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| 1 | Serum levels of vaspin and visfatin in patients with coronary artery disease—Kozani study显示文摘 | Nikolaos P.E. Kadoglou Argirios Gkontopoulos Alkistis Kapelouzou Grigorios Fotiadis Efstratios K. Theofilogiannakos George Kottas Stilianos Lampropoulos | 2010 | Clinica Chimica Acta2010，，1： | 3 |
| 2 | Associations between serum relaxin 2, aneurysm formation/size and severity of atherosclerosis: a preliminary prospective analysis显示文摘(RL2 ) 浆液松弛激素 2 是对各种各样的机关和系统起作用的多种的荷尔蒙,特别地心血管的系统。尽管 RL2 似乎是氮的一氧化物的合成到 upregulate (没有) 并且它在动脉粥样硬化和动脉瘤形成的角色上的矩阵 metalloproteinase (MMP )-2 和 -9, 水流文学是少见的。这研究的目的是与一个动脉的动脉瘤以及在动脉粥样硬化患者病人在病人调查浆液 RL2 的层次,并且相关他们与他们的相关脉管的疾病的严厉。53 个题目的一个总数在这研究被注册:37 个病人被安排经历外科:为动脉粥样硬化患者疾病(ATH ) 的不同形式的 21 个病人,为一个动脉的动脉瘤(AA ) 的 16 个病人,为经历时间的动脉活体检视(标签) 的 6 个病人,和 10 个健康献血者(HBD ) 担任了控制组。RL2 用 enzymelinked immunosorbent 试金被测量。RL2 在与 ATH 相比的 AA 病人是显著地更高的(P < 0.01 ) ,标签(P < 0.001 ) 并且 HBD (P < 0.01 ) 。没有重要差别在 ATH 和标签组之间被发现(P > 0.05 ) 。另外, ATH 和 AA 病人进一步基于他们的疾病的严厉被细分。浆液 RL2 日益增多地与动脉的动脉瘤在病人被增加,显示出与 aneurysmatic 膨胀的尺寸的一种积极关系。由对比, RL2 水平是相反地与动脉粥样硬化患者疾病的严厉有关。有合并一张一致学习人口的一个更大的队的研究被保证验证我们的结果并且使这些过程的机械学的背景清楚些。 | Konstantinos PAPOUTSIS Alkistis KAPELOUZOU Diamantis I TSILIMIGRAS Nikolaos PATELIS Georgios KOUVELOS Dimitrios SCHIZAS Ioannis KARAVOKYROS Sotirios GEORGOPOULOS | 2018 | Acta Pharmacologica Sinica2018，39，7： | 2 |
| 3 | Tissue-specific relaxin-2 is differentially associated with the presence/size of an arterial aneurysm and the severity of atherosclerotic disease in humans显示文摘Circulating or tissue-related biomarkers are of clinical value for risk stratification in patients with abdominal aortic aneurysms.Relaxin-2(RL2)has been linked to the presence and size of arterial aneurysms,and to the extent of atherosclerosis in human subjects.Here,we assessed the expression levels of RL2 in aneurysmal(AA,n=16)and atherosclerotic(ATH,n=22)arteries,and established the correlation between RL2 levels and the presence/size of AA and the clinical severity of atherosclerosis.The expression levels of metalloproteinases(MMPs)and endothelial nitric oxide synthetase(eNOS)were also detected for correlations with different phenotypes of atherosclerosis and AA.Temporal artery biopsy specimens(n=6)and abdominal aortic tissues harvested from accident victims during autopsy(n=10)were used as controls.Quantitative tissue biomarker analysis revealed that tissue-specific RL2 was increased in patients with larger or symptomatic AA compared to subjects with atherosclerotic disease and healthy controls.In situ RL2 levels were proportional to the size and the severity of aneurysmatic disease,and were substantially elevated in patients with symptomatic aneurysm of any diameter or asymptomatic aneurysm of a diameter>350%of that of the normal artery.In contrast,tissue RL2 was inversely associated with the clinical severity of atherosclerotic lesions.Correlation between RL2 and MMP2 was different between ATH1 and ATH2,depending on atherosclerosis grade.Overall,tissue RL2 is differentially associated with discrete phenotypes of arterial disease and might exert multipotent biological effects on vascular wall integrity and remodeling in human subjects. | Konstantinos Papoutsis Alkistis Kapelouzou Georgios Georgiopoulos Christos Kontogiannis Christos Kourek Konstantinos S Mylonas Nikolaos Patelis Dennis V Cokkinos Ioannis Karavokyros Sotirios Georgopoulos | 2020 | Acta Pharmacologica Sinica2020，41，6： | 1 |
| 4 | Effects of atorvastatin on apelin, visfatin (nampt), ghrelin and early carotid atherosclerosis in patients with type 2 diabetes显示文摘 | Nikolaos Kadoglou Nikolaos Sailer Alkistis Kapelouzou Stylianos Lampropoulos Ioulia Vitta Alkiviadis Kostakis Christos Liapis | 2012 | Acta Diabetologica2012，，4： | 1 |
| 5 | The association of physical activity with novel adipokines in patients with type 2 diabetes 显示文摘 | NIKOLAOS P E KADOGLOU IOANNIS S VRABAS ALKISTIS KAPELOUZOU | 2012 | EurJ Int Med2012，23，： | 1 |
| 6 | Serum levels of apelin and ghrelin in patients with acute coronary syndromes and established coronary artery disease—KOZANI STUDY显示文摘 | Nikolaos P.E. Kadoglou Stilianos Lampropoulos Alkistis Kapelouzou Argirios Gkontopoulos Efstratios K. Theofilogiannakos Grigorios Fotiadis George Kottas | 2010 | Translational Research2010，，5： | 1 |
| 7 | Erythrocyte membrane cholesterol and lipid core growth in a rabbit model of atherosclerosis: Modulatory effects of rosuvastatin显示文摘 | Dimitrios Tziakas Georgios Chalikias Alkistis Kapelouzou Ioannis Tentes Katrin Sch?fer Panagiotis Karayannakos Alkiviadis Kostakis Harissios Boudoulas Stavros Konstantinides | 2013 | International Journal of Cardiology2013，，2： | 1 |
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