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| 1 | Effect of weathering on physico-chemical properties and combustion behavior of an Indian thermal coal显示文摘An open air stockpile of conical shape was formed with 3.5 m base diameter and 5 m height using 500 tons of -200 mm size ROM thermal coal on a concrete floor. Coal sample from the stockpile were collected at 30 days interval for analysis of various chemical properties like;proximate analysis, ultimate analysis, gross calorific value (GCV) and various combustion related properties such as ignition temperature, peak temperature, burnout temperature, maximum combustion rate, ignition index, burnout index, combustion performance index and combustion rate intensity index. Experimental results show that, due to weathering of coal fixed carbon decreased from 35.6% to 19.9%, elemental carb on (C) decreased from 46.6% to 28.6%, hydrogen (H) decreased from 3.3% to 2.9% and GCV decreased by up to 55% of original value during 330 days of storage of coal in an open atmosphere. Ash con tent of coal increased form 29.2% to 46.6% due to loss of combustibles. Sulfur (S) of coal was found to get increased from 0.33% to 1.08% during storage. The activation energy of coal combustion increased from 22 kJ/mol to 54 kJ/mol. Variation in combustion parameters signifies that weathering has significant negative impact on coal combustion properties as coal become difficult to ignite. | Subhajit Aich Barun Kumar Nandi Sumantra Bhattacharya | 2019 | International Journal of Coal Science & Technology2019，6，1： | 4 |
| 2 | Impact of sodium glucose cotransporter-2 inhibitors on liver steatosis/fibrosis/inflammation and redox balance in non-alcoholic fatty liver disease显示文摘BACKGROUND Sodium glucose cotransporter-2 inhibitors(SGLT2-I)are the most recently approved drugs for type 2 diabetes(T2D).Recent clinical trials of these compounds reported beneficial cardiovascular(CV)and renal outcomes.A major cause of vascular dysfunction and CV disease in diabetes is hyperglycemia associated with inflammation and oxidative stress.Pre-clinical studies demonstrated that SGLT2-I reduce glucotoxicity and promote anti-inflammatory effects by lowering oxidative stress.AIM To investigate the effects of SGLT2-I on markers of oxidative stress,inflammation,liver steatosis,and fibrosis in patients of T2D with non-alcoholic fatty liver disease(NAFLD).METHODS We referred fifty-two consecutive outpatients treated with metformin monotherapy and exhibiting poor glycemic control to our centre.We introduced the outpatients to an SGLT2-I(dapagliflozin,empagliflozin,or canagliflozin;n=26)or a different hypoglycemic drug[other glucose-lowering drugs(OTHER),n=26].We evaluated circulating interleukins and serum hydroxynonenal(HNE)-or malondialdehyde(MDA)-protein adducts,fatty liver index(FLI),NAFLD fibrosis score,aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,AST-to-platelet-ratio index(APRI),and fibrosis-4 on the day before(T0)and following treatment for six months(T1).We also performed transient elastography at T0 and T1.RESULTS Add-on therapy resulted in improved glycemic control and reduced fasting blood glucose in both groups.Of note,following treatment for six months,a reduction of FLI and APRI,as well as of the FibroScan result,was reported in patients treated with SGLT2-I,but not in the OTHER group;furthermore,in the SGLT2-I group,we reported lower circulating levels of interleukin(IL)-1β,IL-6,tumor necrosis factor,vascular endothelial growth factor,and monocyte chemoattractant protein-1,and higher levels of IL-4 and IL-10.We did not observe any modification in circulating interleukins in the OTHER group.Finally,serum HNE-and MDA-protein adducts decreased significantly in SGLT2-I rather than OTHER patients and correlated with liver steatosis and fibrosis scores.CONCLUSION The present data indicate that treatment with SGLT2-I in patients with T2D and NAFLD is associated with improvement of liver steatosis and fibrosis markers and circulating pro-inflammatory and redox status,more than optimizing glycemic control. | Francesco Bellanti Aurelio Lo Buglio MichałDobrakowski Aleksandra Kasperczyk Sławomir Kasperczyk Palok Aich Shivaram P Singh Gaetano Serviddio Gianluigi Vendemiale | 2022 | World Journal of Gastroenterology2022，28，26： | 3 |
| 3 | Tilapia Lake Virus(TiLV)disease:Current status of understanding显示文摘Tilapia Lake Virus(TiLV)disease is an emerging and transboundary disease of tilapia cultures,causing mortality up to 90%globally.TiLV is a negative sense single stranded RNA virus belongs to family Amnoonviridae,genus Tilapinevirus and species Tilapia tilapinevirus.The first TiLV outbreak to fishes was reported from Israel followed by other countries viz.,Ecuador,Colombia,Egypt,Thailand,Chinese Taipei,India,Malaysia,Bangladesh,Uganda,Tanzania,Peru,Mexico,Philippines,Indonesia,and USA.All the life stages of Tilapia(belonging to the family Cichlidae)are vulnerable to TiLV infection.However,river barb and giant gourami have also been found susceptible to TiLV infection.The virus infects the vital organs of the fish,including eyes,brain,and liver.The notable pathological finding of this disease includes syncytial cell formation and massive hepatocellular necrosis with pyknotic and karyolytic nuclei in the liver cells of infected fish.The disease is very contagious and spreads through both horizontal and vertical transmission.Several sensitive and rapid molecular diagnostic tools like reverse transcriptase polymerase chain reaction(RT-PCR),RT-quantitative PCR(RT-qPCR),loop-mediated isothermal amplification(LAMP)have been developed for early detection of the virus.Till date,no comprehensive control measures have been developed throughout the globe,although aggressive work on this line is going on.Implementations of strict good management practices,including quarantine protocols,are the only available option to combat the outbreak and spread of the disease.This review emphasizes the etiology,occurrence and distribution,mode of transmission,pathology and pathogenesis,diagnosis,possible control measures,and challenges of TiLV disease. | Nilav Aich Anirban Paul Tanmoy Gon Choudhury Himadri Saha | 2022 | Aquaculture and Fisheries2022，7，1： | 2 |
| 4 | How does plasmid DNA penetrate cell membranes in artificial transformation process of Escherichia coli 显示文摘 | Panja S Aich P Jana B | 2008 | Mol Membr Biol2008，25，5： | 1 |
| 5 | Flood pro- jections within the Niger River Basin under future land use and climate change 显示文摘 | Valentin Aich Stefan Liersch Tobias Vetter | 2016 | Science of the Total Environment2016，，562： | 1 |
| 6 | Substrate-free Structure of a Monomeric NADP Isocitrate Dehydrogenase: an Open Conformation Phylogenetic Relationship of Isocitrate Dehydrogenase显示文摘 | IMABAYASHI F AICH S PRASAD L | 2006 | Proteins2006，63，1： | 1 |
| 7 | Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a显示文摘 | Sharma A Kumar M Aich J | 2009 | Proc Natl Acad Sci USA2009，106，14： | 1 |
| 8 | Relationship between proximate analysis parameters and combustion behaviour of high ash Indian coal显示文摘This work presents the analysis of combustion characteristics of high ash Indian coal(28%-40%)collected from different mines of Singaurali coalfield,India.All the coal samples were characterized by proximate and gross calorific value analysis.Combustion performance of the coals were characterised using thermo-gravimetric analysis to identify the burning profile of individual coals.Various combustion kinetic parameters such as ignition temperature,peak temperature and burnout temperature,ignition index and burnout index,combustion performance index plus rate and intensity index of combustion process,activation energy were determined to analyse the combustion behaviour of coal.Further all these combustion properties were compared with the volatile matter,ash,fixed carbon and fuel ratio of each coal.Theoretical analysis shows that with increase in ash content,combustion performance initially increases and later descends.Further,coal with(25±1.75)%volatile matter,20%-35%ash and fuel ratio 1.4-1.5 were found to be optimum for coal combustion. | Subhajit Aich Dibyajyoti Behera Barun Kumar Nandi Sumantra Bhattacharya | 2020 | International Journal of Coal Science & Technology2020，7，4： | 1 |
| 9 | Catheter-based renal sympa-thetic denervation for resistant hypertension:a multicentre safety and proof-of-principle cohort study显示文摘 | Krum H Schl aich M Whitbourn R | 2009 | Lancet2009，373，9671： | 1 |
| 10 | Synthetic Resins ⅩⅩⅨ:synthesis and characterisation of the resins derived from 2,4-dinitrophenylhydrazone derivatives of resacetophenone furfural-su bis substituted hydroxy-aromatic compounds显示文摘 | Aich R Lenka S Nayak P L | 1994 | Polymer International1994，34，： | 1 |
| 11 | Multi-modelClimate Impact Assessment and Intercomparison for Three Large-scale River Basins on Three Continents显示文摘 | Vetter T Huang S Aich V | 2014 | Earth System Dynamics Discussions2014，5，2： | 1 |
| 12 | Highly coercive rapidly solidified Sm-Co alloys 显示文摘 | AICH S RAV1NDRAN V K SHIELD J E | 2006 | J Appl Phys2006，99，08： | 1 |
| 13 | Metallic conduction through engineered DNA:DNA nanoelectronic building blocks显示文摘 | Rakitin A Aich P Papadopoulos C | 2001 | Phys Rev Lett2001，86，16： | 1 |
| 14 | Primary fallopian tube carcinoma with metastasis in the contralateral ovary 显示文摘 | Aich RK Dasgupta S Chakraborty B | 2012 | J Indian Med Assoc2012，110，7： | 1 |
| 15 | Electrical and thermoelectric properties of poly ( 2, 7-carbazole) derivatives显示文摘 | Aich R B Blouin N Bouchard A | 2009 | Chem Mater2009，21，4： | 1 |
| 16 | Anterior myocardial infarction with dynamic left ventricular outflow tract obstruction 显示文摘 | Matyal R Wan'aich H J Karhik S | 2011 | Ann Thorac Surg2011，91，3： | 1 |
| 17 | TiB whisker coating on titanium surfaces by solid-state diffusion: synthesis, microstructure, and mechanical 显示文摘 | Aich S Chandran K S | 2002 | Metallurgical & Materials Transactions A2002，33，： | 1 |
| 18 | 查看详情显示文摘 | KESSEDJIAN G JURADO B AICHE M | | 0，，： | 1 |
| 19 | Impact of composite tannery effluent on the amino-transferase activities in a fish biosystem, using guppy fish ( Poecilia reticulata) as an experimental model 显示文摘 | AICH A CHATTOPADHYAY B DATTA S | 2011 | Toxicol Environ Chem2011，93，1： | 1 |
| 20 | Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease显示文摘 | Vasa M Fichtlscherers Aiche A | 2001 | Cir Res2001，89，1： | 1 |
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