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| 1 | Routine diagnosis of intestinal tuberculosis and Crohn's disease in Southern India显示文摘AIM:To investigate whether routinely measured clinical variables could aid in differentiating intestinal tuberculosis(ITB)from Crohn’s disease(CD).METHODS:ITB and CD patients were prospectively included at four South Indian medical centres from October 2009 to July 2012.Routine investigations included case history,physical examination,blood biochemistry,ileocolonoscopy and histopathological examination of biopsies.Patients were followed-up after 2 and 6 mo of treatment.The diagnosis of ITB or CD was re-evaluated after 2 mo of antituberculous chemotherapy or immune suppressive therapy respectively,based on improvement in signs,symptoms and laboratory variables.This study was considered to be an exploratory analysis.Clinical,endoscopic and histopathological features recorded at the time of inclusion were subject to univariate analyses.Disease variables with sufficient number of recordings and P<0.05 were entered into logistic regression models,adjusted for known confounders.Finally,we calculated the odds ratios with respective confidence intervals for variables associated with either ITB or CD.RESULTS:This study included 38 ITB and 37 CD patients.Overall,ITB patients had the lowest body mass index(19.6 vs 22.7,P=0.01)and more commonly reported weight loss(73%vs 38%,P<0.01),watery diarrhoea(64%vs 33%,P=0.01)and rural domicile(58%vs 35%,P<0.05).Endoscopy typically showed mucosal nodularity(17/31 vs 2/37,P<0.01)and histopathology more frequently showed granulomas(10/30vs 2/35,P<0.01).The CD patients more frequently reported malaise(87%vs 64%,P=0.03),nausea(84%vs 56%,P=0.01),pain in the right lower abdominal quadrant on examination(90%vs 54%,P<0.01)and urban domicile(65%vs 42%,P<0.05).In CD,endoscopy typically showed involvement of multiple intestinal segments(27/37 vs 9/31,P<0.01).Using logistic regression analysis we found weight loss and nodularity of the mucosa were independently associated with ITB,with adjusted odds ratios of 8.6(95%CI:2.1-35.6)and 18.9(95%CI:3.5-102.8)respectively.Right lower abdominal quadrant pain on examination and involvement of≥3 intestinal segments were independently associated with CD with adjusted odds ratios of 10.1(95%CI:2.0-51.3)and 5.9(95%CI:1.7-20.6),respectively.CONCLUSION:Weight loss and mucosal nodularity were associated with ITB.Abdominal pain and excessive intestinal involvement were associated with CD.ITB and CD were equally common. | Geir Larsson Thrivikrama Shenoy Ramalingom Ramasubramanian Leena Kondarappassery Balakumaran Milada Cvancarova Smstuen Gunnar Aksel Bjune Bjφrn Allan Moum | 2014 | World Journal of Gastroenterology2014，20，17： | 5 |
| 2 | Probabilistic load flow considering dependence between input nodal powers显示文摘 | Leite D S Arienti V L Allan RN | 1984 | IEEE Transactions on Power Apparatus and Systems1984，103，6： | 1 |
| 3 | Long - term outcome of surgical management for diffuse jejunoileal Crohn's disease显示文摘 | Yamamoto T Allan RN Keighley MR | 2001 | Surgery2001，129，1： | 1 |
| 4 | Probabilistic power-flow techniques extended and applied to operational decision making显示文摘 | Allan RN GriggCH NeweyDA | 1976 | Proceedings of the Institution of Electrical Engineers1976，123，12： | 1 |
| 5 | Employment problems and pro- spects for Patients with inflammatory bowel disease显示文摘 | WykeR J Edwards FC Allan RN | 1998 | Gut1998，29，9： | 1 |
| 6 | Risk factors for intra-abdominal sepsis after surgery in Crohn’s disease显示文摘 | Yamamoto T Allan RN Keighley MR | 2000 | Dis Colon Rectum2000，43，8： | 1 |
| 7 | Local Recurrence After Laparoscopic Radiofrequency Thermal Ablation of Hepatic Tumors显示文摘 | Allan Siperstein MD Adella Garland MD Kristen Engle MD Stanley Rogers MD Eren Berber MD Arash Foroutani MD Andreas String MD Tamara Ryan RN Philip Ituarte PhD MPH | 2000 | Annals of Surgical Oncology2000，，2： | 1 |
| 8 | Colorectal cancer in ulcerative colitis:a cohort study of primay referrals from three centres显示文摘 | Gldy SN Prior P Allan RN | 1988 | Gut1988，29，： | 1 |
| 9 | Prevalence and characteristics of individuals with chronic kidney disease in a large health maintenance organization显示文摘 | Allen RN Brian JG Allan JC | 2001 | Am J Kidney Dis2001，37，： | 1 |
| 10 | Risk factors for intra-abdominal sepsis after surgery in Crohn's disease 显示文摘 | Yamamoto T Allan RN Keighley MR | 2000 | Dis Colon Rectum2000，43，8： | 1 |
| 11 | A reliability test system for education purposes-basic distribution system data and results显示文摘 | Allan RN Billinton R Sjarief I | 1991 | IEEE Transaction on Power Systems1991，6，2： | 1 |
| 12 | Crohn disease patients who quit smoking have a reduced risk of reoperation and recurrence 显示文摘 | Ryan WR Allan RN Yamamoto T | 2004 | Am J Surg2004，187，2： | 1 |
| 13 | Enzymatic and mor- phometric evidence for Crohn's diseaseas a diffuse le- sion of the gastrointestinal tract显示文摘 | Dunne WT Cooke WT Allan RN | 1977 | Gut1977，18，29： | 1 |
| 14 | Effect of fecal diversion alone on perianal Crohn's disease 显示文摘 | Yamamoto T Allan RN Keighley MRB | 2000 | World J Surg2000，24，10： | 1 |
| 15 | Probabilistic techniques inAC load flow analysis显示文摘 | Allan RN Al-shakarchi M R G | 1977 | Proceedings of the Institution of Electrical Engineers1977，124，2： | 1 |
| 16 | Risk factors for intra- abdominal sepsis after surgery in Crohn's disease显示文摘 | Yamamoto T Allan RN Keighley MR | 2000 | Dis Colon Rectum2000，43，8： | 1 |
| 17 | Areliability test system for education purposes : basic distribution system data and results显示文摘 | Allan RN Billinton R SjariefI | 1991 | IEEETrans onPower Systems1991，6，2： | 1 |
| 18 | Crohn disease patients who quit smoking have a reduced risk of reoperation and recurrence显示文摘 | Ryan WR Allan RN Yamamoto T | 2004 | Am JSung2004，187，2： | 1 |
| 19 | Stage at diagnosis and colorectal cancer survival in six high-income countries: A population-based study of patients diagnosed during 2000–2007显示文摘 | Camille Maringe Sarah Walters Bernard Rachet John Butler Tony Fields Paul Finan Roy Maxwell Bj?rn Nedreb? Lars P?hlman Annika Sj?vall Allan Spigelman Gerda Engholm Anna Gavin Marianne L. Gjerstorff Juanita Hatcher Tom B. Johannesen Eva Morris Colleen E. M | 2013 | Acta Oncologica2013，，5： | 1 |
| 20 | Serum Adiponectin Is a Predictor of Coronary Heart Disease: A Population-Based 10-Year Follow-Up Study in Elderly Men显示文摘 | Jan Frystyk Christian Berne Lars Berglund Karin Jensevik Allan Flyvbjerg Bj?rn Zethelius | 2007 | The Journal of Clinical Endocrinology & Metabolism2007，，2： | 1 |
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