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| 1 | 腹腔镜治疗多囊卵巢综合征显示文摘 | Saad A K Amer TC Li 杨硕(翻译) 马彩虹(审校) | 2010 | 中国微创外科杂志2010,10,3: | 6 |
| 2 | Ghrelin attenuates gastrointestinal epithelial damage induced by doxorubicin显示文摘AIM:To examine the influence of ghrelin on the regenerative potential of gastrointestinal(GI)epithelium.METHODS:Damage to GI epithelium was induced in mice by two intravenous injections of doxorubicin(10 and 6 mg/kg).Some of the doxorubicin-treated mice received a continuous subcutaneous infusion of ghrelin(1.25μg/h)for 10 d via implanted mini-osmotic pumps.To label dividing stem cells in the S-phase of the cell cycle,all mice received a single intraperitoneal injection of 5'-bromo-2'-deoxyuridine(BrdU)one hour before sacrifice.The stomach along with the duodenum were then removed and processed for histological examination and immunohistochemistry using anti-BrdU antibody.RESULTS:The results showed dramatic damage to the GI epithelium 3 d after administration of chemotherapy which began to recover by day 10.In ghrelintreated mice,attenuation of GI mucosal damage was evident in the tissues examined postchemotherapy.Immunohistochemical analysis showed an increase in the number of BrdUlabeled cells and an alteration in their distribution along the epithelial lining in response to damage by doxorubicin.In mice treated with both doxorubicin and ghrelin,the number of BrdUlabeled cells was reduced when compared with mice treated with doxorubicin alone.CONCLUSION:The present study suggests that ghrelin enhances the regenerative potential of the GI epithelium in doxorubicintreated mice,at least in part,by modulating cell proliferation. | Mohamed A Fahim Hazem Kataya Rkia El-Kharrag Dena AM Amer Basel al-Ramadi Sherif M Karam | 2011 | World Journal of Gastroenterology2011,17,33: | 3 |
| 3 | Treatment of hepatitis C virus genotype 4 with peginterferon alfa-2a: Impact of bilharziasis and fibrosis stage显示文摘AIM: To evaluate pegylated interferon alpha2a (PegIFN- α2a) in Egyptian patients with HCV genotype 4, and the impact of pretreatment viral load, co-existent bilharziasis and histological liver changes on response rate. METHODS: A total of 73 na?ve patients (61 with history of bilharziasis) with compensated chronic HCV genotype 4 were enrolled into: group A (38 patients) who received 180 mg PegIFN-alpha2a subcutaneously once weekly for a year and group B (35 patients) received IFN alpha-2a 3 MU 3 times weekly. Ribavirin was added to each regimen at a dose of 1200 mg. Patients were followed for 72 wk and sustained response was assessed. RESULTS: Significant improvement in both end of treatment response (ETR) (P < 0.002) and sustained response (SR) (P < 0.05) was noted with pegylated interferon, where ETR was achieved in 29 (76.3%) and 14 patients (40%) in both groups respectively, and 25 patients in group A (65.8%) and 9 (25.7%) in group B could retain negative viraemia by the end of follow up period. Sustained virological response (SVR) showed a significant negative correlation with age and positive correlation with pretreatment inflammation in patients receiving PegIFN. Viral clearance after 3 mo of therapy was associated with high incidence of ETR and SR (P < 0.001), but without significant difference between both forms of interferon. Significant improvement in response was achieved in patients with high grade fibrosis (grade 3 and 4) with PegIFN-α2a, where SR was seen in 5 out of 13 patients in group A, but none in group B. There was no significant difference in response betweenbilharzial and non-bilharzial patients in both groups. In terms of safety and tolerability, neutropenia was the predominant side effect; both drugs were comparable. CONCLUSION: PegIFN-α2a combined with ribavirin results in improvement in sustained response in HCV genotype 4, irrespective of history of bilharzial infestation. | MF Derbala SR Al Kaabi NZ El Dweik F Pasic MT Butt R Yakoob A Al-Marri AM Amer N Morad A Bener | 2006 | World Journal of Gastroenterology2006,12,35: | 3 |
| 4 | Biomechanical Evaluation of Nano-Zirconia Coatings on Ti-6Al-7Nb Implant Screws in Rabbit Tibias显示文摘 | Thekra I. Hamad Abdalbseet A Fatalla Amer Subhi Waheed Zena G. M. Azzawi Ying-guang CAO Ke SONG | 2018 | Current Medical Science2018,38,3: | 2 |
| 5 | The feasibility of integrating ME-TVC+MEE with azzour south power plant:Economic evaluation显示文摘 | F N Alasfour A O Bin Amer | 2006 | Desalination2006,,197: | 1 |
| 6 | Investigation of the direct hydrometallurgical processing of mechanically activated low-grade wolizamite concentrate 显示文摘 | Amer A M | 2000 | HydrometaUurgy2000,58,3: | 1 |
| 7 | Human adipose triglyceride lipase(PNPLA2)is not regulated by obesity and exhibits low in itro triglyceride hydrolase activity显示文摘 | Mairal A Langin D Amer P | | 0,,7: | 1 |
| 8 | Influence of Al2O3 nano-dispersionson microstructure features and mechanical properties of cast and T6 heat-treated Al-Si hypoeutectic Alloys显示文摘 | I El-Mahallawi H Abdelkader L Yousef A Amer J Mayer A Schwedt | 2012 | Materials Science&Engineering A2012,556,: | 1 |
| 9 | Oil spill sorption using carb- onized pith bagasse: trial for practical application显示文摘 | Hussein M Amer A A Sawsan lI | 2008 | International Journal of Environmental Science &Technology2008,5,2: | 1 |
| 10 | Assessment of inorganic lead specie and total organo-alkyl lead in some Egyptian agricultural soils显示文摘 | ELSOKKARY H I AMER A M SHALABY E A | 1995 | Environmental Pollution1995,,87: | 1 |
| 11 | Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in re-sponse to viral infection and double-stranded RNA 显示文摘 | KANNEGANTIT D BODY-MALAPEL M AMER A | 2006 | J BiolChem2006,281,36: | 1 |
| 12 | Vitamin D receptor genotypes in osteoporosis显示文摘 | Kindmar A Amer S | 1994 | Lancet1994,344,: | 1 |
| 13 | FGF21 attenuates lipolysis in human adipocytes-A possible link to improved insulin sensitivity显示文摘 | Amer P Pettersson A Mitchell P J | 2008 | FEBS Lett2008,582,: | 1 |
| 14 | Oil spill sorption using carbonized pith bagasse: Application of carbonized pith bagasse as loose fiber 显示文摘 | HUSSEIN M AMER A A SAWSAN I I | 2009 | Global NEST Journal2009,11,4: | 1 |
| 15 | Lung infections and innate host defense 显示文摘 | Valdivia-Arenas MA Amer A Henning LN | 2007 | Drug Discov Today Dis Mech2007,4,2: | 1 |
| 16 | Prospective comparative study between microsurgical and conventional testicular sperm extraction in non-obstructive azoospermia:follow-up by serial ultrasound examinations显示文摘 | Amer M Ateyah A Hany R | 2000 | Hum Reprod2000,15,: | 1 |
| 17 | Femto- second versus nanosecond laser micmmachining: comparison of induced stresses and structural changes in silicon wafers显示文摘 | AMER M S EL- ASHRY M A DOSSER L R | 2005 | Ap- plied Surface Science2005,242,: | 1 |
| 18 | Availability of barley straw application on oil spill clean up 显示文摘 | HUSSEIEN M AMER A A EL-MAGHRABY A TAHA N A | 2009 | International Journal of Environmental Science and Technology2009,6,1: | 1 |
| 19 | The association between age and nephrosclerosis on renal biopsy among healthy adults显示文摘 | Rule A D Amer H Cornell L D | 2010 | Ann Intern Med2010,152,9: | 1 |
| 20 | cadmium biosorption by a cadmium resistant strain of Bacillus thuringiensis:regulation and op- timization of cell surface affinity for metal cations 显示文摘 | E1 - Helow E R Sabry S A Amer R M | 2000 | Biometals2000,13,4: | 1 |