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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Dietary approaches following endoscopic retrograde cholangiopancreatography: A survey of selected endoscopists显示文摘AIM: To describe the dietary recommendations of experienced endoscopists for patients who have undergone endoscopic retrograde cholangiopancreatography (ERCP) and the factors that influence these recommendations. METHODS: Selected U.S. endoscopists with ERCP experience were surveyed by e-mail. A questionnaire with three hypothetical ERCP cases of patients at low, medium and high risk for development of post-ERCP pancreatitis (PEP) was shown. For each scenario, respondents were asked to recommend a post-procedure diet and time to first oral intake. Respondents were also asked about the effect of various clinical factors on their recommendations, including risk of PEP.RESULTS: 97/187 selected ASGE members (51.9%) responded. When risk of PEP was either low, medium or high, 53%, 88% and 96% recommended a diet of clear liquids/NPO respectively, and 2%, 5% and 18% recommended delaying first oral intake until the following day. About 88% of respondents gave the same type of diet to patients at high as those with moderate-risk of PEP (P = 0.04). However, 37% and 43% of respondents gave different types of diet to patients at low vs moderate-risk and low-risk vs high-risk of PEP respectively (P < 0.001). No statistically significant associations were found regarding the effect of other clinical factors or respondent demographics.CONCLUSION: Most experienced endoscopists limit diet to NPO/clear liquids after ERCP for patients at high or moderate risk of post-ERCP pancreatitis. About half allow a low-fat or regular diet in patients at low risk. | Lincoln EVVC Ferreira Mark D Topazian William S Harmsen Alan R Zinsmeister Todd H Baron | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，12： | 3 |
| 3 | Listeria monocytogenes following orthotopic liver transplantation:Central nervous system involvement and review of the literature显示文摘Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals,including solid organ transplant recipients,but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy,and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis,and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis. | Shugo Mizuno Ivan R Zendejas Alan I Reed Robin D Kim Richard J Howard Alan W Hemming Denise C Schain Consuelo Soldevila-Pico Roberto J Firpi Shiro Fujita | 2007 | World Journal of Gastroenterology2007，13，32： | 2 |
| 4 | China' s Rural Labor Market De- velopment and its Gender Implications 显示文摘 | Brauw Alan D Scott R | 2004 | China Economic Review2004，15，2： | 1 |
| 5 | Interleukin-18 enhances athero-sclerosis in apolipoprotein E-/-Mice through release of interferon-γ显示文摘 | Stewart CW Punnaivanam R Alan D | 2002 | Circ Res2002，90，2： | 1 |
| 6 | Competing models of entrepreneurial intentions显示文摘 | Krueger J R Norris F Reilly Michael D and Carsrud Alan L | 2000 | Journal of Business Venturing2000，15，56： | 1 |
| 7 | A test method for wash-off pressure sensitive adhesives显示文摘 | BRYAN D L ALAN D R P | 1996 | International Journal of Adhesion and Adhesives1996，16，1： | 1 |
| 8 | Estimates of the elasticities of substitution between imports and home goods for the United States显示文摘 | Clinton R S Robert M S Alan V D | | 0，，03： | 1 |
| 9 | Valuing increments and decrements in natural resource service flows 显示文摘 | BROOKSHIRE D ALAN R JOHN S | 1980 | American journal of agricultural economics1980，62，3： | 1 |
| 10 | Obesitygene variant and elite endurance performance显示文摘 | Moore Geoffrey E Shuldiner Alan R Zmuda J0seph M Ferrell Robert E Mccole Steve D Hagberg James M | 2001 | Metabolism Clinical and Experimental2001，50，12： | 1 |
| 11 | Effect of Sur- face Finish on Gear Tooth Friction 显示文摘 | Britton R D Elcoate C D Alanou M P | 2000 | Journal of tribology2000，122，1： | 1 |
| 12 | Effect of granulocyte-monocyte colony-stimulating factor therapy on leukocyte function and clearance of serious infection in nonneutropenic patients显示文摘 | Alan J R Peter K L Adrienne D | 2005 | Chest2005，127，： | 1 |
| 13 | A novel seri es of 2,5-substituted tryptamine derivative as vascular 5-HT 1B/D recepto r antagonists显示文摘 | Gerar P Molone Alan D Robertson Graeme R Martin | 1997 | J Med Chem1997，40，： | 1 |
| 14 | Microwave pyrolysis,a novel process for recycling waste automotive engine oil显示文摘 | SU S L ALAN D R HOWARD A C | | 0，，35： | 1 |
| 15 | Evaluating national cause-of-death statistics : Principles and application to the case of Chi- na显示文摘 | CHALAPATI R ALAN D GONGHUAN Y | 2005 | Bull World Health Organ2005，83，8： | 1 |
| 16 | In vivo tracking of platelets:Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function显示文摘 | Marc R B Herbert B H | 1996 | Med Sci1996，93，11： | 1 |
| 17 | 显示文摘 | Song M Y Alan D S Park H R | 1999 | Journal of Power Sources1999，83，12： | 1 |
| 18 | Biloxi Interstate 110 Voaduct显示文摘 | Alan R Phipps Q D Spruill Jr | 1990 | PCI Journal1990，，12： | 1 |
| 19 | The effect of medial meniscectomy and coronal plane angulation on in vitro load transmission in the canine stifle joint 显示文摘 | Alan P N Anderson D R | 1989 | Orthopaedic Research1989，7，： | 1 |
| 20 | Enzyme-containing mi- chael -- Adduet-based coatings 显示文摘 | G6raldine F D Claus U Alan J R | 2003 | Biomacromolecules2003，4，： | 1 |
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