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| 1 | Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy显示文摘AIM: To evaluate the potential association of xeroderma pigmentosum group D (XPD) codon 751 variant with outcome after chemo-radiotherapy in patients with resected gastric cancer. METHODS: We used PCR-RFLP to evaluate the genetic XPD Lys751Gln polymorphisms in 44 patients with stage Ⅲ (48%) and Ⅳ (20%) gastric cancer treated with surgery following radiation therapy plus 5-fluorouracil/ leucovorin based chemotherapy. RESULTS: Statistical analysis showed that 75% (12 of 16) of relapse patients showed Lys/Lys genotype more frequently (P = 0.042). The Lys polymorphism was an independent predictor of high-risk relapse-free survival from Cox analysis (HR: 3.07, 95% CI: 1.07-8.78, P = 0.036) and Kaplan-Meir test (P = 0.027, log-rank test). CONCLUSION: XPD Lys751Gln polymorphism may be an important marker in the prediction of clinical outcome to chemo-radiotherapy in resected gastric cancer patients. | RN Zárate R F Arias E Bandres E Cubedo R Malumbres J García-Foncillas | 2006 | World Journal of Gastroenterology2006，12，37： | 7 |
| 2 | Perfluorocarbon in vitreoretinal surgery and preoperative bevacizumab in diabetic tractional retinal detachment显示文摘AIM: To describe the en bloc perfluorodissection(EBPD) technique and to demonstrate the applicabilityof using preoperative intravitreal bevacizumab duringsmall-gauge vitreoretinal surgery(23-gauge transconjunctival sutureless vitrectomy) in eyes with advancedproliferative diabetic retinopathy(PDR) with tractionalretinal detachment(TRD).METHODS: This is a prospective, interventional caseseries. Participants included 114(eyes) with advancedproliferative diabetic retinopathy and TRD. EBPD wasperformed in 114 eyes(consecutive patients) during23-gauge vitrectomy with the utilization of preoperativebevacizumab(1.25 mg/-0.05 mL). Patients mean age was 45 years(range, 21-85 years). Surgical time had a mean of 55 min(Range, 25-85 min). Mean follow up of this group of patients was 24 mo(range, 12-32 mo). Main outcome measures included best-corrected visual acuity(BCVA), retinal reattachment, and complications.RESULTS: Anatomic success occurred in 100%(114/-114) of eyes. Significant visual improvement [≥ 2 Early Treatment Diabetic Retinopathy Study(ETDRS) lines] was obtained in 69.2%(79/-114), in 26 eyes(22.8%) BCVA remained stable, and in 8 eyes(7%) BCVA decreased(≥ 2 ETDRS lines). Final BCVA was 20/-50 or better in 24% of eyes, between 20/-60 and 20/-400 in 46% of eyes, and worse than 20/-400 in 30% of eyes. Complications included cataract in 32(28%) eyes, iatrogenic retinal breaks in 9(7.8%) eyes, vitreous hemorrhage requiring another procedure in 7(6.1%) eyes, and phthisis bulbi in 1(0.9%) eye.CONCLUSION: This study demonstrates the usefulne-ss of using preoperative intravitreal bevacizumab and EBPD during smallgauge vitreoretinal surgery in eyes with TRD in PDR. | J Fernando Arevalo Martin A Serrano Juan D Arias | 2014 | World Journal of Diabetes2014，5，5： | 3 |
| 3 | Transconjunctival sutureless vitrectomy withtissue plasminogen activator,gas and intravitreal bevacizumabin the management of predominantly hemorrhagic age-relatedmacular degeneration显示文摘 | Arias L Mones J | 2010 | Clin Ophthalmol2010，18，4： | 1 |
| 4 | Effects of feeding corn modified wet distillers grain plus soluble co-ensiled with chopped whole plant corn on heifer growth performance and diet digestibility in beef cattle显示文摘 | ARIAS R P UNRUH-SNYDER L J SCHOLLIEGERDES E J | 2013 | J Anim Sci2013，91，9： | 1 |
| 5 | AVATAR: an improved solution for personalized TV based on semantic inference 显示文摘 | Fernandez Y B Pazos Arias J J Nores M L | 2006 | Consumer Electronics IEEE Transactions on2006，52，1： | 1 |
| 6 | New development in ultimate pit limit problem solution method 显示文摘 | Yegulalp T M Arias A J Muduli P | 1993 | Transactions1993，294，： | 1 |
| 7 | Emissivity of terrestrial materials in the 8- 14 μm atmospheric window 显示文摘 | Salisbury J W D'Aria D M | 1992 | Remote Sensing Environ1992，，42： | 1 |
| 8 | Malguki: An RSSI based Ad Hoc location algorithm显示文摘 | ARIAS J ZULOAGA A LAZARO J | 2004 | Micro Processors and Micro Systems2004，28，8： | 1 |
| 9 | Browning preventionby ascorbic acid and 4-hexylresorcinol : Different mechanisms ofaction on polyphenol oxidase in the presence and in the absenceof substrates显示文摘 | Arias E Gonzalez J Peiro J M | 2007 | Journal of Food Science2007，2，9： | 1 |
| 10 | Noncoherent intense pulsed light for treament of relapsing hairy intrademat melanocytic nevus after shaving exeision显示文摘 | Moreno Arias GA Ferrando J | 2001 | Laser Surg Med2001，29，： | 1 |
| 11 | Calibration of LAI2000 to estimate leaf area index(LAI) and assessment of its relationship with stand productivity in six native and introduced tree species in Costa Rica显示文摘 | Arias D Calvo-Alvarado J Dohrenbusch A | 2007 | Forest Ecology and Management2007，247，： | 1 |
| 12 | Hydrogenolysis of glycerol to propanediols over a Pt/ASA catalyst: The role of acid and metal sites on product selectivity and the reaction mechanism 显示文摘 | Gandarias I Arias P L Requies J | 2010 | Applied Catalysis B: Environmental2010，97，1： | 1 |
| 13 | Cytokine levels ( IL - 6 and IFN - γ) acute phase response and nu- tritional status as prognostic actors in lung cancer 显示文摘 | Antonio M ilena Em ilio Gonzlez -Reimers M aria J Brito | 1999 | Cytokine1999，11，1： | 1 |
| 14 | Assymetric Eigenvalue Problems with Weights显示文摘 | ARIAS M CAMPOS J CUESTA M | 2001 | CRAST2001，332，1： | 1 |
| 15 | IntervertebraI disc degeneration in relation to the COL9A3 and the IL-1B gene polymorphisms显示文摘 | Solovieva S Lohiniva J Leino Arias P Raininko R Luoma K Ala Kokko L | 2006 | EurSpine J2006，15，： | 1 |
| 16 | Influence of conical projectile diameter on perpendicular impact of thin steel plate 显示文摘 | Rusinek A Rodrlguez-Martinez J A Arias A | 2008 | Engineering Fracture Mechanics2008，75，： | 1 |
| 17 | Effects of iron and organic matter on the porosity and structural stability of soil aggregate 显示文摘 | Barral M T Arias M Guerif J | 1998 | Soil & Tillage Res1998，46，： | 1 |
| 18 | Effeet of free range feeding on n-3 fatty adic and a-toeopherol content and oxidative stability of eggs 显示文摘 | LoPez-Botc C J Sanz Arias R Rey A I | 1998 | Animal Feed sci Tech1998，72，10： | 1 |
| 19 | Diagnosis and management of benign paroxysmal positional vertigo(BPPV)显示文摘 | Parries LS Agrawal SK Arias J | 2003 | CMAJ2003，169，7： | 1 |
| 20 | Effects of plough pan development on surface hydrology and on soil physical properties in Southeastern Brazilian pla- teau显示文摘 | Bertolino Aria V F A Fernandes N F Miranda J P L | 2010 | J Hydro2010，393，12： | 1 |
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