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| 1 | Continuous wound infusion of local anaesthetic agents following colorectal surgery:Systematic review and meta-analysis显示文摘AIM:To provide a specifi c review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparoto-my for major colorectal surgery. METHODS: Medline, Embase, trial registries, conference proceedings and article reference lists were searched to identify randomised, controlled trials of continuous wound infusion of local anaesthetic agents following colorectal surgery. The primary outcomes were opioid consumption, pain visual analogue scores (VASs), return to bowel function and length of hospital stay. Weighted mean difference were calculated for continuous outcomes. RESULTS: Five trials containing 542 laparotomy wounds were eligible for inclusion. There was a sig- nificant decrease in post-operative pain VAS at rest on day 3 (weighted mean difference: -0.43; 95% CI: -0.81 to -0.04; P = 0.03) but not on post-operative day 1 and 2. Local anaesthetic infusion was associated with a signifi cant reduction in pain VAS on movement on all three post-operative days (day 1 weighted mean difference: -1.14; 95% CI: -2.24 to -0.041; P = 0.04, day 2 weighted mean difference: -0.97, 95% CI: -1.91to -0.029; P = 0.04, day 3 weighted mean difference: -0.61; 95% CI: 1.01 to -0.20; P = 0.0038). Local an- aesthetic wound infusion was associated with a signifi - cant decrease in total opioid consumption (weighted mean difference: -40.13; 95% CI: -76.74 to -3.53; P = 0.03). There was no signifi cant decrease in length of stay (weighted mean difference: -20.87; 95% CI: -46.96 to 5.21; P = 0.12) or return of bowel function (weighted mean difference: -9.40; 95% CI: -33.98 to 15.17; P = 0.45). CONCLUSION: The results of this systematic re- view and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major color- ectal surgery is a promising technique but do not pro- vide conclusive evidence of benefi t. Further research is required including cost-effectiveness analysis. | Alan Karthikesalingam Stewart R Walsh Sheraz R Markar Umar Sadat Tjun Y Tang Charles M Malata | 2008 | World Journal of Gastroenterology2008,14,34: | 4 |
| 2 | 新加坡成人慢性呼吸系统疾病患者6分钟步行距离的最小临床重要差异值研究(英文)显示文摘目的:6 min步行距离(6MWD)是临床上常见的功能性运动能力测试,特别是对于慢性呼吸系统疾病患者。一些文献记载了关于白种人的6MWD的最小临床重要差异(MCID),但对亚洲人群的相关信息未见记载。本研究旨在建立亚洲成人慢性呼吸道疾病患者6MWD的最小临床重要差异。方法:采用'锚定'法和'分布'法对新加坡中央医院肺康复计划登记处的资料进行了分析。'锚定'法收集确诊为慢性呼吸道疾病的患者50例,其中男38例,女12例;平均年龄(64.2±12.3)岁,通过电话采访及使用整体变化评估量表(GROC)评价患者肺康复计划后的自觉改善程度,再将患者在肺康复计划中6MWD的改变数值与相对应的患者自觉改善程度进行比较,这种关系用操作特征曲线(ROC)统计表示。通过'分布'法确定6MWD的MCID,从门诊和住院的肺康复计划(PRP)参与者中检索医疗记录136例,其中男103例,女33例;平均年龄(60.1±14.1)岁。结果 :ROC曲线表明6MWD出现临床显著性变化的最佳临界值为17.4 m,其对应的敏感性为79.4%,特异性为81.3%,阳性似然比为4.23。由'分布'法确定6MWD的最小临床重要差异值为18.6 m。结论:18.6 m为新加坡华人6MWD的最小临床重要差异的估计值。 | Meredith T L YEUNG Alan W P WONG Katherine S L HUANG Alice Y M JONES | 2015 | 康复学报2015,25,1: | 3 |
| 3 | Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression显示文摘 | Yoo Byoung Kwon Emdad Luni Su Zao-zhong Villanueva Augusto Chiang Derek Y Mukhopadhyay Nitai D Mills Alan Scott Waxman Samuel Fisher Robert A Llovet Josep M Fisher Paul B Sarkar Devanand | 2009 | Journal of Clinical Investigation2009,,3: | 2 |
| 4 | Principle of non-contacting infrared temperature measurement 显示文摘 | Alan M Y | 1998 | Proceedings of the International Symposium1998,44,: | 1 |
| 5 | Convergence properties of the softassign quadratic assignment algorithm 显示文摘 | ANAND R ALAN Y ERIC M | 1999 | Neural Computation1999,11,: | 1 |
| 6 | Real-life Energy Use in the UK:How Occupancy and Dwelling Characteristics Affect Domestic Electricity Use显示文摘 | YIGZAW G Y JAYANTA D M ALAN W | 2008 | Energy and Buildings2008,40,6: | 1 |
| 7 | Posterolateral transfo raminal selective endoscopic discectomy and thermal annuloplasty for chronic lumbar discogenic pain=a minimal access visualized in tradiscal surgical procedure显示文摘 | TSOU P M ALAN Y C YEUNG A T | 2004 | Spine J2004,4,5: | 1 |
| 8 | Detection of a small lung cancer hidden in pneumoeoniosis with progressive massive fibrosis using F-18 fluorodeoxyglueose PET/CT 显示文摘 | Je S K Im Alan M Park Y H | 2007 | Clinical nuclear medicine2007,32,3: | 1 |
| 9 | 显示文摘 | Song M Y Alan D S Park H R | 1999 | Journal of Power Sources1999,83,12: | 1 |
| 10 | Social and spatial implications of housing reform in China显示文摘 | WANG Y ALAN M | 2000 | International Journal of Urban and regional Research2000,24,2: | 1 |
| 11 | Self-assembly of mesoscopicatly ordered chromatic polydiacetylene/silica nanocomposites显示文摘 | Lu Y F Yi Y Alan A Lu M C | 2001 | Nature2001,410,: | 1 |
| 12 | Evaluation on the adsorptioncapabilities of new chemically modified polymeric adsorbents with protoporphyrin IX 显示文摘 | Jung M W Alan K H Lee Y | 2001 | Joumal of Chromatography A2001,917,1: | 1 |
| 13 | Differential roles of Arabidopsis heterotrimeric G-protein subunits in modulating cell division in roots显示文摘 | Chen J G Gao Y J Alan M | 2006 | Plant Physiology2006,141,: | 1 |
| 14 | Risk factors for failure of initial intravenous immunoglobulin treatmem in Kawasaki disease 显示文摘 | Cha S Yoon M Alan Y | 2008 | J Korean Med Sci2008,23,4: | 1 |
| 15 | Hydrolysis and acidogenesis of particulate organic material in mesophilic and thermophilic anaerobic digestion 显示文摘 | Kim M Gomec C Y Alan Y | 2003 | Environmental Technology2003,24,9: | 1 |
| 16 | ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis显示文摘 | CHEN J G HEMAYET U JEFFERY C Y MICHAEL R S ALAN M J | 2001 | Genes &Development2001,15,: | 1 |
| 17 | 显示文摘 | Xia Y N Wiesinger J M Alan G | 1995 | Chem Mater1995,7,: | 1 |
| 18 | Rapid measurement of B-tyoe natriuretic peptide in the emergency diagnosis of heart failure显示文摘 | ALAN S MAISEL M D PADMA K Y | 2002 | N Engl J Med2002,347,: | 1 |
| 19 | Location and structure of coke generated over Pt-Sn/AlzO3 in propane dehydrogenation 显示文摘 | Vu B K Song M B Alan I Y | 2011 | JlndEngChem2011,17,1: | 1 |
| 20 | The Effect of Relationship Marketing Orientation on Business Performance in A Service-Oriented Economy显示文摘 | Leo Y M Sin Alan C B Tse Oliver H M Yau | 2002 | Journal of Services Marketing2002,16,7: | 1 |