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408篇 您的检索式:作者名="Alan E"
    题名 作者 年代 出处 被引量
1Progress in carbon dioxide separation and capture: A review显示文摘这篇文章考察在 CO2 分离和俘获研究和工程取得的进步。各种各样的技术例如吸收,吸附,和膜分离,彻底地被讨论。象化学循环的燃烧和基于水合物的分离那样的新概念也简短被介绍。未来方向被建议。隐遁方法海洋授精和矿物质碳酸饱和技术例如造林,也被盖住。地下的注射和直接海洋垃圾场没被盖住。Hongqun Yang Zhenghe Xu Maohong Fan Rajender Gupta Rachid B Slimane Alan E Bland Ian Wright 2008Journal of Environmental Sciences2008,20,1:89
2Necrotizing enterocolitis: A multifactorial disease with no cure显示文摘Necrotizing enterocolitis is an inflammatory bowel disease of neonates with significant morbidity and mortality in preterm infants. Due to the multifactorial nature o the disease and limitations in disease models, early diagnosis remains challenging and the pathogenesis elusive. Although preterm birth, hypoxic-ischemic events formula feeding, and abnormal bacteria colonization are established risk factors, the role of genetics and vasoactive/inflammatory mediators is unclear Consequently, treatments do not target the specific underlying disease processes and are symptomatic and surgically invasive. Breast-feeding is the most effective preventative measure. Recent advances in the prevention of necrotizing enterocolitis have focused on bioactive nutrients and trophic factors in human milk. Developmen of new disease models including the aspect of prematurity that consistently predisposes neonates to the disease with multiple risk factors will improve our understanding of the pathogenesis and lead to discovery of innovative therapeutics.Kareena L Schnabl John E Van Aerde Alan BR Thomson Michael T Clandinin 2008World Journal of Gastroenterology2008,14,14:19
3Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life.Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam 2013World Journal of Gastroenterology2013,19,46:6
4Nutritional modulation of the inflammatory response in inflammatory bowel disease-From the molecular to the integrative to the clinical显示文摘Nutrient deficiencies are common in patients with inflammatory bowel disease (IBD). Both total parenteral and enteral nutrition provide important supportive therapy for IBD patients, but in adults these are not useful for primary therapy. Dietary intervention with omega-3 polyunsaturated fatty acids contained in fish oil may be useful for the care of IBD patients, and recent studies have stressed the role of PPAR on NFκB activity on the potential beneficial effect of dietary lipids on intestinal function.Gary E Wild Laurie Drozdowski Carmela Tartaglia M Tom Clandinin Alan BR Thomson 2007World Journal of Gastroenterology2007,13,1:6
5Vector-mode multiplexing brings an additional approach for capacity growth in optical fibers显示文摘The paper‘Direct fiber vector eigenmode multiplexing transmission seeded by integrated optical vortex emitters’by J Liu1 has successfully demonstrated that different data-carrying vector modes can be used to increase capacity through data-carrying,full-vectorial fiber eigenmode multiplexing communications in circular optical fibers.This work uses compact,integrated optics to achieve capacity scaling by directly exploiting orthogonal spatial vector eigenmodes.Alan E Willner 2018Light(Science & Applications)2018,7,1:5
6腹主动脉瘤腔内隔绝术后继发性内漏的原因和处理显示文摘与传统开放手术相比,应用腔内隔绝术或称腔内修复术(endovascular aneurysm repair,EVAR)治疗腹主动脉瘤(abdominal aortic aneurysm,AAA)具有手术创伤小、术后恢复快、住院时间短等优点,但其特有并发症内漏到目前还无法完全避免。内漏按其发生机制被分为Ⅰ~Ⅳ型,从发生时间来分又可分为原发性内漏和继发性内漏。我们将通过介绍几个病例的处理,对EVAR术后继发性内漏的发生原因、处理指征和处理方法进行探讨。包俊敏 Alan E Bray 景在平 2007中华外科杂志2007,45,17:4
7Quality Improvement Guidelines for the Treatment of Lower Extremity Deep Vein Thrombosis with Use of Endovascular Thrombus Removal显示文摘Suresh Vedantham Patricia E. Thorpe John F. Cardella Clement J. Grassi Nilesh H. Patel Hector Ferral Lawrence V. Hofmann Bertrand M. Janne d’Othée Vittorio P. Antonaci Elias N. Brountzos Daniel B. Brown Louis G. Martin Alan H. Matsumoto Steven G. Meranze 2006Journal of Vascular and Interventional Radiology2006,,3:3
8Hemoglobin A1c in early postpartum screening of women with gestational diabetes显示文摘AIM:To assess the utility of hemoglobin A1c(HbA1c) in the early postpartum screening of women with gestational diabetes mellitus(GDM).METHODS:Over a 3 years period,HbA1c estimations were undertaken in addition to and simultaneously with the traditional oral glucose tolerance test(OGTT),in 203 women with GDM as a part of early postpartum screening for dysglycaemia,at 6 wk post-partum.World Health Organization criteria was used for diagnosing diabetes:fasting blood glucose(FBG) ≥ 7.0 mmol/Land/or 2-h postprandial blood glucose(PPBG) ≥ 11.1 mmol/L and/or HbA1c ≥ 48 mmol/mol;and impaired glycaemiastate:impaired fasting glucose 6.1-6.9 mmol/L and/or impaired glucose tolerance 7.8-11.0 mmol/L and/or HbA1c:42-47 mmol/mol.RESULTS:Mean FBG,2-h PPBG and HbA1c were 4.9 ± 0.7 mmol/L,5.6 ± 2.0 mmol/L and 38 ± 5 mmol/mol respectively.FBG,2-h PPBG and HbA1c detected 6(3%),7(3.5%) and 11(5.4%) cases of diabetes respectively,and 11(5.4%),25(12.3%) and 23(11.3%) cases of pre-diabetes state respectively.HbA1c values ≥ 48 mmol/mol(≥ 6.5%) showed a diagnostic sensitivity of 71.4% and specificity of 98.5% for diabetes in comparison to OGTT in receiver operating characteristics curve analysis.At HbA1c cut-off 44 mmol/mol,sensitivity and specificity were 100% and 92.3% respectively [area under the curve:0.98(95%CI:0.96-1.00)].Sensitivity and specificity for detecting high risk 'impaired glycaemia' state [HbA1c 42 mmol/mol(6.0%)] were 28% and 80%,respectively.CONCLUSION:HbA1c level ≥ 48 mmol/mol(≥ 6.5%) has reasonable sensitivity and high specificity in comparison to OGTT for early postpartum screening of diabetes in GDM.At 6 th week postpartum screening,if FBG is normal and HbA1c < 44 mmol/mol OGTT is not recommended.Mahesh V Katreddy Joseph M Pappachan Sarah E Taylor Radha Indusekhar Ananth U Nayak Alan M Nevill 2013World Journal of Diabetes2013,4,3:2
9Downscaling future climate scenarios to fine scales for hydrologic and ecological modeling and analysis显示文摘Introduction:Evaluating the environmental impacts of climate change on water resources and biological components of the landscape is an integral part of hydrologic and ecological investigations,and the resultant land and resource management in the twenty-first century.Impacts of both climate and simulated hydrologic parameters on ecological processes are relevant at scales that reflect the heterogeneity and complexity of landscapes.At present,simulations of climate change available from global climate models[GCMs]require downscaling for hydrologic or ecological applications.Methods:Using statistically downscaled future climate projections developed using constructed analogues,a methodology was developed to further downscale the projections spatially using a gradient-inverse-distancesquared approach for application to hydrologic modeling at 270-m spatial resolution.Results:This paper illustrates a methodology to downscale and bias-correct national GCMs to subkilometer scales that are applicable to fine-scale environmental processes.Four scenarios were chosen to bracket the range of future emissions put forth by the Intergovernmental Panel on Climate Change.Fine-scale applications of downscaled datasets of ecological and hydrologic correlations to variation in climate are illustrated.Conclusions:The methodology,which includes a sequence of rigorous analyses and calculations,is intended to reduce the addition of uncertainty to the climate data as a result of the downscaling while providing the fine-scale climate information necessary for ecological analyses.It results in new but consistent data sets for the US at 4 km,the southwest US at 270 m,and California at 90 m and illustrates the utility of fine-scale downscaling to analyses of ecological processes influenced by topographic complexity.Lorraine E Flint Alan L Flint 2012Ecological Processes2012,1,1:2
10Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis显示文摘Min Jun Celine Foote Jicheng Lv Bruce Neal Anushka Patel Stephen J Nicholls Diederick E Grobbee Alan Cass John Chalmers Vlado Perkovic 2010The Lancet . 2010 (9729)2010,,9729:2
112011 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Peripheral Artery Disease (Updating the 2005 Guideline)显示文摘Thom W. Rooke Alan T. Hirsch Sanjay Misra Anton N. Sidawy Joshua A. Beckman Laura K. Findeiss Jafar Golzarian Heather L. Gornik Jonathan L. Halperin Michael R. Jaff Gregory L. Moneta Jeffrey W. Olin James C. Stanley Christopher J. White John V. White R. E 2011Journal of the American College of Cardiology2011,,:2
12Monetary Shocks and Relative Farm Prices: A Re-examination 显示文摘saac Alan G David E Rapach 1997American Journal of Agricultural Economics1997,,4:1
13Personalized and not general suggestion produces false autobiographical memories and suggestion-consistent behavior显示文摘Alan Scoboria Giuliana Mazzoni Josée L. Jarry Daniel M. Bernstein 2011Acta Psychologica2011,,1:1
14Expression of vascular en- dothelial growth factor receptors and their ligands in rat ute- rus during the postpartum involution period 显示文摘Sagsoz H Liman N Alan E 2015Biotech Histochem2015,,:1
15A randomised controlled trial investigating the effect of n-3 long-chain polyunsaturated fatty acid supplementation on cognitive and retinal function in cognitively healthy older people: the Older People And n-3 Long-chain polyunsaturated fatty acids(OPAL) study protocol显示文摘Alan D D Felicity C Diana E 2006Nutrition Journal2006,20,5:1
16Interaction of trans-diamminedichloroplatinum (Ⅱ) with DNA: formation of monofunctional adducts and their reaction with glutathione显示文摘Alan E Michael A B 1987Biochemistry1987,26,12:1
17Absolute levels of tran- scripts for mitochondrial uncoupling proteins UCP-2, UCP-3, UCP- 4, and UCP-5 show different patterns in rat and mice tissues 显示文摘Alan L Smolkova K Kronusova E 2009Bioenerg Biomembr2009,41,:1
18Deposition of anatase on the surface of activated carbon显示文摘AMJAD H E S ALAN P N HAFID A D 2004Surface Coatings Technology2004,187,23:1
19The effect of co-occurring inorganic solutes on the removal of arsenic(V)from water using cationic surfactant micelles and an ultrafihration membrane显示文摘ERDOGAN E HATICE G ALAN F 2005Desalination2005,181,13:1
20Competitive formation of polymer cyclodextrin inclusion compounds显示文摘Cristian C Rusa Justin Fox Alan E Tonelli 2003Macromolecules2003,36,:1
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