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| 1 | 1995—2014年7个高收入国家癌症生存率、死亡率和发病率进展:一项以人群为基础的研究显示文摘以人群为基础的癌症生存率可以有效评估癌症防治服务的效果。本研究从7个国家抽取21个肿瘤登记处390万例癌症资料,包括1995—2014年诊断的食道、胃、结肠、宜肠、胰腺、肺和卵巢7类癌症病例,及其截至2015年12月31日的生存状态随访数据。 | Arnold M Rutherford MJ Bardot A 李辉章(编译) | 2019 | 中华预防医学杂志2019，53，12： | 33 |
| 2 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 3 | DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection显示文摘 | Oertli Mathias Sundquist Malin Hitzler Iris Engler Daniela B Arnold Isabelle C Reuter Sebastian Maxeiner Joachim Hansson Malin Taube Christian Quiding-J?rbrink Marianne Müller Anne | 2012 | EN2012，，3： | 5 |
| 4 | Mental and physical symptoms associated with lower social support for patients with hepatitis C显示文摘AIM: To systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study. METHODS: Patients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support. RESULTS: A total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. Lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP. CONCLUSION: Patients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting support persons and the stressors identified in our findings may lessen or alleviate the social strains patients with hepatitis C experience. | Julie A Blasiole Laura Shinkunas Douglas R LaBrecque Robert M Arnold Susan L Zickmund | 2006 | World Journal of Gastroenterology2006，12，29： | 5 |
| 5 | Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells显示文摘 | Arnold Isabelle C Dehzad Nina Reuter Sebastian Martin Helen Becher Burkhard Taube Christian Müller Anne | 2011 | Journal of Clinical Investigation2011，，8： | 4 |
| 6 | 低能电子在外层导电屏蔽的玻璃锥管中的传输显示文摘采用新的具有常数锥角的玻璃锥管,并对玻璃锥管进行了外表面导电屏蔽,通过对电子穿越玻璃锥管的二维角分布随时间演化的观测,研究了低能电子与玻璃管相互作用的机制.发现电子穿越完全放电的玻璃锥管时穿透率先下降后平稳,整个过程中角分布中心发生微小移动,但角分布的半高宽几乎保持不变.这与我们之前发表的工作(2016 Acta Phys.Sin.65 204103)不同,这是由于对玻璃锥管进行外表面导电屏蔽会阻止外界不确定的快速充放电的影响,并形成了新的稳定放电通道,有利于实现电子的稳定穿透.电子的穿透率随倾角呈类似矩形的分布,透射电子的角分布中心伴随倾角的变化而移动,其穿透所容许的倾角与几何穿透一致. | 钱立冰 李鹏飞 靳博 靳定坤 宋光银 张琦 魏龙 牛犇 万成亮 周春林 Arnold Milenko Müller Max Dobeli 宋张勇 杨治虎 Reinhold Schuch 张红强 陈熙萌 | 2017 | 物理学报2017，66，12： | 3 |
| 7 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015，5，4： | 3 |
| 8 | Rotational relaxation measurements of laser excited Hydrogen fluoride显示文摘 | Peterson L M Lindgulst G H Arnold C B | 1974 | J Chem Phys1974，61，8： | 2 |
| 9 | Interrelations among protein,lysine oil,certain mineral element concentration,and physic kernel characteristics in two maize populations显示文摘 | Arnold J M | 1977 | Crop Science1977，17，3： | 1 |
| 10 | Contrastenhanced transcranial colour-coded duplex sonography in ischemic cerebrovascular disease显示文摘 | Baumgartner R Arnold M Gonner F | 1997 | Stroke1997，28，： | 1 |
| 11 | Regulation of Toll - like receptor 4 -associated MD - 2 in intestinal epithelial cells: A comprehensive analysis显示文摘 | Vamadevan AS Fukata M Arnold ET | 2010 | Innate Immun2010，16，2： | 1 |
| 12 | Understanding the cus- tomer base of service providers:An examination of the differ- ences and switchers and stayers 显示文摘 | Ganesh J Arnold M J Reynolds K E | 2000 | Journal of Marketing2000，64，3： | 1 |
| 13 | Expression of p53,bcl-2,E-Cadherin,Matrix Metalloproteinase-9,and Tissue Inhibitor of Metalloproteinases-1 in Paired Primary Tumors and Brain Metastasis显示文摘 | Susanne M Arnold A Byron Young | 1999 | Clinical Cancer Research1999，5，10： | 1 |
| 14 | A cell-loss concealment technique for MPEG-2 coded video 显示文摘 | ZHANG J Arnold J F Frater M R | 2000 | IEEE Transactions on Circuits and Systems for Video Technology2000，10，4： | 1 |
| 15 | C - reactive protein andthe 10 - year incidence of coronary heart disease in older men andwomen : the cardiovascular health study 显示文摘 | Cushman M Arnold AM Psaty BM | 2005 | Circulation2005，112，1： | 1 |
| 16 | A Cell-loss Concealment Technique for MPEG-2 Coded Video显示文摘 | Zhang J Arnold J F Frater M R | | 0，，： | 1 |
| 17 | Solid-state digital micro-mirror array spectrometer for Hadamard transform measurements of glucose and lactate in aqueous solutions 显示文摘 | Xiang D Arnold M A | 2011 | Applied Spectroscopy2011，65，10： | 1 |
| 18 | Guidelines for the management of spontaneous pneumothorax显示文摘 | Henry M Arnold T Harvey J | 2008 | Thorax2008，58，11： | 1 |
| 19 | Clinical and radiological predictors of recanalisation and outcome of 40 patients with acute basilar artery occlusion treated with intra-arterial thrombolysis显示文摘 | Arnold M Nedeltchev K Schroth G | | 0，，06： | 1 |
| 20 | EWMA control charts with variable sample sizes and variable sampling intervals显示文摘 | Jr REYNOLDS M R ARNOLD J C | | 0，，06： | 1 |
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