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| 1 | Simultaneous intraductal papillary neoplasms of the bile duct and pancreas treated with chemoradiotherapy显示文摘Some authors have suggested that intraductal papillary mucinous neoplasms of the bile duct(IPMN-B) could be the the biliary counterpart of IPMN of the pancreas(IPMN-P) since they share several clinical-pathological features.These include prominent intraductal papil-lary proliferation pattern,a gastrointestinal phenotype,frequent mucin hyper-secretion and progression to mu-cinous carcinoma.To date there are just four reported cases of patients with synchronous IPMN-B and IPMN-P all of which were treated surgically.We hereby report the case of a 76-year-old woman who was incidentally diagnosed with both an asymptomatic 3 cm bulky uid lesion obstructing the bile duct lumen,diagnosed as a malignant IPMN-B,and synchronous multiple pancreatic cystic lesions(10-13 mm) communicating with an irreg-ular Wirsung,diagnosed as branch duct IPMN-P.Since surgery was ruled-out because of the patient's age and preferences,she underwent a conservative manage-ment regimen comprising both chemotherapy and radio-therapy.This was effective in decreasing the mass size and in resolving subsequent jaundice.This is also the f irst reported case of IPMN-B successfully treated with chemoradiotherapy.Clinicians should consider medical treatment as an option in this clinical scenario,in pa-tients who may be unf it for surgery. | Roberto Valente Gabriele Capurso Paola Pierantognetti Elsa Iannicelli Matteo Piciucchi Adriana Romiti Paolo Mercantini Alberto Larghi Giulia Francesca Federici Viola Barucca Maria Falchetto Osti Emilio Di Giulio Vincenzo Ziparo Gianfranco Delle Fave | 2012 | World Journal of Gastrointestinal Oncology2012，4，2： | 13 |
| 2 | The role of K- ras gene mutation analysis in EUS-guided FNA cytology specimens for the differential diagnosis of pancreatic solid masses: a meta-analysis of prospective studies显示文摘 | Lorenzo Fuccio Cesare Hassan Liboria Laterza Loredana Correale Nico Pagano Paolo Bocus Carlo Fabbri Antonella Maimone Vincenzo Cennamo Alessandro Repici Guido Costamagna Franco Bazzoli Alberto Larghi | 2013 | Gastrointestinal Endoscopy2013，，： | 4 |
| 3 | Feasibility and yield of a novel 22-gauge histology EUS needle in patients with pancreatic masses: a multicenter prospective cohort study显示文摘 | Alberto Larghi Julio Iglesias-Garcia Jan-Werner Poley Geneviève Monges Maria Chiara Petrone Guido Rindi Ihab Abdulkader Paolo Giorgio Arcidiacono Guido Costamagna Katharina Biermann Erwan Bories Claudio Doglioni J. Enrique Dominguez-Mu?oz Cesare Hassan Ma | 2013 | Surgical Endoscopy2013，，10： | 3 |
| 4 | Successful endoscopic closure of a lateral duodenal perforation at ERCP with fibrin glue显示文摘 | Massimiliano Mutignani Federico Iacopini Stefanos Dokas Alberto Larghi Pietro Familiari Andrea Tringali Guido Costamagna | 2006 | Gastrointestinal Endoscopy2006，，4： | 2 |
| 5 | Endoscopic direct cholangioscopy by using an ultra-slim upper endoscope: a feasibility study显示文摘 | Alberto Larghi Irving Waxman | 2006 | Gastrointestinal Endoscopy2006，，6： | 2 |
| 6 | Endoscopic ultrasound fine needle aspiration:Technique and applications in clinical practice显示文摘Since its initial report in 1992,endoscopic ultrasoundguided fine needle aspiration(EUS-FNA) has now been incorporated into the diagnostic and staging algorithm for the evaluation of benign and malignant diseases of the gastrointestinal tract and of adjacent organs.Its introduction constitutes a major breakthrough in the endoscopic field and has gradually transformed EUS from a pure imaging modality into a more interventional procedure.In addition,the possibility of collecting samples,providing a definitive cytological and/or histological evidence of the presence of malignancy,has strongly contributed to changing EUS from a subjective,highly operator dependant procedure into a more objective one.This article will review the instrumentation,technique and the most important clinical applications of EUS-FNA. | Benjamin Tharian Fotios Tsiopoulos Nayana George Salvatore Di Pietro Fabia Attili Alberto Larghi | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，12： | 2 |
| 7 | Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies显示文摘 | Alberto Larghi Massimo Zuin Andrea Crosignani Maria Lisa Ribero Cristina Pipia Pier Maria Battezzati Giorgio Binelli Francesco Donato Alessandro Remo Zanetti Mauro Podda Alessandro Tagger | 2002 | Hepatology2002，，4： | 1 |
| 8 | Performance of the forward-viewing linear echoendoscope for fine-needle aspiration of solid and cystic lesions throughout the gastrointestinal tract: a large single-center experience显示文摘 | Alberto Larghi Lorenzo Fuccio Fabia Attili Ester Diana Rossi Matteo Napoleone Domenico Galasso Guido Fadda Guido Costamagna | 2014 | Surgical Endoscopy2014，，6： | 1 |
| 9 | Cellular and molecular pathways linking inflammation and cancer显示文摘 | Chiara Porta Paola Larghi Monica Rimoldi Maria Grazia Totaro Paola Allavena Alberto Mantovani Antonio Sica | 2009 | Immunobiology2009，，9： | 1 |
| 10 | EUS-guided fine-needle tissue acquisition by using a 19-gauge needle in a selected patient population: a prospective study显示文摘 | Alberto Larghi Elizabeth C. Verna Riccardo Ricci Tom C. Seerden Domenico Galasso Antonella Carnuccio Naohito Uchida Guido Rindi Guido Costamagna | 2011 | Gastrointestinal Endoscopy2011，，3： | 1 |
| 11 | Endoscopic Mucosal Resection: Treatment of Neoplasia显示文摘 | Alberto Larghi Irving Waxman | 2005 | Gastrointestinal Endoscopy Clinics of North Americ2005，，： | 1 |
| 12 | Endoscopic ultrasound-guided gallbladder drainage in pancreatic cancer and cholangitis: A case report显示文摘BACKGROUND Head pancreatic cancers often present with clinical challenges requiring biliary drainage for chemotherapy or palliative scope.If usual endoscopic modalities fail or if percutaneous approach is not feasible,endoscopic ultrasound(EUS)guided biliary drainage can be considered.Here we describe and discuss an interesting clinical case in which EUS-guided gallbladder drainage(EUS-GBD)was chosen to treat acute severe cholangitis in a patient with advanced pancreatic cancer.CASE SUMMARY An 84-year-old female with a previous EUS-biopsy proven diagnosis of head pancreatic cancer presented with clinical signs of acute cholangitis.In September 2018 she had positioned a biliary and duodenal stent to relieve jaundice and an initial duodenal substenosis.In the emergency ward,an abdominal computed tomography scan showed proximal biliary stent occlusion due to neoplastic progression,but endoscopic retrograde cholangiopancreatography was impossible because of worsening duodenal stenosis and the absence of a chance to reach the Vater’s papilla area.EUS-guided choledocoduodenostomy was not technically feasible but because the cystic duct was free of neoplastic infiltration,an EUS-GBD using an Axios^TM stent was successfully performed.The patient started to feed after 48 h and was discharged 1 wk later.No other hospitalizations due to cholangitis or symptoms of Axios^TM stent occlusion/dysfunction were observed up until her death 6 mo later due to underlying disease.CONCLUSION This case demonstrated how different EUS therapeutic approaches could have a key role to treat critical and seemingly unsolvable situations and that they could play a more fundamental role in the next future. | Germana de Nucci Nicola Imperatore Desiree Picascia Enzo Domenico Mandelli Cristina Bezzio Ilaria Arena Barbara Omazzi Alberto Larghi Gianpiero Manes | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，11： | 1 |
| 13 | Interobserver agreement among pathologists regarding core tissue specimens obtained with a new endoscopic ultrasound histology needle; a prospective multicentre study in 50 cases显示文摘 | Maria Chiara Petrone Jan‐Werner Poley Matteo Bonzini Pier Alberto Testoni Ihab Abdulkader Katharina Biermann Genevieve Monges Guido Rindi Claudio Doglioni Marco J Bruno Marc Giovannini Julio Iglesias‐Garcia Alberto Larghi Paolo Giorgio Arcidiacono | 2013 | Histopathology2013，，4： | 1 |
| 14 | Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study显示文摘 | Julio Iglesias-Garcia Jan-Werner Poley Alberto Larghi Marc Giovannini Maria Chiara Petrone Ihab Abdulkader Genevieve Monges Guido Costamagna Paolo Arcidiacono Katharina Biermann Guido Rindi Erwan Bories Claudio Dogloni Marco Bruno J. Enrique Dominguez-Mu? | 2011 | Gastrointestinal Endoscopy2011，，6： | 1 |
| 15 | Hemostasis of Dieulafoy’s lesions by argon plasma coagulation (with video) 显示文摘 | Federico Iacopini Lucio Petruzziello Michele Marchese Alberto Larghi Cristiano Spada Pietro Familiari Andrea Tringali Maria Elena Riccioni Armando Gabbrielli Guido Costamagna | 2007 | Gastrointestinal Endoscopy2007，，： | 1 |
| 16 | Outcome of an outbreak of acute hepatitis C among healthy volunteers participating in pharmacokinetics studies显示文摘 | Alberto Larghi Massimo Zuin Andrea Crosignani Maria Lisa Ribero Cristina Pipia Pier Maria Battezzati Giorgio Binelli Francesco Donato Alessandro Remo Zanetti Mauro Podda Alessandro Tagger | 2002 | Hepatology2002，，4： | 1 |
| 17 | EUS followed by EMR for staging of high-grade dysplasia and early cancer in Barrett’s esophagus显示文摘 | Alberto Larghi Charles J. Lightdale Lorenzo Memeo Govind Bhagat Nnenna Okpara Heidrun Rotterdam | 2005 | Gastrointestinal Endoscopy2005，，： | 1 |
| 18 | Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study显示文摘 | Julio Iglesias-Garcia Jan-Werner Poley Alberto Larghi Marc Giovannini Maria Chiara Petrone Ihab Abdulkader Genevieve Monges Guido Costamagna Paolo Arcidiacono Katharina Biermann Guido Rindi Erwan Bories Claudio Dogloni Marco Bruno J. Enrique Dominguez-Mu? | 2011 | Gastrointestinal Endoscopy2011，，6： | 1 |
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