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| 1 | Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats显示文摘Objective:To evaluate antidiabetic activity of chloroform extracts of Acacia arabica bark, Benincasa hispida fruit,Tinispora cordifolia stem,Ocimum sanctum areal parts and Jatropha curcus leaves.Methods:The chloroform extracts of Acacia arabica bark,Benincasa hispida fruit,Tinospora cordifolia stem,aerial part of Ocimum sanctum and Jatropha curcus leaves were evaluated at different doses(250 and 500 mg/kg body weight.) for antidiabetic potentials in alloxan induced diabetic albino rats.The extracts were administered for two weeks in different groups whereas tolbutamide(80 mg/kg body weight) was used as reference standard throughout study.Results:The result of present study showed test compounds significantly decreases elevated level of serum glucose and also caused to reverse the cholesterol,triglyceride,HDL and LDL values when compared to untreated diabetic rats.Conclusions:Our finding indicates that different test extracts were able to ameliorate the derangements in lipid metabolism caused by diabetes mellitus in alloxan induced diabetic rats towards normal level. | Raju N Patil Ravindra Y Patil Bharati Ahirwar Dheeraj Ahirwar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，1： | 4 |
| 2 | Role of Tumor Necrosis Factor-Alpha (C-863A) Polymorphism in Pathogenesis of Inflammatory Bowel Disease in Northern India显示文摘 | Dinesh Ahirwar Pravin Kesarwani Ranjana Singh Uday Ghoshal Rama Mittal | 2012 | Journal of Gastrointestinal Cancer2012，，2： | 3 |
| 3 | Isolation and characterization of anti-diabetic component(bioactivity-guided fractionation) from Ocimum sanctum L.(Lamiaceae) aerial part显示文摘Objective:To isolate and characterize antidiabetic component(bioactivity-guided fractionation) from hydro alcoholic extract of Ocimum sanctum(O.sanctum) aerial part.Methods:Ten fractions(F1 - F10) were isolated from hydro alcoholic extract of O.sanctum aerial part by column chromatography.All the fractions Fl to F10 were screened for antidiabetic activity in alloxan induced diabetic rats by estimating serum glucose level and lipid parameters.The isolated bioactive component was elucidated on the basis of extensive spectroscopic(UV,IR,MS,1H and 13C NMR) data analysis.Results:The bioactive fraction(F5) was found to be potent antidiabetic by ameliorating glucose and lipid parameters(total cholesterol,triglycerides,low and high density lipoprotein cholesterol).The extensive spectroscopic data analysis reveals that,the isolated bioactive compound elucidated as tetracyclic triterpenoid[16-Hydroxy-4,4,10,13-tetramethyl- 17-(4-methyI-pentyl)-hexadecahydro-cyclopenta[a]phenanthren-3-one].Conclusions:Our present study concluded that,tetracyclic triterpenoid isolated from aerial part of O.sanctum has a great anti-diabetic potential. | Raju Patil Ravindra Patil Bharati Ahirwar Dheeraj Ahirwar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，4： | 2 |
| 4 | Interleukin - 10 G - 1082A and C - 819T polymorphisms as possible molecular markers of urothelial bladder cancer 显示文摘 | Ahirwar D Mandhani A Mittal RD | 2009 | Arch Med Res2009，40，2： | 1 |
| 5 | Role of Tumor Necrosis Factor-Alpha (C-863A) Polymorphism in Pathogenesis of Inflammatory Bowel Disease in Northern India显示文摘 | Dinesh Ahirwar Pravin Kesarwani Ranjana Singh Uday Ghoshal Rama Mittal | 2012 | Journal of Gastrointestinal Cancer2012，，2： | 1 |
| 6 | Evaluation of antifertility activity of Trigonella foenum graeeum seeds 显示文摘 | Ahirwar D Ahirwar B Kharya MD | 2010 | Der Pharm Sci2010，1，3： | 1 |
| 7 | Patient Controlled EPidural Labour Analgesia(PCEA):A Comparison Between Ropivacaine,Ropivacaine-Fentanyl and Ropivacaine-Clonidine显示文摘 | Ahirwar A Prakash R Kushwaha BB | 2014 | J Clin Diagn Res2014，8，8： | 1 |
| 8 | Cytokine gene polymorphisms are associated with risk of urinary bladder cancer and recurrence after BCG immunotherapy显示文摘 | Dinesh K. Ahirwar Anita Agrahari Anil Mandhani Rama D. Mittal | 2009 | Biomarkers2009，，4： | 1 |
| 9 | Impact of nucleotide excision repair ERCC2 and base excision repair APEX1 genes polymorphism and its association with recurrence after adjuvant BCG immunotherapy in bladder cancer patients of North India显示文摘 | GANGAWAR R AHIRWAR D MANDHANI A | 2010 | Med Oncol2010，27，2： | 1 |
| 10 | The efficacy and safety of neoadjuvant chemotherapy in treatment of locallyadvanced carci- noma cervix显示文摘 | Singh U Ahirwar N Rani AK | 2013 | J Obstet Gvnaecol India2013，63，4： | 1 |
| 11 | lnterleukin-10 G-1082A and C-819T polymorphisms as possible molecular markers of urothelial bladder cancer显示文摘 | Ahirwar D Mandhani A Mittal RD | | 0，，02： | 1 |
| 12 | Mobile cloud computing as a future of mobile multimedia database 显示文摘 | Khan A Ahirwar K | 2011 | International Journal of Computer Sci- ence and Communication2011，2，1： | 1 |
| 13 | Thermal aging predictions of polymeric insulation cables from Arrhenius plot using short-term test values显示文摘 | Ramteke P K Ahirwar A K Shrestha N B | | 0，，02： | 1 |
| 14 | RAGE mediatesS100A7-induced breast cancer growth and metastasis bymodulating the tumor microenvironment 显示文摘 | Nasser MW Wani N Ahirwar DK | 2015 | Cancer Res2015，75，6： | 1 |
| 15 | Patient controlled epidural labour analgesia(PCEA):A comparison between ropivacaine,ropivacaine-fentanyl and ropivacaine-clonidine显示文摘 | Ahirwar A Prakash R Kushwaha BB | 2014 | J Clin Diagn Res2014，8，8： | 1 |
| 16 | BCG response prediction with cytokine gene variants and bladder cancer: where we are? 显示文摘 | Ahirwar DK Manchanda PK Mittal RD | 2011 | J Cancer Res Clin Oneol2011，137，12： | 1 |
| 17 | The efficacy and safety of neoadjuvant chemotherapy in treatment of local- ly advanced carcinoma cervix显示文摘 | Singh U Ahirwar N Rani A K | 2013 | Journal of Obstetrics and Gynaecology of India2013，63，4： | 1 |
| 18 | Impact of nucleotide excision repair ERCC2 and base excision repair APEX1 genes polymorphism and its association with recurrence after adjuvant BCG immunotherapy in bladder cancer patients of North India 显示文摘 | Gangawar R Ahirwar D Mandhani A | 2010 | Med Oncol2010，27，2： | 1 |
| 19 | Patient con- trolled epidural labour analgesia (PCEA) :a comparison between Ropivacaine,Ropivacaine-Fental and Ropiva- caine-Clonidine 显示文摘 | Ahirwar A Prakash R Kashwaha B | 2014 | J Clin Diagn Res2014，8，： | 1 |
| 20 | The efficacy and safety of neoadjuvant chemotherapy in treatment of locally advanced carci- noma cervix显示文摘 | Singh U Ahirwar N Rani AK | 2013 | J Obstet Gynecol India2013，63，4： | 1 |
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