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1篇 您的检索式:作者名="Amanda C.Y.Chan"
    题名 作者 年代 出处 被引量
1CD137L,a driver of harmful inflammation in the nervous system显示文摘CD137 (TNFRSF9,4-1BB) is a member of the tumor necrosis factor (TNF) receptor family and a potent costimulatory molecule.High levels of CD137 are expressed on T cells upon activation.CD137 signaling in T cells,either by cognate interaction with antigen-presenting cells (APC)or by agonistic anti-CD137 antibodies,strongly enhances proliferation,interferon-y secretion,and cytolytic activity of T cells.Thus,CD137 signaling is a main driver of cellular,type 1 helper T cells (Th1)and type 1 cytolytic T cells (Tc1) polarised immune responses.Hiu Yi Wong Amanda C.Y.Chan Anselm Mak Herbert Schwarz 2023Neural Regeneration Research2023,18,11:0
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