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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | High-aspect 3D two-photon polymerization structuring with widened objective working range (WOW-2PP)显示文摘We developed a novel two-photon polymerization(2PP)configuration for fabrication of high-aspect three-dimensional(3D)structures,with an overall height larger than working distance of the microscope objective used for laser beam focusing into a photosensitive material.This method is based on a modified optical 2PP setup,where a microscope objective(1003 high N.A.),immersion oil and cover glass can be moved together into the photosensitive material,resulting in an effective higher and wider objective working range(WOW-2PP).The proposed technique enables the fabrication of high-aspect structures with sub-micrometer process resolution.3D structures with a height of 7 mm are demonstrated,which could hardly be built with the conventional 2PP set-up due to refractive index mismatch and laser beam disturbances. | Kotaro Obata Ayman El-Tamer Lothar Koch Ulf Hinze Boris N Chichkov | 2013 | Light(Science & Applications)2013，2，1： | 7 |
| 3 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 4 | Combining array processing and space-time coding显示文摘 | VAHID T AYMAN N NAMBI S | 1999 | IEEE Trans on Information Theory1999，45，4： | 1 |
| 5 | Unsaturated polyester resins based on rosin maleic Anhydride adduct as corrosion protec- tions of steel显示文摘 | AYMAN M A IBRAHIM F N HAMED M B | 2007 | Reactive & Functiona Polymers2007，67，7： | 1 |
| 6 | The ketolides-A critical review显示文摘 | Michael W Ayman N | 2002 | Drugs2002，62，12： | 1 |
| 7 | Parallel ant colony optimization显示文摘 | SAMEH A AYMAN A HASAN N | 2010 | International Journal of Research and Reviews in Computer Sci-ence2010，1，2： | 1 |
| 8 | Neural network based method for leakage current prediction of polymeric insulators 显示文摘 | ALl N J AYMAN H H SHESHA H JAYARAM A | 2006 | IEEE Transactions on Power Delivery2006，21，1： | 1 |
| 9 | Analysis of surface permanent magnet machines with fractional s- lot concentrated windings显示文摘 | AYMAN M R THOMAS M J DONALD W N | 2006 | IEEE Transactions on Energy Conversion2006，21，1： | 1 |
| 10 | Array processing and space-time coding 显示文摘 | VAHID T AYMAN N NAMBI S | 1999 | IEEE Transactions on Information Theory1999，45，4： | 1 |
| 11 | Capacity Improvement with Base-Station Antenna Arrays in Cellular CDMA 显示文摘 | AYMAN F N ARORYASWAMI P | 2002 | IEEE Transactions on Vehicular Technology2002，43，3： | 1 |
| 12 | Clinicopathologic and inanu-nohistochemical characteristics of male breast cancer:a single center experience显示文摘 | Ayman N Tawil MD Fouad I | 2012 | Breast2012，18，1： | 1 |
| 13 | Stress-strain model for concrete confined by FRP composites 显示文摘 | MARWAN N YOUSSEF MARIA Q FENG AYMAN S MOSALLAM | 2007 | Composites: Part B Engineering2007，38，56： | 1 |
| 14 | Clinicopathologic and iramu-nohistochemical characteristics of male breast cancer:a single center experience显示文摘 | Ayman N Tawil MD Fouad I | 2012 | Breast J2012，18，1： | 1 |
| 15 | Nw-ni- tro-l-arginine methylester ameliorates myocardial toxicity induced by doxorubicin显示文摘 | Mahmoud AM Ayman GE Mahmoud N | 2003 | J Biochem Mol Bio2003，36，6： | 1 |
| 16 | Decreased serum paraoxonase-1 activity during intestinal nematode (nippostrongylus brasiliensis) infection in rats显示文摘 | AYMAN S F KEIKO N NOBORU M | 2008 | Am J Trop Med Hyg2008，78，： | 1 |
| 17 | Stress- strain model for concrete confined by FRP composites 显示文摘 | MARWAN N Y MARIA Q F AYMAN S M | 2007 | Composites Part B-Engineering2007，38，56： | 1 |
| 18 | Influence of cold weather during casting and curing on the stiffness and strength of concrete显示文摘 | Ayman Y N Michael F P | 2013 | Construction and Building Materials2013，44，： | 1 |
| 19 | 2021亚太心脏病学会P2Y12受体拮抗剂应用于亚太特殊人群的共识显示文摘高龄、糖尿病(DM)和慢性肾脏疾病(CKD)不仅会增加慢性冠状动脉综合征(CCS)患者缺血事件的风险,还会增加其接受抗血小板治疗期间的出血风险。此类特殊人群可能需要调整治疗方案,尤其是亚洲的特殊人群,往往表现出与西方人群不同的临床特征。关于亚洲人群CCS高风险的分类和急性冠状动脉综合征(ACS)后使用新一代强效P2Y12受体抑制剂(如替格瑞洛和普拉格雷)的国际指南已相继发表。本共识总结了在特殊人群中使用强效P2Y12受体抑制剂的相关证据,提出了在冠状动脉疾病(CAD)特殊人群中应用标准疗程双联抗血小板治疗(DAPT)、短期DAPT和单一抗血小板治疗的推荐意见。本共识的特殊人群包括从ACS过渡至CCS,老年,或患有CKD、DM、多血管CAD和治疗期间发生出血并发症等特征的患者。 | Jack Wei Chieh Tan Derek P Chew Kin Lam Tsui Doreen Tan Dmitry Duplyakov Ayman Hammoudeh 张波 李毅 徐凯 Paul J Ong DoniFirman Habib Gamra Wael Almahmeed Jamshed Dalal Lihua Tan Gabriel Steg Quang N Nguyen Junya Ako Jassim Al Suwaidi Mark Chan Mohamed Sobhy Abdulla Shehab Wacin Buddhari 王祖禄 Alan Yean Yip Fong Bilgehan Karadag Byeong-Keuk Kim Usman Baber Chee Tang Chin 韩雅玲 | 2023 | 中华心血管病杂志2023，51，1： | 0 |
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