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| 1 | Synthesis of a copolymer carrier for anticancer drug luteolin for targeting human breast cancer cells显示文摘OBJECTIVE: To focus a new chemoprevention approach that uses nanotechnology to deliver luteolin to human breast cancer cells(MCF-7), and its underlying mechanism.METHODS: Water-soluble copolymer-encapsulated nanoparticle-luteolin(CENL) was formulated using the hydrophobic drug luteolin. The ability to load and release he anticancer drug into/from the synthesized hyperbranched polyester was evaluated by high-performance liquid chromatography.The successful synthesis of CENL was supported by analytical techniques including fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, gel permeation chromatography,and dynamic light scattering. Cell viability was measured using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide color method. Reactive oxygen species(ROS) were measured using a dichlorofluorescein probe and intracellular calcium(Cai2+) was evaluated with a flu3-AM probe.RESULTS: The results showed that the drug delivery system is stable and that the loading capacity is high. Treatment with nanoparticles containing luteolin and free luteolin resulted in cell death in breast cancer cells at high concentrations (IC50(33 ± 4) and(48 ± 6) μM, respectively)At high concentrations,CENL reduced cell viability and increased ROS and Cai2+ production.CONCLUSION: Our results demonstrate that CENL has potential for human breast cancer treatment. | Mahin Maleki Ali Aidy Elahe Karimi Shaahin Shahbazi Nader Safarian Naser Abbasi | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 2 |
| 2 | Ballistic impact properties of woven bamboo-woven E-glass-unsaturated polyester hybrid composites显示文摘In this study, a laminated woven bamboo/woven E glass/unsaturated polyester composite is developed to combat a ballistic impact from bullet under shooting test. The aim of this study is to understand the fundamental effects of the woven bamboo arrangement towards increasing ballistic resistance properties. The work focusses on the ballistic limit test known as NIJ V50, which qualifies materials to be registered for use in combat armor panels. The results show that the composites withstood 482.5 m/s ± 5 limit of bullet velocity, satisfying the NIJ test at level II. The findings give a strong sound basis decision to engineers whether or not green composites are qualified to replace synthetic composites in certain engineering applications. | Aidy Ali Rabiatun Adawiyah Kannan Rassiah Wei Kuan Ng Faiz Arifin Faiz Othman Muhammad Shauqi Hazin M.K. Faidzi M.F. Abdullah M.M.H. Megat Ahmad | 2019 | Defence Technology(防务技术)2019，15，3： | 1 |
| 3 | Non-Destructive Techniques (NDT) in Composite Materials显示文摘 | Suriani M.J. Ali Aidy Sapuan S.M. Khalina Abdan | 2011 | Key Engineering Materials2011，，462： | 1 |
| 4 | Develop- ment of anti ballistic board from ramie fiber显示文摘 | ALI Aidy SHAKER Z R KHALINA A | 2011 | Polymer- Plastics Technology and Engineering2011，50，62： | 1 |
| 5 | Influence of microstructures on fatigue damage mechanisms in Ti15-3 alloy显示文摘 | Z N Ismarrubie Aidy Ali T Satake | | 0，，03： | 1 |
| 6 | Modelling of crack coalescence in 2024-T351 Al alloy friction stir welded joints显示文摘 | Aidy Ali Brown M W Rodopoulos C A | 2008 | International Journal of Fatigue2008，30，： | 1 |
| 7 | Modelling of crack coalescence in 2024-7351 Al alloy friction stir welded joints显示文摘 | ALI Aidy BROWN M W RODOPOULOS C A | 2008 | International Journal of Fatigue2008，30，： | 1 |
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