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| 1 | The role of chemosensory protein 10 in the detection of behaviorally active compounds in brown planthopper, Nilaparvata lugens显示文摘Chemosensory proteins(CSPs)play important roles in insects’chemoreception,although their specific functional roles have not been fully elucidated.In this study,we conducted the developmental expression patterns and competitive binding assay as well as knock‐down assay by RNA interference both in vitro and in vivo to reveal the function of NlugCSP10 from the brown planthopper(BPH),Nilaparvata lugens(Stål),a major pest in rice plants.The results showed that NlugCSP10 messenger RNA was significantly higher in males than in females and correlated to gender,development and wing forms.The fluorescence binding assays revealed that NlugCSP10 exhibited the highest binding affinity with cis‐3‐hexenyl acetate,eicosane,and(+)‐β‐pinene.Behavioral assay revealed that eicosane displayed attractant activity,while cis‐3‐hexenyl acetate,similar to(+)‐β‐pinene significantly repelled N.lugens adults.Silencing of NlugCSP10,which is responsible for cis‐3‐hexenyl acetate binding,significantly disrupted cis‐3‐hexenyl acetate communication.Overall,findings of the present study showed that NlugCSP10 could selectively interrelate with numerous volatiles emitted from host plants and these ligands could be designated to develop slow‐release mediators that attract/repel N.lugens and subsequently improve the exploration of plans to control this insect pest. | Muhammad Irfan Waris Aneela Younas Muhammad Muzammal Adeel Shuang-Gang Duan Sundas Rana Quershi Rana Muhammad Kaleem Ullah Man-Qun Wang | 2020 | Insect Science2020，27，3： | 9 |
| 2 | The importance of visualization of appendix on abdominal ultrasound for the diagnosis of appendicitis in children: A quality assessment review显示文摘BACKGROUND:Ultrasound has the first line investigation role in the diagnosis of acute appendicitis in children.The purpose of this study was to perform a quality assessment review on the visualization rate of appendix on ultrasound in children in the community hospital setting.METHODS:A retrospective chart review of the abdominal ultrasound findings for the visualization of the appendix was performed on paediatric patients ranging from 5 to 18 years.Data were collected from the two community hospitals of Toronto by using hospital electronic medical record for the ultrasound findings in patients presented with abdominal pain.RESULTS:Data from two community hospitals indicated visualization rate of the appendix as 11.0%and 23.2%for site 1 and site 2 respectively.In cases where the ultrasound was repeated the visualization rate remains the same.A two-proportion z-test was performed to find whether the visualization of appendix increases the likelihood of diagnosing appendicitis.The results revealed that the visualization of an appendix(P=0.52),significantly improved the diagnosis of appendicitis(z=34,P<0.001).CONCLUSION:Visualization of an appendix on ultrasound increases the likelihood of correctly diagnosing appendicitis.In our study,we found low visualization rate of appendix on ultrasound that could be the result of many factors that contribute towards the low visualization rate of an appendix on ultrasound.Hence,the challenges in identifying appendix should be minimized to improve the visualization and diagnosis of appendicitis on ultrasound. | Muhammad Akhter Hamid Ruqiya Afroz Uqba Nawaz Ahmed Aneela Bawani Dilnasheen Khan Rabia Shahab Asim Salim | 2020 | World Journal of Emergency Medicine2020，11，3： | 2 |
| 3 | Symptomatic pneumatosis intestinalis(including portal venous gas) after laparoscopic total colectomy显示文摘The development of intramural intestinal gas may indi-cate a serious postoperative complication and thereforeany radiological indication of such 'pneumatosis intes-tinalis'(PI) in an unwell patient after surgery shouldput the clinical team on high-alert. However immedi-ate recourse to relook laparotomy may not be alwaysnecessary and, further, in some cases may possiblyaccelerate the deterioration especially if it proves to benon-therapeutic. Careful and close clinical monitoring,as is described in this clinical report, may allow discrimi-native identification of those in whom this finding is infact transient and therefore benign and who thereforecan be successfully treated without operative re-inter-vention. We describe the presenting features and back-ground scenario of PI early after laparoscopic total col-ectomy for medically refractory, severe ulcerative colitisand detail the critical postoperative decision pivots. | Aneela Shah Hazar Al Furajii Ronan A Cahill | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，11： | 1 |
| 4 | Differential evolution based computation intelligence solver for elliptic partial differential equations显示文摘A differential evolution based methodology is introduced for the solution of elliptic partial differential equations (PDEs) with Dirichlet and/or Neumann boundary conditions. The solutions evolve over bounded domains throughout the interior nodes by minimization of nodal deviations among the population. The elliptic PDEs are replaced by the corresponding system of finite difference approximation, yielding an expression for nodal residues. The global residue is declared as the root-mean-square value of the nodal residues and taken as the cost function. The standard differential evolution is then used for the solution of elliptic PDEs by conversion to a minimization problem of the global residue. A set of benchmark problems consisting of both linear and nonlinear elliptic PDEs has been considered for validation, proving the effectiveness of the proposed algorithm. To demonstrate its robustness, sensitivity analysis has been carried out for various differential evolution operators and parameters. Comparison of the differential evolution based computed nodal values with the corresponding data obtained using the exact analytical expressions shows the accuracy and convergence of the proposed methodology. | Muhammad Faisal FATEH Aneela ZAMEER Sikander MMIRZA Nasir MMIRZA Muhammad Saeed ASLAM Muhammad Asif Zahoor RAJA | 2019 | Frontiers of Information Technology & Electronic Engineering2019，20，10： | 1 |
| 5 | Appraisal of MsepCSP14 for chemosensory functions in Mythimna separata显示文摘Chemosensory proteins (CSPs) have great contributions in performing diverse functions in insects. However, physiological appraisal of chemosensory protein genes still remains elusive in insects. We studied expression patterns and binding affinities of MsepCSP14, a chemosensory protein, in Mythimna separata. The distinct functions of MsepCSP14 were validated by employing different molecular techniques. The MsepCSP14 had high resemblance of sequence with chemosensory proteins of other insect family members. The MsepCSP14 expression was higher in antennal tissues of females than other tissues. Fluorescence binding assay validated that binding of nine out of 21 ligands to MsepCSP14 was higher at pH 7.4 than at pH 5.0. Three dimensional modeling (3D) and docking analysis predicted that amino acid residues of MsepCSP14 were involved in binding of compounds, and behavior assay displayed that adults of M. separata considerably responded to four volatiles from compounds demonstrating strong binding ability to MsepCSP14. Results of the present study suggest that MsepCSP14 is likely to mediate chemosensory functions in M. separata. | Aneela Younas Muhammad Irfan Waris Muhammad Shaaban Muhammad Tahir ul Qamar Man-Qun Wang | 2022 | Insect Science2022，29，1： | 1 |
| 6 | 2D Carbon Fiber Reinforced High Density Polyethylene Multi-Layered Laminated Composite Panels:Structural,Mechanical,Thermal,and Morphological Profile显示文摘Carbon fiber reinforced high density polyethylene multi-layered laminated composite panels(HDPE/CF MLCP) with excellent in-plane properties along transverse direction have been formulated. Composite architectures with carbon fiber(CF) designed in 2D layout in conventional composites can alleviate their properties in thickness direction, but all attempts so far developed have achieved restrained success. Here,we have exposed an approach to the high strength composite challenge, without altering the 2D stack design on the basis of concept of fiber reinforced laminated composites that would provide enhanced mechanical and thermal properties along transverse direction. CF sheets allowed the buckling of adjoining plies in 2D MLCP. We fabricated 2D MLCP by stacking the alternative CF and HDPE layers under different loading conditions, which resulted in high strength composites. These plies of CF and HDPE served as unit cells for MLCP, with CF offering much-needed fracture toughness and hardness to these materials.For 2D HDPE/CF MLCP, we demonstrated noteworthy improvement in physical and chemical interaction between CF and HDPE, in-plane fracture strain, flexural strength(30.684 MPa), bending modulus(7436.254 MPa), thermal stability(40.94%), and surface morphology, upon increasing the CF layers up to twenty, enabling these composites truly for high temperature and high strength applications. | Shahzad Maqsood Khan Nafisa Gull Muhammad Azeem Munawar Atif Islam Saba Zia Muhammad Shafiq Aneela Sabir Syed Muhammad Awais Muhammad Arif Butt Muhammad Taqi Zahid Butt Tahir Jamil | 2016 | Journal of Materials Science & Technology2016，32，10： | 1 |
| 7 | Hepatitis E virus superinfection in patients with chronic liver disease显示文摘 | Saeed S. Hamid Muslim Atiq Farooq Shehzad Aneela Yasmeen Tayyabun Nissa Abdul Salam Anwar Siddiqui Wasim Jafri | 2002 | Hepatology2002，，2： | 1 |
| 8 | Perinatal Outcome in Pregnancies Complicated by Isolated Oligohydramnios at term 显示文摘 | Aneela Umber | 2009 | Annals of King Edward Medical University2009，15，1： | 1 |
| 9 | Neuropsyehological perfomance and noradrenaline function in chronic fatigue syndrome under conditions of high arousal 显示文摘 | TMorriss K Robson M Aneela N | 2002 | Psychopharmacology( Berl)2002，163，2： | 1 |
| 10 | Perceived brand globalness in emerging markets and the moderating role of consumer ethnocentrism显示文摘 | Aneela Akram Dwight Merunka Muhammad Shakaib Akram | 2011 | International Journal of Emerging Markets2011，，4： | 1 |
| 11 | Gunshot injury to spine:An institutional experience of management and complications from a developing country显示文摘Purpose Gunshot wounds are the second leading cause of spinal cord injuries.Surgical intervention for gunshot injury to the spine carries a high rate of complications.There is a scarcity of data on civilian gunshot injuries to the spine in Pakistan.Approximately 60 cases over the last 10 years have been recoded,with unusual presentation and neurological recovery.Thus it is imperative to fill this gap in data,by reviewing cases of civilian gunshot injuries to spine presenting at a tertiary care hospital(Aga Khan University Hospital,Karachi).Methods This is a retrospective cohort study.Patients of all ages who presented to the emergency department of Aga Khan University Hospital,with gunshot injuries to spine between January 2005 and December 2016 were included in the study.Data were collected on neurological status(American Spinal Injury Association score was used for the initial and follow-up neurological assessment),extent of cord transection,motor and sensory deficits.The patients were further grouped into those with cord transection,and those with fractures of the bony spine but an intact spinal cord.These patients were then followed and the outcomes were recorded.Results A total of 40 patients were identified.The mean±SD of patients age was(30.9±9.5)years.Of the 40 patients with gunshot wounds,31 had the medical imaging performed at the facility,and hence they were included in this categorization.The remaining 9 patients were excluded from this additional grouping.Thirteen patients were managed surgically and 27 patients underwent the conservative management.The mean±SD of follow-up was(8.7±7.2)months.In our study,the thoracic spine was the most commonly injured region in gunshot injuries.Of the 31 patients with medical imaging performed at our institute,17(54.8%)had cord transection,of whom 8(47%)ultimately developed paraplegia.Conclusion The prognosis of gunshot injuries to the spine can be varied depending on whether the spinal cord is intact or transected.This will help healthcare providers to plan the further management of the patient and counsel them accordingly. | Mir Ibrahim Sajid Bushra Ahmad Shaikh Danish Mahmood Aneela Darbar | 2020 | Chinese Journal of Traumatology2020，23，6： | 1 |
| 12 | Inclusive Aspects of Urban Design:Sociability,Walkability and Overall Ambiance显示文摘Urban design is a multifaceted process that interfaces various aspects, extending from community physical activity and health improvement to social and environmental fields. An efficient urban design requires understanding of ideas, paradigms, and research from many dimensions of knowledge, i.e. anthropology, sociology, engineering, architecture, and urban planning. The debate in this paper is based on the fact that the sociability of a society is dependent on its urban design prototype. A systemic urban design increases the opportunity for walkability, sequentially enhancing the probability of real-time social interaction. Such an urban ambiance plays a significant role in human physical and mental well-being and their behaviors. The aspects of urban space, such as sociability, walkability and overall ambiance, are appraised according to the published literature. This paper aims at collecting the already proven specifics in one piece of writing to open up avenues for further research and establish the inclusive aspects of urban design.The literature from the final decade of the 20th century to contemporary works has been considered for this instance. The research concludes that interdisciplinary engagement and participation of the public in decision-making for urban design are necessary. It recommends further exploration of the relationship of sociability, walkability and urban ambiance, and their correlation with human well-being. | Aneela YASEEN | 2017 | Chinese Journal of Urban and Environmental Studies2017，5，1： | 0 |
| 13 | The Effects of Spherical Surface and Laser Polarization on the Photodetachment Cross Section of H^-显示文摘We report the combined effects of laser polarization and curvature of the spherical surface on the detached electron spectra from H-.The Theoretical imaging method is used as a tool of investigation.The photodetachment cross sections for various polarization angles,radii of curvatures and inter ion surface distances are displayed.The analysis of the spectra reveals that the laser polarization angle θL,curvature of the surface rc and inter ion surface distance d strongly affect oscillations in the spectra.Therefore,a fine control on the laser polarization and that of curvature in the surface can be used to control oscillations in the photodetachment of negative ions. | Muhammad Haneef Suneela Arif Jehan Akbar Nasrullah Shah Muhammad Zahir Aneela Shamim Hameed Ullah | 2013 | Communications in Theoretical Physics2013，59，3： | 0 |
| 14 | Utility of convalescent plasma for addressing the COVID-19 infection: brief review and case reports显示文摘Novel coronavirus,SARS-CoV-2 is responsible for causing a pandemic that has affected individuals worldwide,over 192 million people and about 4.1 million people died so far.The spread is ongoing and the numbers are still increasing.Numerous therapeutic approaches have been explored and developed during this pandemic.Immunotherapy with virus-specific antibodies in convalescent plasma(CP)has shown potential benefits for various pathogenic diseases.In many instances,it is the only available and safe management option for the COVID-19 patients.Here we describe two confirmed cases of COVID-19 from two different geographical areas that were managed with standard treatment modalities initially.Both of the patients were presented with high-grade fever,dry cough,and sore throat.Lab reports showed increased values of D-dimer,serum ferritin,leukocyte count(LC),Lactate dehydrogenase(LDH),and C-reactive protein(CRP).Chest X-ray showed bilateral infiltration(multifocal and bilateral ground-glass opacities and consolidations with peripheral and basal predominance),consistent with the previous reports on COVID-19 infection.The patients received conservative treatment according to the hospital's protocol.The convalescent plasma(from recovered patients)infusion was the last treatment given to both patients.After the convalescent plasma transfusion,both patients showed a reduction of viral load,an increase of anti-SARS-CoV-2 IgG and IgM antibodies,reduction in lung infiltration,with no adverse events.However,further randomized controlled trials are needed to investigate the full scope of safety and efficacy(both short and long-term)of convalescent plasma therapy for COVID-19 and other related infections. | Fazli Azim Md Shahidul Islam Ashraful Hoque Muhammad Javed Aneela Hayat Kaniz Fatema Molla Amiruzzaman Md.Nasir Uddin Kajal Kumar Karmakar Syed A.A.Rizvi | 2022 | Life Research2022，5，1： | 0 |
| 15 | Fuel loading pattern optimization of a pressurized water reactor by varying internal weights-based particle swarm optimization显示文摘Fuel reload pattern optimization is essential for attaining maximum fuel burnup for minimization of generation cost while minimizing power peaking factor(PPF).The aim of this work is to carry out detailed assessment of particle swarm optimization(PSO) in the context of fuel reload pattern search. With astronomically large number of possible loading patterns, the main constraints are limiting local power peaking factor, fixed number of assemblies,fixed fuel enrichment, and burnable poison rods. In this work, initial loading pattern of fixed batches of fuel assemblies is optimized by using particle swarm optimization technique employing novel feature of varying inertial weights with the objective function to obtain both flat power profile and cycle k_(eff)>1. For neutronics calculation, PSU-LEOPARD-generated assembly depletiondependent group-constant-based ADD files are used. The assembly data description file generated by PSU-LEOPARD is used as input cross-section library to MCRAC code, which computes normalized power profile of all fuel assemblies of PWR nuclear reactor core. The standard PSO with varying inertial weights is then employed to avoid trapping in local minima. A series of experiments havebeen conducted to obtain near-optimal converged fuelloading pattern of 300 MWe PWR Chashma reactor. The optimized loading pattern is found in good agreement with results found in literature. Hybrid scheme of PSO with simulated annealing has also been implemented and resulted in faster convergence. | Aneela Zameer Sikander M.Mirza Asifullah Khan Furqan Mir | 2018 | Nuclear Science and Techniques2018，29，3： | 0 |
| 16 | Prediction of promiscuous T-cell epitopes in the Zika virus polyprotein:An in silico approach显示文摘Objective:To predict immunogenic promiscuous T-cell epitopes from the polyprotein of the Zika virus using a range of bioinformatics tools.To date,no epitope data are available for the Zika virus in the IEDB database.Methods:We retrieved nearly 54 full length polyprotein sequences of the Zika virus from the NCBI database belonging to different outbreaks.A consensus sequence was then used to predict the promiscuous T cell epitopes that bind MHC 1 and MHC II alleles using Propred1 and Propred immunoinformatic algorithms respectively.The antigencity predicted score was also calculated for each predicted epitope using the Vaxi Jen 2.0 tool.Results:By using Pro Pred1,23 antigenic epitopes for HLA class I and 48 antigenic epitopes for HLA class II were predicted from the consensus polyprotein sequence of Zika virus.The greatest number of MHC class I binding epitopes were projected within the NS5(21%),followed by Envelope(17%).For MHC class II,greatest number of predicted epitopes were in NS5(19%) followed by the Envelope,NS1 and NS2(17% each).A variety of epitopes with good binding affinity,promiscuity and antigenicity were predicted for both the HLA classes.Conclusion:The predicted conserved promiscuous T-cell epitopes examined in this study were reported for the first time and will contribute to the imminent design of Zika virus vaccine candidates,which will be able to induce a broad range of immune responses in a heterogeneous HLA population.However,our results can be verified and employed in future efficacious vaccine formulations only after successful experimental studies. | Hamza Dar Tahreem Zaheer Muhammad Talha Rehman Amjad Ali Aneela Javed Gohar Ayub Khan Mustafeez Mujtaba Babar Yasir Waheed | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，9： | 0 |
| 17 | Beyond the Ontology of“Dance” as an Art: An Anthropological Analysis of Female Stage Performers显示文摘 | Aneela Sultana Waheed Chaudhry Amna Mushtaq | 2013 | History Research2013，3，1： | 0 |
| 18 | Antimicrobial activities of methanolic extract of Carissa opaca roots and its fractions and compounds isolated from the most active ethyl acetate fraction显示文摘Objective: To study the antibacterial and antifungal activities of methanolic extract of roots of Carissa opaca and its fractions in hexane, chloroform, ethyl acetate, n-butanol and water, and the isolated compounds.Methods: The zones of inhibition of the samples against test microorganisms were determined by agar well diffusion method. Minimum inhibitory concentrations of the samples were determined by agar well dilution method. Test microorganisms included four standard bacteria [Bacillus subtilis ATCC 6633(B. subtilis), Escherichia coli ATCC 8739(E. coli), Pseudomonas aeruginosa ATCC 9027(P. aeruginosa), and Staphylococcus aureus ATCC 6538], two standard fungi [Candida albicans ATCC 10231(C. albicans)] and Aspergillus niger, and six clinical isolates(B. subtilis, E. coli, P. aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterobacter cloacae). The most active fraction was investigated to isolate compounds. The chemical compounds isolated from the ethyl acetate fraction were identified by gas chromatography-mass spectrometer, high performance liquid chromatography and liquid chromatography-mass spectrometer.Results: E. coli, P. aeruginosa, and C. albicans were the most susceptible. Less polar fractions exhibited stronger efficacy than polar ones, and ethyl acetate fraction proved to be the most potent. Zones of inhibition of hexane, chloroform and ethyl acetate fractions, and amoxil against C. albicans were 19.96, 22.01, 23.10 and 19.20 mm, respectively. Ethyl acetate faction was the most toxic to all the test microorganisms, with minimum inhibitory concentrations of 8.0, 7.8 and 7.78 μg/m L against P. aeruginosa, C. albicans and B. subtilis, respectively. Isolated compounds, limonene, 2'-hydroxyacetophenone, vanillin, naphthalenone, 2,3,3-trimethyl-2-(3-methylbuta-1,3-dienyl)-6-methylenecyclohexanone, 2-benzenedicarboxylic acid, mono(2-ethylhexyl) ester, β-sitosterol, vitamin E, rutin, quercetin, lupeol, epigallocatechin, showed considerable antimicrobial activities against test microorganisms.Conclusions: The roots of Carissa opaca contain compounds with significant antimicrobial potential. | Dildar Ahmed Ramsha Saeed Nasir Shakeel Khaizran Fatima Aneela Arshad | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，7： | 0 |
| 19 | Metal-Doped Brushite Cement for Bone Regeneration显示文摘For the past several years,calcium phosphate cement was used in the biomedical applications.Outstanding biocompatibility,good bioactivity,self-setting qualities,minimum setting degree,appropriate toughness,and simple shape to accommodate any difficult geometry are among their most notable attributes.Calcium phosphate has some types and brushite is one of the most attractive mineral for bone repair application.Brushite is extensively employed in filling fractures and trauma treatments as a bone substituted material.This kind of material can potentially be used as a medicine delivery device.The replacement of metal,such as magnesium,zinc,and strontium ions,into the calcium phosphate structure is a major research topic these days.Brushite cement has low mechanical strength and quick setting rate.It is possible to produce biomaterials with higher mechanical characteristics.By adding metal that are great potential in controlling cellular density when included into biomaterials.As a result,it is a successful method to develop quite well regenerative medicine.This paper provides a detailed summary of the present achievements of metal-doped brushite cement for bone repair and healing process.The major purpose of this work is to give a simple but thorough analysis of current successes in brushite cement doped with Zn,Mg,Sr,and other ions as well as to highlight new advancements and prospects.The impact of metal replacement on cement physical and chemical properties,including microstructure,setting time,injectability,mechanical property,and ion release,is explored.The metal-doped cement has osteogenesis,angiogenesis,and antibacterial properties,as well as their prospective utility as drug carriers,also considered. | Muhammad Aqib Aneela Anwar Humayun Ajaz Samina Akbar Ahsan Manzoor Maham Abid Zohaib Waheed Qudsia Kanwal | 2023 | Journal of Bionic Engineering2023，20，6： | 0 |
| 20 | A Framework for e-Voting System Based on Blockchain and Distributed Ledger Technologies显示文摘Election allows the voter of a country to select the most suitable group of candidates to run the government.Election in Pakistan is simply paper-based method but some certain political and socio-economic issues turn that simple process in complicated and disputes once.Solutions of such problems are consisting of many methods including the e-voting system.The e-voting system facilitates the voters to cast their votes by electronic means with very easy and convenient way.This also allows maintaining the security and secrecy of the voter along with election process.Electronic voting reduces the human-involvement throughout the process from start to the end.Such system is not established yet in Pakistan.Hence,every election is disputed always.In this paper we proposed the framework of an e-voting system and simulation with the use of blockchain ledger technology.The proposed framework owns the capacity to deal with ballots in Pakistan.The novelty of the framework is that the e-voting system is linked to National Database and Registration Authority(NADRA)database which assures voter’s validation.The fundamental requirements were kept in consideration during the performance evaluation of the system.The results are processed and depicted specially with reference to the number of voters and voting stations,real time of vote casting,network bandwidth and controlling principles.The results support the decision makers and guide them in the foundation and customization of an e-voting system in Pakistan. | Shahid Hussain Danwar Javed Ahmed Mahar Aneela Kiran | 2022 | Computers, Materials & Continua2022，，7： | 0 |
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