressure of 48 ± 1 mm Hg. Right hindlimb ischemia was imposed for 90 min by applying a tourniquet and femoral crossclamp. LR or PR, infused iv, delivered 0.05 mmol/kg per minute L-lactate or pyruvate, respectively, from 30 min hindlimb ischemia until 30 min post-ischemia. Time controls(TC) underwent neither hemorrhage, hindlimb ischemia nor resuscitation. Goats were sacrificed and left ventricular myocardium biopsied at 90 min fluid resuscitation(n = 6 per group) or 3.5 h later(n = 9 LR, 10 PR, 8 TC).RESULTS: Myocardial 8-isoprostane content, phosphocreatine phosphorylation potential, creatine kinase activity, and heart rate-adjusted QT interval(QTc) vari- ability were evaluated at 90 min resuscitation and 3.5 h post-resuscitation. PR sharply lowered pro-arrhythmic QTc variability vs LR(P < 0.05); this effect persisted 3.5 h post-resuscitation. PR lowered myocardial 8-isoprostane content, a product of oxidative stress, by 39 and 37% during and 3.5 h after resuscitation, respectively, vs LR. Creatine kinase activity fell 42% post-LR vs TC(P < 0.05), but was stable post-PR(P < 0.02 vs post-LR). PR doubled phosphocreatine phosphorylation potential, a measure of ATP free energy state, vs TC and LR(P < 0.05); this energetic enhancement persisted 3.5 h post-resuscitation.CONCLUSION: By augmenting myocardial energy state and protecting creatine kinase activity, pyruvateenriched resuscitation stabilized cardiac electrical function during central hypovolemia and hindlimb ischemiareperfusion. | Hunaid A Gurji Daniel W White Besim Hoxha Jie Sun Albert H Olivencia-Yurvati Robert T Mallet | 2013 | World Journal of Critical Care Medicine2013，2，4： | 3 |
| 2 | Kontrastmittelsonografie bei B-Bild-morphologisch unklaren Leberraumforderungen – Diagnostische Treffsicherheit im klinischen Alltag (DEGUM-Multicenter – Studie)显示文摘 | D Strobel K Seitz W Blank A Schuler C Dietrich A Herbay M Friedrich-Rust G Kunze D Becker U Will W Kratzer F Albert C Pachmann K Dirks H Strunk C Greis T Bernatik | 2008 | Ultraschall in Med2008，，05： | 2 |
| 3 | Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘 | Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R | 2009 | Journal of Bacteriology2009，191，16： | 1 |
| 4 | Application of fluid dynamic gauging to annular test apparatuses for studying fouling and cleaning显示文摘 | GU T ALBERT F AUGUSTIN W | 2011 | Experimental Thermal and Fluid Science2011，35，3： | 1 |
| 5 | Anthocyanin/ polyphenolic-rich fruit juice reduces oxidative cell damage in an intervention study with patients on hemodialysis显示文摘 | Spormann T M Albert F W Rath T | 2008 | Cancer epidemiology biomarkers & pre- vention2008，17，12： | 1 |
| 6 | Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) 显示文摘 | O'CONNOR C M ABRAHAM W T ALBERT N M | 2008 | Am Heart J2008，156，4： | 1 |
| 7 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 8 | A paleoclimate model of northern hemisphere ice sheets 显示文摘 | Birchfied G E Johannes W Albert T L | 1981 | Quaternary Research1981，15，2： | 1 |
| 9 | Implementation of comfort-based air- handling unit control algorithms显示文摘 | Tse W L Albert T P | 2000 | ASHRAE Transactions2000，106，1： | 1 |
| 10 | Association between performance measures and clinical outcomes for patients hospitalized with heart failure显示文摘 | FONAROW G C ABRAHAM W T ALBERT N M | 2007 | JAMA2007，297，1： | 1 |
| 11 | Electromigration-induced mierostructure evolution in tin studied by synchrotron X-ray microdiffractiou 显示文摘 | ALBERT T W TU K N LLOYD J R | 2004 | Appl Phys Lett2004，85，13： | 1 |
| 12 | Threshold selection using a minimal histogram entropy difference显示文摘 | Sahoo P K Slaaf D W Albert T A | | 0，，： | 1 |
| 13 | Controlled llinicd trial of methylpredmisokone in patients with chronic bronchitis and acue respiratorg insufficiency显示文摘 | Albert R K Martin T R Lewis S W | 1980 | Ann Intern Med1980，92，6： | 1 |
| 14 | The P0 gene of Sugarcane yellow leaf virus encodes an RNA silencing suppressor with unique activities显示文摘 | Mangwende T Wang M L Borth W Hu J Moore P H Mirkov T E and Albert H H | | 0，，： | 1 |
| 15 | Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure findings from the OPTIMIZE-HF program显示文摘 | FONAROW G C ABRAHAM W T ALBERT N M | 2008 | J Am Coll Cardiol2008，52，： | 1 |
| 16 | The draft genome of the transgenic tropical fruit tree papaya (Caricapapaya Linnaeus)显示文摘 | Ming R Hou S Feng Y Yu Q Dionne-Laporte A Saw J H Senin P Wang W Ly B V Lewis K L Salzberg S L Feng L Jones M R Skelton R L Murray J E Chen C Qian W Shen J Du P Eustice M Tong E Tang H Lyons E Paull R E Michael T P Wall K Rice D W Albert H Wang M L Zhu Y | | 0，，： | 1 |
| 17 | An Artificial Neuralnetwork Based Traffic Patterns Recognition Systems显示文摘 | Albert T P Beebe J R Chan W L | 1996 | International Journal of Elevator Engineering1996，，1： | 1 |
| 18 | The draft genome of the transgenic tropical fruit tree papaya (Caricapapaya Linnaeus) 显示文摘 | MING R HOU S FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L SALZBERG S L FENG L JONES M R SKELTON R L MURRAY J E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WA1 C M ACKERMAN C M REN Y LIU C WANG J WANG J NA J K SHAKIROV E V HAAS B THIMMAPURAM I NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS- P?REZ R TORRES M J FELTUS FA PORTER B LI Y BURROUGHS A M LUO MC LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E DEPAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 19 | Threshold selection using a minimal histogram entropy different显示文摘 | SAHOO P K SLAAF D W ALBERT T A | 1997 | Optical Engineering1997，36，7： | 1 |
| 20 | Comparison on linear synchronous motors and conventional rotary motors driven wire-EDM processes 显示文摘 | ALBERT W J Hsue YAN M T KE S H | 2007 | Journal of Materials Processing Technology2007，，192193： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员