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| 1 | Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors显示文摘Long non-coding RNAs(lncRNAs)are members of the non-protein coding RNA family longer than 200 nucleotides.They participate in the regulation of gene and protein expression influencing apoptosis,cell proliferation and immune responses,thereby playing a critical role in the development and progression of various cancers,including colorectal cancer(CRC).As CRC is one of the most frequently diagnosed malignancies worldwide with high mortality,its screening and early detection are crucial,so the identification of disease-specific biomarkers is necessary.LncRNAs are promising candidates as they are involved in carcinogenesis,and certain lncRNAs(e.g.,CCAT1,CRNDE,CRCAL1-4)show altered expression in adenomas,making them potential early diagnostic markers.In addition to being useful as tissue-specific markers,analysis of circulating lncRNAs(e.g.,CCAT1,CCAT2,BLACAT1,CRNDE,NEAT1,UCA1)in peripheral blood offers the possibility to establish minimally invasive,liquid biopsy-based diagnostic tests.This review article aims to describe the origin,structure,and functions of lncRNAs and to discuss their contribution to CRC development.Moreover,our purpose is to summarise lncRNAs showing altered expression levels during tumor formation in both colon tissue and plasma/serum samples and to demonstrate their clinical implications as diagnostic or prognostic biomarkers for CRC. | Orsolya Galamb Barbara K Barták Alexandra Kalmár Zsófia B Nagy Krisztina A Szigeti Zsolt Tulassay Peter Igaz Béla Molnár | 2019 | World Journal of Gastroenterology2019，25，34： | 18 |
| 2 | The science behind lutein 显示文摘 | ALEXANDRA A R ANDREW S | 2004 | Toxicol Lett2004，150，： | 1 |
| 3 | Lay- er-by-layer engineered capsules and their applications 显示文摘 | ANGUS P R J CHRISTINA C ALEXANDRA S A | 2006 | Curr Opin Colloidln2006，11，4： | 1 |
| 4 | Nonbone Marrow-Derived Circulating Progenitor Ceils Contribute to Postnatal Neovascularization Following Tissue Ischemia 显示文摘 | Alexandra A Markus R Kenichiro S | 2007 | Cir Res2007，100，4： | 1 |
| 5 | Intluenee of lutein supplementation on macular pigment, assessed with two objective techniques显示文摘 | TOS T J BERENDSCHOT M ALEXANDRA GOLDBOHM R WILHELMINA A KLOPPING A | 2000 | Investigative Ophthalmology & Visual Science2000，41，11： | 1 |
| 6 | Lay- er-by-layer engineered capsules and their applications 显示文摘 | ANGUS P R J CHRISTINA C ALEXANDRA S A | 2006 | Curr Opin Colloid Interface Sci2006，11，4： | 1 |
| 7 | The science behind lutein显示文摘 | Alexandra A R | 2004 | Toxicology Letters2004，150，： | 1 |
| 8 | The science behind lutein显示文摘 | ] Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，1： | 1 |
| 9 | The science behind lutein显示文摘 | Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，： | 1 |
| 10 | Kinetic determination of trace amounts of Cu (Ⅱ) in water based on its catalytic effect on the reation of mercaptosuccinic acid and Cr (Ⅵ)显示文摘 | Alexandra A R loan S B Dana D M | 2002 | Mierochim Acta2002，140，： | 1 |
| 11 | Meta-Analysis of Risedronate for the Treatment of Postmenopausal Osteoporosis显示文摘 | Ann C Peter T Jonathan A Bruce W Nicole Z Alexandra P Vivian R Beverley S George W Gordon G | 2002 | Endocrine Reviews2002，23，4： | 1 |
| 12 | Height, weight,weight change, and ovarian cancer risk in the Netherlands cohort study on diet and cancer显示文摘 | Schouten L J Alexandra G R Brandt P A | 2003 | Am J Epidemiol2003，157，5： | 1 |
| 13 | The science behind lutein显示文摘 | Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，1： | 1 |
| 14 | The science behind lutein显示文摘 | Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，： | 1 |
| 15 | A Family of ductile intermetallic compounds 显示文摘 | Gschneidner Jr K A Alan R Alexandra P | 2003 | Nature Materials2003，2，： | 1 |
| 16 | The science behind lutein显示文摘 | Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，： | 1 |
| 17 | The science behind lutein显示文摘 | Alexandra A R Andrew S | 2004 | Toxicology Letters2004，150，： | 1 |
| 18 | Continuous analog of the Gauss-Newton method 显示文摘 | RUBEN G A ALEXANDER G R ALEXANDRA B S | 1999 | Mathematical Models and Methods in Applied Sciences1999，9，3： | 1 |
| 19 | Income-based Environmental Responsibility显示文摘 | Alexandra M Jo(a)o R Manfred L | | 0，，12： | 1 |
| 20 | Extraction of watersoluble hemicelluloses from barley husks显示文摘 | Alexandra A R Persson T Krawczyk H | 2009 | Bioresorce Technology2009，100，2： | 1 |
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