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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat显示文摘 | Jan Schmidt Kent Lewandrowsi Andrew L. Warshaw Carolyn C. Compton David W. Rattner | 1992 | International Journal of Pancreatology1992，，1： | 1 |
| 3 | Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat显示文摘 | Jan Schmidt Kent Lewandrowsi Andrew L. Warshaw Carolyn C. Compton David W. Rattner | 1992 | International Journal of Pancreatology1992，，1： | 1 |
| 4 | Nomenclature for members of the expansin superfamily of genes and proteins显示文摘 | Hans Kende Kent Bradford David Brummell Hyung-taeg Cho Daniel Cosgrove Andrew Fleming Chris Gehring Yi Lee Simon Mcqueen-mason Jocelyn Rose Laurentius Voesenek | 2004 | Plant Molecular Biology2004，，3： | 1 |
| 5 | A model of clin- ical problem-based learning for clinical attachments in medicine显示文摘 | Derek C Macallan Andrew Kent Sandra C Holmes | 2009 | Medi- cal Education2009，，43： | 1 |
| 6 | Diffusion-weighted MR Imaging for Determination of Hepatocellular Carcinoma Response to Yttrium-90 Radioembolization显示文摘 | Jie Deng Frank H. Miller Thomas K. Rhee Kent T. Sato Mary F. Mulcahy Laura M. Kulik Riad Salem Reed A. Omary Andrew C. Larson | 2006 | Journal of Vascular and Interventional Radiology2006，，7： | 1 |
| 7 | A model ofclinical problem - based learning for clinical attachments in medicine显示文摘 | Derek C Macallan Andrew Kent Sandra C Holmes | 2009 | MEDICAL EDUCATION2009，43，： | 1 |
| 8 | Clinical adjusting to disfigurement: processes involved in dealing with being visibly different 显示文摘 | Andrew Thompson Gerry Kent | 2001 | Psychology Review2001，21，7： | 1 |
| 9 | A model of clinical problem-based learning for clinical attachments in medicine显示文摘 | Derek C Macallan Andrew Kent Sandra C Holmes | | 0，，08： | 1 |
| 10 | Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat显示文摘 | Jan Schmidt Kent Lewandrowsi Andrew L. Warshaw Carolyn C. Compton David W. Rattner | 1992 | International Journal of Pancreatology1992，，1： | 1 |
| 11 | Morphometric characteristics and homogeneity of a new model of acute pancreatitis in the rat显示文摘 | Jan Schmidt Kent Lewandrowsi Andrew L. Warshaw Carolyn C. Compton David W. Rattner | 1992 | International Journal of Pancreatology1992，，1： | 1 |
| 12 | A model of clinical problem-based learning for clinical attachments in medicine显示文摘 | Derek C Macallan Andrew Kent Sandra C Holmes etal | 2009 | MEDICAL EDUCATION2009，43，： | 1 |
| 13 | A model of clinical problem- based learning for clinical attachments in medicine显示文摘 | Derek C Macallan Andrew Kent Sandra C Holmes | 2009 | Medical Education2009，43，8： | 1 |
| 14 | Retained Foreign Bodies After Surgery显示文摘 | Amy E. Lincourt Andrew Harrell Joseph Cristiano Cathy Sechrist Kent Kercher B. Todd Heniford | 2007 | Journal of Surgical Research2007，，2： | 1 |
| 15 | Vertebral Endplate Fractures: An Indicator of the Abnormal Forces Generated in the Spine After Vertebroplasty显示文摘 | Andrew TTrout David FKallmes Kennith FLayton Kent RThielen Joseph GHentz | 2009 | J Bone Miner Res2009，，11： | 1 |
| 16 | A male - specific role for SOX9 in vertebrate sex determination 显示文摘 | Kent J Wheafley S C Andrews J E | 1996 | Develop- ment1996，122，9： | 1 |
| 17 | Predictability of US tornado outbreak seasons using ENSO and northern hemisphere geopotential height variability显示文摘The predictability of dangerous atmospheric phenomena such as tornado outbreaks has generally been limited to a week or less. However, recent work has demonstrated the importance of the Rossby wavetrain phasing over the United States in establishing outbreak-favorable environments. The predictability of Rossby wavetrain phasing is strongly related to numerous climate-scale interannual variability indices, which are predictable many months in advance. To formalize the relationship between interannual variability indices and seasonal tornado outbreak frequency, indices derived from monthly mean Northern Hemisphere 500-hPa and 1000-hPa geopotential height fields and Ni?o 3.4 indices for ENSO phase were compared to annual tornado outbreak seasonal frequencies. Statistical models predicting seasonal outbreak frequency were established using linear(stepwise multivariate linear regressione SMLR) and nonlinear(support vector regressione SVR) statistical modeling techniques.The stepwise methodology revealed predictors that are important in establishing outbreak-favorable environments at long lead times. Additionally, the results of the statistical modeling revealed that the nonlinear SVR technique reduced root mean square errors produced by the control SMLR technique by 28% and provided more consistent forecasts. A preliminary physical analysis revealed that years with high outbreak frequencies were associated with the presence of 500-mb troughs over the central and western US during the peak of outbreak season, while lower frequencies were consistent with ridging over the US or northwest flow over the Plains. These patterns support the results of the statistical modeling, which demonstrate the utility of geopotential height variability as a predictability measure of outbreak frequency. | Kent H.Sparrow Andrew E.Mercer | 2016 | Geoscience Frontiers2016，7，1： | 1 |
| 18 | Less invasive posterior fixation method following transforaminal lumbar interbody fusion: a biomechanical analysis显示文摘 | Andrew V. Slucky Darrel S. Brodke Kent N. Bachus John A. Droge John T. Braun | 2006 | The Spine Journal2006，，1： | 1 |
| 19 | A Better Model of Acute Pancreatitis for Evaluating Therapy显示文摘 | JAN SCHMIDT DAVID W. RATTNER KENT LEWANDROWSKI CAROLYN C. COMPTON UMA MANDAVILLI WOLFRAM T. KNOEFEL ANDREW L. WARSHAW | 1992 | Annals of Surgery1992，，1： | 1 |
| 20 | Correlates of coronary blood flow before and after percutaneous coronary intervention and their relationship to angiographic and clinical outcomes in the RESTORE trial显示文摘 | C.Michael Gibson M.Imran Dotani Sabina A. Murphy Susan J. Marble Kent W. Dauterman Andrew D. Michaels J.Theodore Dodge | 2002 | American Heart Journal2002，，1： | 1 |
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