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| 1 | 采用冷却倾斜板铸造方法生产悬架零部件用EN Aw 6082铝合金锻坯(英文)显示文摘对采用冷却倾斜板铸造方法生产EN AW 6082铝合金锻坯用于制备悬架零部件的可行性进行研究。采用冷却倾斜板铸造方法生产的EN AW 6082铝合金坯料具有细小的均匀组织,可直接用于锻造生产而不需要另外的均匀化处理。这可能是因为铸造开始时采用较小的过热和冷却倾斜板上发生较多的凝固所致。对采用冷却倾斜板铸造和均匀化处理的含或者不含Cr的EN AW 6082铝合金坯料,通过锻造生产的悬架零部件均具有均匀的组织,经过标准的人工时效处理后硬度可达到HV110。 | Yucel BIROL Seracettin AKDI | 2014 | Transactions of Nonferrous Metals Society of China2014，24，6： | 9 |
| 2 | Involvement and therapeutic implications of airway epithelial barrier dysfunction in type 2 inflammation of asthma显示文摘Type 2 inflammation is a complex immune response and primary mechanism for several common allergic diseases including allergic rhinitis,allergic asthma,atopic dermatitis,and chronic rhinosinusitis with nasal polyps.It is the predominant type of immune response against helminths to prevent their tissue infiltration and induce their expulsion.Recent studies suggest that epithelial barrier dysfunction contributes to the development of type 2 inflammation in asthma,which may partly explain the increasing prevalence of asthma in China and around the globe.The epithelial barrier hypothesis has recently been proposed and has received great interest from the scientific community.The development of leaky epithelial barriers leads to microbial dysbiosis and the translocation of bacteria to inter-and sub-epithelial areas and the development of epithelial tissue inflammation.Accordingly,preventing the impairment and promoting the restoration of a deteriorated airway epithelial barrier represents a promising strategy for the treatment of asthma.This review introduces the interaction between type 2 inflammation and the airway epithelial barrier in asthma,the structure and molecular composition of the airway epithelial barrier,and the assessment of epithelial barrier integrity.The role of airway epithelial barrier disruption in the pathogenesis of asthma will be discussed.In addition,the possible mechanisms underlying the airway epithelial barrier dysfunction induced by allergens and environmental pollutants,and current treatments to restore the airway epithelial barrier are reviewed. | Xiang Dong Mei Ding Jinjin Zhang Ismail Ogülür Yagiz Pat Mübeccel Akdis Yadong Gao Cezmi A.Akdis | 2022 | Chinese Medical Journal2022，，5： | 4 |
| 3 | Mechanisms of allergen-specific immunotherapy显示文摘 | Cezmi A. Akdis Mübeccel Akdis | 2010 | The Journal of Allergy and Clinical Immunology2010，，1： | 2 |
| 4 | MicroRNAs: Essential players in the regulation of inflammation显示文摘 | Ana Rebane Cezmi A. Akdis | 2013 | The Journal of Allergy and Clinical Immunology2013，，1： | 2 |
| 5 | Defective epithelial barrier in chronic rhinosinusitis: The regulation of tight junctions by IFN-γ and IL-4显示文摘 | Michael B. Soyka Paulina Wawrzyniak Thomas Eiwegger David Holzmann Angela Treis Kerstin Wanke Jeannette I. Kast Cezmi A. Akdis | 2012 | The Journal of Allergy and Clinical Immunology2012，，5： | 2 |
| 6 | Immune tolerance in allergy显示文摘 | Akdis M | 2009 | Curr OpinImmunol2009，21，6： | 1 |
| 7 | Thl7 cells in the big picture of immunology显示文摘 | Schmidt-Weber CB Akdis M Akdis CA | 2007 | J Allergy Clin Immunol2007，120，2： | 1 |
| 8 | Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma显示文摘 | Karagiannidis C Akdis M Holopainen P | | 0，，： | 1 |
| 9 | Diagnosis andtreatment of atopic dermatitis in children and adults: euro-pean academy of allergolgy and chinical lmmunology/amer-ican academy of allergy,asthma and lmmunology/PRAC-TALL consensus report 显示文摘 | AKDIS C A’AKDIS M’BIEBER T | 2006 | J Allergy Chlin Immunol2006，118，1： | 1 |
| 10 | Histamine in the immune regulation of al-lergic inflammation 显示文摘 | Akdis CA Blaser K | 2003 | J Allergy Clin Immunol2003，112，1： | 1 |
| 11 | Glucocortieoids upregulate FOXF3 expression eald regulatory T cells in asthma显示文摘 | Karagiannidis C Akdis M Holopainen P | 2004 | J Allergy Clin Immunol2004，114，4： | 1 |
| 12 | Interleukins, from 1 to 37, and interferon : receptors, functions, and roles in diseases 显示文摘 | Akdis M Burg|er S Crameri R | 2011 | J Al- lergy Clin Immuno12011，127，3： | 1 |
| 13 | Immunological mechanisms of allergen -specificimmunotherapy 显示文摘 | Larehe M Akdis CA Valenta R | 2006 | Nat Rev lmmunol2006，6，10： | 1 |
| 14 | Immune regulation by histamine显示文摘 | Jutel M Watanabe T Akdis M | 2002 | Curr Opindmmunol2002，14，6： | 1 |
| 15 | Mechanisms of interleukin-10-mediate immune suppression显示文摘 | Akdis C Blaser K | 2001 | Immunology2001，103，2： | 1 |
| 16 | T regulatory cells and their counterparts:masters of immune regulation显示文摘 | Ozdemir C Akdis M Akdis CA | 2009 | Clin Exp Allergy2009，39，5： | 1 |
| 17 | Mechanisms of interleukin-lO-mediated im- mune suppression 显示文摘 | Akdis C A Blaser K | 2001 | Immunology2001，103，2： | 1 |
| 18 | Mechanisms of subcutane- ous allergen immunotherapy 显示文摘 | Soyer OU Akdis M Akdis CA | 2011 | Immunol Allergy Clin North Am2011，31，2： | 1 |
| 19 | Pimecrolimus,a topical calcineurin inhibitor used in the treatment of atopic eczema显示文摘 | Prucha H Schnopp C Akdis C | 2013 | Expert Opin Drug Metab Toxicol2013，9，11： | 1 |
| 20 | Mechanisms of allergen specific immunotherapy显示文摘 | Akdis CA Blaser K | 2000 | Allergy2000，55，6： | 1 |
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