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| 1 | Anti-arthritis activity of roots of Hemidesmus indicus R.Br.(Anantmul)in rats显示文摘Objective:To investigate the protective effects of hydroalcoholic and its fractions from roots of Hemidesmus indicus on arthritis in in vitro models of rodents.Methods:Preliminary phytochemical analysis and thin-layer chromoatography were performed to analyze constituents of hydroalcoholic extract and its three fraction namely ethyl acetate fraction,chloroform fraction and residual fraction of mot of Hemidesmus indicus.Arthritis rats models were established by Complete Freund’s Adjuvant.The parameters including paw edema,body weight,arthritic index,erythrocyte sedimentation rate,serum rheumatoid factor,serum C-reactive protein,serum nitrite level,and histopathology of synovial joints were observed.Methotrexate was taken as positive control.Results:Rats treated with hydroalcoholic extract(450 mg/kg,p.o.),ethyl acetate (75 mg/kg,p.o.),chloroform(60 mg/kg,p.o) and residual fractions(270 mg/kg,p.o.),showed significant decrease in physical and biochemical parameters compared with arthritic model rats. Hydroalcoholic extract and its ethyl acetate fraction of Hemidesmus indicus showed significantly higher anti-arthritic activity than chloroform and residual fraction.Histopathological analysis demonstrated that both of hydroalcoholic extract and its ethyl acetate fraction had comparable anti-arthritic activity with methotrexates.Conclusions:The present study suggests that Hemidesmus indicus has protective activity against arthritis and the activity might be attributed to presence of terpenoid in hydroalcoholic extract,as well as in ethyl acetate fraction. | Alka Mehta Neeraj K Sethiya Chetan Mehta GB Shah | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 4 |
| 2 | Dabska tumor ( Endovascular papillary angioendothelioma) of testis: a case report with brief review of literature 显示文摘 | Alka B Ritambra N Yashwant K | 2006 | Diagn Pathol2006，22，1： | 1 |
| 3 | Paclitaxel and its formulations显示文摘 | Anil K Singla Alka Garg Deepika Aggarwal | 2002 | Int J Pharm2002，235，17： | 1 |
| 4 | Assessment of genetic relationships in Mentha species显示文摘 | Khanuja S P S Shasany A K Srivastava Alka | 2000 | Euphytica2000，111，2： | 1 |
| 5 | Use of mirabegron in treating overactive bladder显示文摘 | Alka A B Ruwan F Vik K | 2012 | Int Urogynecol J2012，23，： | 1 |
| 6 | Toxic effects of lcachatc of water hyacinth decay on the growth of Scenedesmus obliquus (Chlorophyta) 显示文摘 | ALKA S MAHENDRA K G PRADEEP K S | 1996 | Water Research1996，30，10： | 1 |
| 7 | Nutritional values of some commercial edible bamboo species of the North Eastern Himalayan region显示文摘 | Bhatt B P Singh K Singh Alka | 2005 | India Journal of Bamboo and Rattan2005，4，2： | 1 |
| 8 | Emerging Trends in Research onSpatial and Temporal Organization of Terpenoid Indole AlkaloidPathway in Catharanthus roseus: A Literature Update 显示文摘 | Priyanka V Ajay K M Alka S | 2012 | Protoplasma2012，249，2： | 1 |
| 9 | Studies on slow release fertilizer: a method for evaluation fertilizers 显示文摘 | Sharon G M alka K A | 1990 | Soil Science1990，150，： | 1 |
| 10 | Novel multiplex PCR approaches for the simultaneous detection of human pathogens: Escherichia coli O157:H7 and Listeria monocytogenes 显示文摘 | Alka M Utpal K M | 2007 | Journal of Microbiological Methods2007，68，： | 1 |
| 11 | Assessment of genetic relationships in Mentha species显示文摘 | Khanuja S P S Shasany A K Alka Srivastava | | 0，，： | 1 |
| 12 | Effect of Vari- able Roughness on Runoff显示文摘 | Rai R K Upadhyay Alka Singh V P | 2010 | Journal of Hydrolo- gy2010，382，1： | 1 |
| 13 | Paelitaxel and its formulations显示文摘 | Anil K S Alka G Deepika A | 2002 | Int J Pharm2002，235，122： | 1 |
| 14 | The metabolic syndrome,inflammation,and risk of cognitive decline显示文摘 | Kristine Y Alka K Karla L | 2004 | JAMA2004，292，18： | 1 |
| 15 | Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases:a jour- ney revisited 显示文摘 | Yashwant K Alka B Ranjana W M | 2009 | Diagn Pathol2009，4，1： | 1 |
| 16 | Antinuclean antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited显示文摘 | YASHWANT K ALKA B RANIANA W M | 2009 | Diagnostic Pathol2009，4，1： | 1 |
| 17 | Study of indole acetic acid and antioxidant defense system of wheat grown under sewage water显示文摘 | Kumar Chandra Shekhar Singh Alka Sagar R K | 2012 | International Journal of Environmental Sciences2012，，2： | 1 |
| 18 | Removal of malachite green from aqueous solution using nano-iron oxide-loaded alginate micro- spheres:Batch and column studies 显示文摘 | Soni Anjali Tiwari Alka Bajpai A K | 2014 | Research on Chemical In- termediates2014，40，3： | 1 |
| 19 | Comparative studies on metabolites concentration patterns of in vitro and field-raised maize kernels from tip and middle ear positions显示文摘 | Malik C P Alka S Amarjeet K | 1998 | Phytomorphology1998，48，1： | 1 |
| 20 | Malignant transformation of Syrian Hamster Embryo(SHE) cells in primary culture by malachite green:Transformation is associated with abrogation of G2/M checkpoint control显示文摘 | RaoK V K Daisy M M Alka A R | 1998 | Cell Biology International1998，22，78： | 1 |
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