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1Helicobacter pylori infection as a cause of iron deficiency anaemia of unknown origin显示文摘AIM: To assess the aetiological role of Helicobacter pylori (H. pylori) infection in adult patients with ironrefractory or iron-dependent anaemia of previously unknown origin. METHODS: Consecutive patients with chronic irondeficient anaemia (IDA) with H. pylori infection and a negative standard work-up were prospectively evaluated. All of them had either iron refractoriness or iron dependency. Response to H. pylori eradication was assessed at 6 and 12 mo from follow-up. H. pylori infection was considered to be the cause of the anaemia when a complete anaemia resolution without iron supplements was observed after eradication. RESULTS: H. pylori was eradicated in 88 of the 89 patients. In the non-eradicated patient the four eradicating regimens failed. There were violations of protocol in 4 patients, for whom it was not possible to ascertain the cause of the anaemia. Thus, 84 H. pylori eradicated patients (10 men; 74 women) were available to assess the effect of eradication on IDA. H. pylori infection was considered to be the aetiology of IDA in 32 patients (38.1%; 95%CI: 28.4%-48.8%). This was more frequent in men/postmenopausal women than in premenopausal women (75% vs 23.3%; P < 0.0001) with an OR of 9.8 (95%CI: 3.3-29.6). In these patients, anaemia resolution occurred in the first follow-up visit at 6 mo, and no anaemia or iron deficiency relapse was observed after a mean follow-up of 21 ± 2 mo. CONCLUSION: Gastric H. pylori infection is a frequent cause of iron-refractory or iron-dependent anaemia of previously unknown origin in adult patients.Helena Monzón Montserrat Forné Maria Esteve Mercé Rosinach Carme Loras Jorge C Espinós Josep M Viver Antonio Salas Fernando Fernández-Baares 2013World Journal of Gastroenterology2013,19,26:13
2螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 2018中华高血压杂志2018,26,3:7
3地中海膳食干预研究中来自胆碱通路的血浆代谢物与心血管病风险的关系显示文摘血浆甜菜碱水平以及胆碱代谢水平与主要心血管病终点之间的联系仍不清楚。研究者评估了胆碱通路的代谢物与偶发心血管病风险以及地中海膳食干预的潜在调节效应之间的相关性。黄洁 叶鹏 Guasch-Ferré M Hu FB Ruiz-Canela M Bulló M Toledo E Wang DD Corella D Gómez-Gracia E Fiol M Estruch R Lapetra J Fitó M Arós F Serra-Majem L Ros E Dennis C Liang L Clish CB Martínez-González MA Salas-Salvadó J 2017中华高血压杂志2017,25,12:2
4由磁共振成像评估的主动脉弓脉搏波传导速度是心血管事件的预测因子:多种族动脉粥样硬化研究显示文摘通过磁共振成像评估的主动脉弓脉搏波传导速度(pulse wave velocity,PWV)对心血管病事件的预测价值尚未完全确定。为了评估多种族动脉粥样硬化研究(multi-ethnic study of atherosclerosis,MESA)受试者中主动脉弓PWV与心血管病的关系,Ohyama等纳入3527例MESA受试者[基线时平均年龄为(62±10)岁,47%为男性],刘莉 叶鹏 Ohyama Y Ambale-Venkatesh B Noda C Kim JY Tanami Y Teixido-Tura G Chugh AR Redheuil A Liu CY Wu CO Hundley WG Bluemke DA Guallar E Lima JAC 2017中华高血压杂志2017,25,8:2
5The role of ultrasonography and automatic-needle biopsy in outpatient percutaneous liver biopsy显示文摘KD Lindor C Bru RA Jorgensen J Rakela JM Bordas JB Gross J Rodes DB McGill CC Reading EM James JW Charboneau J Ludwig KP Batts AR Zinsmeister 1996Hepatology1996,,5:2
6Diagnostic dilemma of sudden deaths due to acute hemorrhagic pancreatitis显示文摘Tümer AR Dener C 2007J Forensic Sci2007,52,1:1
7A strong inverse relationship between PAI-1 and LP (a) in hypertensive type 2 diabetic patients显示文摘 Bontigli AR Sirolla C 1999Diabete Natr Metab1999,12,:1
8A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M显示文摘Meetei AR Medhurst AL Ling C 2005Nat Genet2005,37,9:1
9Experience with testis sparing surgery for testicular teratoma显示文摘Shukla AR Woodard C Carr MC 2004J Urol2004,171,1:1
10Fetal and placental size and risk of hypertension in edult life显示文摘Barker DJ Bull AR Osmond C 1990BMJ1990,301,6746:1
11Relationship among amioda- rone, new class III antiarrhythmics, miscellaneous agents and acquired long QT syndrome显示文摘Riera AR Uchida AH Ferreira C 2008Cardiol J2008,15,3:1
12Surgical and visual outcomes of the type I Boston Kera- toprosthesis for the management of aniridic fibrosis syndrome in congenital aniridia 显示文摘Bakhtiari P Chan C Welder JD de la Cruz J Holland E J Djalil- ian AR 2012Am J Ophthalmol2012,153,5:1
13A soy protein diet alters hepatic lipid metabolism gene expression and reduces serum lipids and re- nal fibrogenic cytokines in rats with chronic nephrotic syndrome 显示文摘Tovar AR Murguia F Cruz C 2002J Nutr2002,132,9:1
14Viscosupplementationin lumbar facet joint arthropathy:a pilot study显示文摘Cleary M Keating C Poynton AR 2008JSpinal Disord Tech2008,21,1:1
15Improved pa-tient/technique survival and peritonitis rates in pa-tients treated with automated peritoneal dialysis whencompared to continuous ambulatory peritoneal dialysisin a Mexican PD center 显示文摘Sanchez AR Madonia C Rascon-Pacheco RA 2008Kidney Int2008,73,:1
16Students' personal traits,violence exposure,family factors,school dynamics and the perpetration of violence inTaiwanese elementary schools显示文摘JIKANG C AVI AR 2011Health Edu Res2011,26,1:1
17Redefinition of Aureoba- sidium puIlulans and its varieties显示文摘ZALAR P GOSTIN AR C IDE HooG Gs 2008Studies in Mycology2008,61,1:1
18Effectiveness and safety of spot scanning proton radiation therapy for chordomas and chon- drosarcomas of the skull base: first long-term report显示文摘Ares C EB Hug AJ Lomax 2009Int J Radiat Oncol Biol Phys2009,75,4:1
19Expression analysis of the long non-coding RNA antisense to Uchl1(AS Uchl1)during dopaminergic cells’differentiation in vitro and in neurochemical models of Parkinson’s disease显示文摘Carrieri C Forrest AR Santoro C 2015Front Cell Neurosci2015,9,:1
20Serum uric acid and risk of coronary heart disease: atherosclerosis risk in communities (ARIC) study显示文摘Morlarity JT Folsom AR Irivarren C 2000Ann Epidemiol2000,10,:1
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