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| 1 | 高效液相色谱-紫外检测法同时测定药物制剂及人体血清中的奥美沙坦酯和厄贝沙坦及氢氯噻嗪(英文)显示文摘A simple,selective,sensitive,precise,simultaneous high performance liquid chromatographic analysis of serum samples and commercial tablet formulation containing hydrochlorothiazide,olmesartan medoxomil and irbesartan are reported.Good chromatographic separation was achieved using a μ-Bondapak,C18 column(15 cm×4.6 mm,5 μm),and a mobile phase consisting of acetonitrile-0.2% acetic acid aqueous solution(50∶50,v/v)at a flow rate of 1.0 mL/min.The ultraviolet detector was set at a wavelength of 260 nm.Hydrochlorothiazide,olmesartan medoxomil,and irbesartan were eluted at 1.2,3.8,and 4.4 min,respectively.No extraneous materials were found to interfere.The method uses protein precipitation with acetonitrile for the preparation of serum sample.The linear ranges for hydrochlorothiazide,olmesartan medoxomil,and irbesartan were 6.25-18.75,20-60,and 75-225 ng/mL,respectively.The recoveries of hydrochlorothiazide,olmesartan medoxomil,and irbesartan in spiked samples were all greater than 98%,and their relative standard deviations were less than 2.0%.The limits of detection were 1,2,and 2 ng/mL for hydrochlorothiazide,olmesartan medoxomil,and irbesartan,respectively,and the limits of quantification were 3 ng/mL,which allow their determination at the expected serum concentration levels. | SULTANA Najma ARAYNE M Saeed ALI S Shahid SAJID Shahnawaz | 2008 | 色谱2008,26,5: | 6 |
| 2 | Synthesis and antibacterial studies of ciprofloxacin-metal complexes显示文摘Metal complexes of ciprofloxacin were synthesized to study the effect of the drug on the metals present in the body or metals co-administered as multivitamin therapy. These complexes were then characterized by IR, UV, 1 H NMR, CHN and AA analyses. It was found that the metals coordinated through the β-keto carboxylic group, forming four coordinated complexes having square planar geometry. The effect of the antibacterial activity of these complexes with respect to parent drug was also studied against 14 different Gram + ve and Gram – ve organisms by the disk susceptibility technique. Some complexes showed improve activity as compared with the stated drug. | Najma Sultana M.Saeed Arayne Ahsan Zamir Siddiqi Agha Zeeshan Mirza | 2019 | Journal of Chinese Pharmaceutical Sciences2019,28,6: | 2 |
| 3 | Fabrication of nanoparticles within polymeric pores for controlled release of drug 显示文摘 | Asif M Arayne MS Sultana N | 2006 | Pak J Pharm Sci2006,19,1: | 1 |
| 4 | Fabrication of nanoparticles within polymeric pores for controlled release of drug显示文摘 | ASIF M ARAYNE M S SULTANA N | 2006 | Pak J Pharm Sci2006,19,1: | 1 |
| 5 | Grape fruit juice-drug interactions显示文摘 | Sultana N Bibi Z | 2005 | Pak J Pharm Sci2005,18,4: | 1 |
| 6 | Fabrication of nanoparticles within polymeric pores for controlled release of drug 显示文摘 | Asif M Arayne MS Sultana N | 2006 | Pak J Pharm Sci2006,19,1: | 1 |
| 7 | Fabrication Dfnanoparticles within polymeric pores for controlled release of drug显示文摘 | Asif M Arayne MS Sultana N | 2006 | Pak J Pharm Sci2006,19,1: | 1 |
| 8 | Simultaneous determination of metformin, cimetidine, famotidine, and ranitidine in human serum and dosage formulations using HPLC with UV detection显示文摘 | Arayne MS Sultana N Zuberi MH | 2010 | J Chromatogr Sci2010,48,9: | 1 |
| 9 | Synthesis and characterization of gliclazide complexes of magnesium, calcium, chromium, manganese, iron, nickel, copper, zinc and cadmium salts显示文摘 | ARAYNE M S SULTANA N ZAMAN M K | 2005 | Journal of Pharmaceutical Sciences2005,18,4: | 1 |
| 10 | Development and validation of new assay method for the simultaneous analysis of diltiazem,metformin,piog-litazone and rosiglitazone by RP-HPLC and its applications in pharmaceuticals and human serum显示文摘 | Sultana N Arayne MS Shafi N | 2011 | J Chromatogr Sci2011,49,10: | 1 |
| 11 | Simultaneous determination of cefazolin or ceftizoxime in presence of ascorbic acid from pharmaceutical formulation and human serum by RP-HPLC显示文摘 | Arayne M S Sultana N Bi Bi Z | 2007 | Pak J Pharm Sci2007,20,1: | 1 |
| 12 | Sparfloxacin metal complexes as antifungal agents-Their synthesis,characterization and antimicro-bial activities显示文摘 | Najma Sultana Saeed Arayne Somia Gul | | 0,,06: | 1 |
| 13 | A new RP-HPLC method for analysis of meloxicam in tablets显示文摘 | Arayne M S Sultana N Siddiqui F A | | 0,,01: | 1 |
| 14 | Validated Method for the Simultaneous Determination of Lisinopril, Pravastatin, Atorvastatin and Rosuvastatin in API, Formulations and Human Serum by RP-HPLC显示文摘Lisinopril 被发现作为降低药的胆固醇在高血压和 statins 有用。现在的工作在 pravastatin, atorvastatin,和 rosuvastatin 使用 RP-HPLC 方法的存在为 lisinopril 的同时的决心被设计。Purospher 星 C18 (5 m, 25 慥r ?? ? | Najma, Sultana Arayne, M. Saeed Safila, Naveed | 2011 | Chinese Journal of Chemistry2011,29,6: | 1 |
| 15 | Simultaneous determination of gliquidone,pioglitazone hydrochloride,and verapamil in formulation and human serum by RP-HPLC显示文摘 | ARAYNE MS SULTANA N MIRZA AZ | 2011 | J Chromatogr Sci2011,49,2: | 1 |
| 16 | The berberis story: Berberis vulgaris in therapeutics显示文摘 | Arayne MS Sultana N Bahadur SS | 2007 | Pak J Pharm Sci2007,20,1: | 1 |
| 17 | Interactions between sparfloxacin and antacids-dissolution and adsorption studies显示文摘 | HUSSAIN F ARAYNE M S SULTANA N | | 0,,01: | 1 |
| 18 | Interactions between sparfloxacin and antacids-dissolution and adsorption stud- ies 显示文摘 | Hussain F Arayne M S Sultana N | 2006 | Pakistan Journal of Pharmaceutical Sciences2006,19,1: | 1 |
| 19 | Spectrophotometric determination of gabapentin in pharmaceutical formulations using ninhydrin and &-aeceptors 显示文摘 | SIDDIQUI F A ARAYNE M S SULTANA N | 2010 | European Journal of Medicinal Chemistry2010,45,7: | 1 |
| 20 | In vitro aetivity of cefadroxil, eephalexin, ccfatrizine and eefpirome ill presence of essential and trace elcments显示文摘 | Najma S Arayne M S | 2007 | Pakistan Journal ot Pharmarmaceutical Sciences2007,20,4: | 1 |