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| 1 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018，26，10： | 27 |
| 2 | Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma显示文摘Hepatobiliary cystadenomas (HBC) and cystadenocarci- nomas are rare cystic lesions. Most patients with these lesions are asymptomatic, but presentation with ob- structive jaundice may occur. The first patient presented with intermittent colicky pain and recurrent obstructive jaundice. Imaging studies revealed a polypoid lesion in the left hepatic duct. The second patient had recurrent jaundice and cholangitis. Endoscopic retrograde cholan- giopancreatography (ERCP) showed a cystic lesion at the confluence of the hepatic duct. In the third patient with intermittent jaundice and cholangitis, cholangioscopy re- vealed a papillomatous structure protruding into the left bile duct system. In the fourth patient with obstructive jaundice, CT-scan showed slight dilatation of the intrahe- patic bile ducts and dilatation of the common bile duct of 3 cm. ERCP showed filling of a cystic lesion. All patients underwent partial liver resection, revealing HBC in the specimen. In the fifth patient presenting with obstructive jaundice, ultrasound examination showed a hyperecho- genic cystic lesion centrally in the liver. The resection specimen revealed a hepatobiliary cystadenocarcinoma. HBC and cystadenocarcinoma may give rise to obstruc- tive jaundice. Evaluation with cross-sectional imaging techniques is useful. ERCP is a useful tool to differentiate extraductal from intraductal obstruction. | Deha Erdogan Olivier RC Busch Erik AJ Rauws Otto M van Delden Dirk J Gouma Thomas M van Gulik | 2006 | World Journal of Gastroenterology2006，12，35： | 26 |
| 3 | Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease显示文摘AIM: To evaluate the results of the treatment of simple liver cysts (solitary and multiple) and polycystic liver disease (PLD) using percutaneous sclerotherapy and/or surgical procedures in a single tertiary referral centre. METHODS: Retrospective analysis of 54 patients referred for evaluation and possible treatment of simple liver cysts (solitary and multiple) and PLD, from January 1997 to July 2006. RESULTS: Simple liver cysts were treated in 41 pts (76/) with a mean size of 12.6 cm. The most common reason for referral was abdominal pain or discomfort (85/). Percutaneous sclerotherapy was performed as initial treatment in 30 pts, showing cyst recurrence in 6 pts (20/). Surgical treatment was initially performed in 11 pts with cyst recurrence in 3 pts (27/). PLD was treated in 13 pts (24/) with a mean size of the dominant cyst of 13 cm. Percutaneous sclerotherapy for PLD was performed in 9 pts with recurrence in 7 pts (77.8/). Surgical treatment for PLD was undertaken in 4 pts (30.8/) with recurrence in all. Eventually, 2 pts with PLD in the presence of polycystic kidney disease underwent liver-and kidney transplantation because of deterioration of liver and kidney function. CONCLUSION: The majority of patients with simple liver cysts and PLD are referred for progressive abdominal pain. As initial treatment, percutaneous sclerotherapy is appropriate. Surgical deroofing is indicated in caseof cyst recurrence after percutaneous sclerotherapy. However, the results of percutaneous sclerotherapy and surgical treatment for PLD are disappointing. Partial liver resection is indicated when there is suspicion of a pre-malignant lesion. | Deha Erdogan Otto M van Delden Erik AJ Rauws Olivier RC Busch Johan S Lameris Dirk J Gouma Thomas M van Gulik | 2007 | World Journal of Gastroenterology2007，13，22： | 15 |
| 4 | 25-羟维生素D和甲状旁腺激素与高血压的相关性显示文摘有研究证实,维生素D缺乏和甲状旁腺激素(PTH)过高与高血压的发生密切相关。维生素D缺乏不仅可以影响肾素血管紧张素系统及PTH水平,而且可以直接参与血管炎性反应,影响高血压的发生发展。PTH可以通过促进血管炎性反应及血管钙化等参与高血压的进展。目前还没有前瞻性研究同时评估维生素D和PTH水平与高血压发病的关系。该研究分析多民族动脉粥样硬化研究的前瞻性数据,发现低水平25羟维生素D[25(OH)D]和高水平PTH与高血压发病相关,特别是在肥胖人群中。但在校正混杂因素后,25(OH)D水平与高血压发病的相关性无统计学意义,而PTH水平与高血压发病仍然相关。鉴于维生素D缺乏和PTH过量在人群中是普遍现象,该研究对于更好地了解高血压发病机制,在人群中开展高血压预防工作有重要意义。 | van Ballegooijen AJ Kestenbaum B Sachs MC de Boer IH Siscovick DS Hoofnagle AN Ix JH Visser M Brouwer IA 练桂丽 叶鹏 | 2014 | 中华高血压杂志2014，22，6： | 10 |
| 5 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 6 | 原发性低密度脂蛋白胆固醇≥4.94mmol/L的男性降低低密度脂蛋白胆固醇对心血管病的影响显示文摘原发性低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)≥4.94mmol/L(190mg/dL)的患者由于长期暴露在显著升高的LDL-C下,心血管动脉粥样硬化的风险更高。因此,对于这些患者通常建议采用他汀类药物治疗,但是缺少随机试验证据支持。在该研究中,研究者提供了一些降低LDL-C对心血管病影响的初级预防资料。 | Vallejo-Vaz AJ Robertson M Catapano AL Watts GF Kastelein JJ Packard CJ Ford I Ray KK 黄洁 叶鹏 | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 7 | Hip hemi-arthroplasty for neck of femur fracture:What is the current evidence?显示文摘This editorial reviews and summarises the current evidence(meta-analyses and Cochrane reviews) relating to the use of hip hemi-arthroplasty for neck of femur fractures. Regarding the optimal surgical approach,two recent meta-analyses have found that posterior approaches are associated with: higher rates of dislocation compared to lateral and anterior approaches; and higher rates of re-operation compared to lateral approaches. Posterior approaches should therefore be avoided when performing hip hemi-arthroplasty procedures. Assessing the optimal prosthesis head component,three recent meta-analyses and one Cochrane review have found that while unipolar hemiarthroplasty can be associated with increased rates of acetabular erosion at short-term follow-up(up to 1 year),there is no significant difference between the unipolar hemi-arthroplasty and bipolar hemi-arthroplasty for surgical outcome,complication profile,functional outcome and acetabular erosion rates at longer-term follow-up(2 to 4 years). With bipolar hemi-arthroplasty being the more expensive prosthesis,unipolar hemi-arthroplasty is the recommended option. With regards to the optimal femoral stem insertion technique,three recent metaanalyses and one Cochrane Review have found that,while cemented hip hemi-arthroplasties are associated with a longer operative time compared to uncemented Hip Hemi-arthroplasties,cemented prostheses have lower rates of implant-related complications(particularly peri-prosthetic femoral fracture) and improved postoperative outcome regarding residual thigh pain and mobility. With no significant difference found between the two techniques for medical complications and mortality,cemented hip hemi-arthroplasty would appear to be the superior technique. On the topic of wound closure,one recent meta-analysis has found that,while staples can result in a quicker closure time,there is no significant difference in post-operative infections rates or wound healing outcomes when comparing staples to sutures. Therefore,either suture or staple wound closure techniques appear equally appropriate for hip hemiarthroplasty procedures. | Greg AJ Robertson Alexander M Wood | 2018 | World Journal of Orthopedics2018，9，11： | 4 |
| 8 | Long-term follow-up of quality of life in high-risk patients undergoing transcatheter aortic valve implantation for symptomatic aortic valve stenosis显示文摘BackgroundTranscatheter 大动脉的阀门培植(TAVI ) 与严重征兆的大动脉的狭窄为病人成为了标准治疗(作为) 为外科的大动脉的阀门代替在很高的风险考虑了。这亚学习的目的是评估长期的(> 4 年) 在 octogenarians 的生活(QoL ) 的健康相关的质量经历了 TAVI.MethodsA 单个中心在在 TAVI 以后经历了框架分析评价 4 年的二十个病人的观察登记。健康相关的 QoL 被评估,用短 Form-36 ( SF-36 ),吗 EuroQoL-5D ( EQ-5D )和 questionnaires.ResultsThe 平均数 SF-36 subscale 在后续获得的视觉类似物分数(EQ管)是物理的工作 40.8 ????????????????????????????搠?潮潶???吗?湡楧灯慬瑳?????????愠杮潩牧灡票?€ 敦潭潲潰汰瑩慥???????????????愠桴牥'啼蠹溃浚? | Marjo JAG De Ronde-Tillmans Tom AJ de Jager Jeannette A Goudzwaard Nahid El Faquir Nicolas M van Mieghem Felix Zijlstra Elisabeth MWJ. Utens Francesco US Mattace-Raso MaRie J Lenzen Peter PT de Jaegere | 2018 | Journal of Geriatric Cardiology2018，15，4： | 3 |
| 9 | Slow transport rates of cyto-skeletal proteins change during regeneration of axotomized retinal neurons in adult rats显示文摘 | Mckerracher L Vidal-Ssanz M Aguayo AJ | 1990 | J Neurosci1990，10，2： | 2 |
| 10 | Observations on the astrocyte response to a cerebral stem wound in adoult rats显示文摘 | Mathewson AJ Berry M | 1985 | Brain Res1985，327，12： | 2 |
| 11 | 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)显示文摘 | Giuseppe Mancia Guy De Backer Anna Dominiczak Renata Cifkova Robert Fagard Giuseppe Germano Guido Grassi Anthony M Heagerty Sverre E Kjeldsen Stephane Laurent Krzysztof Narkiewicz Luis Ruilope Andrzej Rynkiewicz Roland E Schmieder Harry AJ Struijker Boudi | 2007 | Journal of Hypertension2007，，6： | 2 |
| 12 | Relative efficacy of acute relapse in MS显示文摘 | Thompson AJ ennard C wash M t al | | Neurology0，9，： | 2 |
| 13 | Simplifi ed criteria for the diagnosis of autoimmune hepatitis显示文摘 | Hennes EM Zeniya M Czaja AJ | | Hepatology0，，： | 2 |
| 14 | 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)显示文摘 | Giuseppe Mancia Guy De Backer Anna Dominiczak Renata Cifkova Robert Fagard Giuseppe Germano Guido Grassi Anthony M Heagerty Sverre E Kjeldsen Stephane Laurent Krzysztof Narkiewicz Luis Ruilope Andrzej Rynkiewicz Roland E Schmieder Harry AJ Struijker Boudi | 2007 | Journal of Hypertension2007，，6： | 2 |
| 15 | Role of MAP kinase pathways in mediating IL- 6 production in human primary mesangial and proximal tubular cells显示文摘 | Leonard M Ryan MP Watson AJ | 1999 | Kidney Int1999，56，4： | 2 |
| 16 | ln vivo recombineering of bacteriophage lambda by PCR fragments and single-strand oligonucleotides显示文摘 | Oppenheim AB Rattray AJ Bubunenko M | 2004 | Virology2004，319，2： | 1 |
| 17 | Role of DCSIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine显示文摘 | Hildesheim A Trivett M | 2006 | Eur J Immunol2006，36，2： | 1 |
| 18 | Cell migration and chimerism after whole-organ transplantation:the basis of graft acceptance显示文摘 | Starzl TE Demetris AJ Trucco M | 1993 | Hepatology1993，17，6： | 1 |
| 19 | Evidence of an association between Chlamydia psittaci and ocular adnexal lymphoma 显示文摘 | Ferreri AJ Guidoboni M Ponzoni M | 2004 | J Natl Cancer Inst2004，96，： | 1 |
| 20 | Prognosis and safety of anticoagu|ation in in- tracranial artery dissections in adults显示文摘 | Metso TM Metso AJ Helenius J Haapaniemi E Salonen O Porras M | 2007 | Stroke2007，38，6： | 1 |
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