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| 1 | Acute upper gastrointestinal bleeding in patients on long-term oral anticoagulation therapy: Endoscopic findings, clinical management and outcome显示文摘AIM: Acute gastrointestinal bleeding is a severe complication in patients receiving long-term oral anticoagulant therapy.The purpose of this study was to describe the causes and clinical outcome of these patients.METHODS: From January 1999 to October 2003, 111patients with acute upper gastrointestinal bleeding (AUGIB)were hospitalized while on oral anticoagulants. The causes and clinical outcome of these patients were compared with those of 604 patients hospitalized during 2000-2001with AUGIB who were not taking warfarin.RESULTS: The most common cause of bleeding was peptic ulcer in 51 patients (45%) receiving anticoagulants compared to 359/604 (59.4%) patients not receiving warfarin (P<0.05). No identifiable source of bleeding could be found in 33 patients (29.7%) compared to 31/604(5.1%) patients not receiving anticoagulants (P= 0.0001).The majority of patients with concurrent use of non-steroidal anti-inflammatory drugs (NSATDs) (26/35, 74.3%) had a peptic ulcer as a cause of bleeding while 32/76 (40.8%)patients not taking a great dose of NSATDs had a negative upper and lower gastrointestinal endoscopy. Endoscopic hemostasis was applied and no complication was reported.Six patients (5.4%) were operated due to continuing or recurrent hemorrhage, compared to 23/604 (3.8%) patients not receiving anticoagulants. Four patients died, the overall mortality was 3.6% in patients with AUGIB due to anticoagulants, which was not different from that in patients not receiving anticoagulant therapy.CONCLUSION: Patients with AUGIB while on long-term anticoagulant therapy had a clinical outcome, which is not different from that of patients not taking anticoagulants.Early endoscopy is important for the management of these patients and endoscopic hemostasis can be safely applied. | Konstantinos C Thomopoulos Konstantinos P Mimidis George J Theocharis Anthie G Gatopoulou Georgios N Kartalis Vassiliki N Nikolopoulou | 2005 | World Journal of Gastroenterology2005，11，9： | 5 |
| 2 | Consortia and knowledge management:The functional context and an organizational model显示文摘 | Anthi K | 2003 | Library Management2003，，6： | 1 |
| 3 | Massive rupture of a hepatic hydatid cyst associated with mechanical ventilation 显示文摘 | Anthi A Katsenos C Georgopoulou S | 2004 | Anesth Analg2004，98，3： | 1 |
| 4 | The length of the calmodulin linkerdetermines the extent of transient interdomain association andtarget affinity J显示文摘 | Anthis N J CIore G M | 2013 | Am Chem Soc2013，135，： | 1 |
| 5 | Cloning, expression, and characterization of a thermostable GH7 endoglu- canase from Myceliophthora thermophila capable of high-consistency enzymatic liquefaction 显示文摘 | Anthi C K Evangelos T Paul C | 2014 | Appl Mi- crobiol Biotechno12014，98，： | 1 |
| 6 | Use of Satellite Images for Fog Detection(AVHRR) and Forecast of Fog Dissipation (METEOSAT) over Lowland Thessalia, Hellas 显示文摘 | ANTHIS A I | 1999 | Remote Sensing1999，20，6： | 1 |
| 7 | Polo-like kinase confers MPF autoamplification competence to growing xenopus oocytes显示文摘 | Anthi K Anne CL Golbahar P et el | 2003 | Development2003，131，： | 1 |
| 8 | Health-related quality of life and disability in survivors of multiple trauma one year after intensive care unit discharge 显示文摘 | Dimopoulou loanna Anthi A Mastora Z | 2004 | Am J Phys Med Rehabil2004，83，3： | 1 |
| 9 | Fluid dynamic loading on curved riser pipes显示文摘 | Anthi Miliou Spencer J Sherwin J Michael R Graham | 2003 | Journal of Offshore Mechanics and Arctic Engineering2003，125，3： | 1 |
| 10 | Consortia and Knowledge management: The FunCtiOnal Context arid Organization Model显示文摘 | Anthi Katsirikou | 2003 | Library Management2003，24，67： | 1 |
| 11 | Portal, splenic and mesenteric vein thrombosis in a patient double heterozygous for factor V Leiden and prothrombin G20210A mutation显示文摘 | Elisavet Grouzi Marianna Politou Panagiota Douramani Efrosyni Merkouri Argyri Gialeraki Hlias Brountzos Georgios Perros Anthi Travlou | 2009 | Blood Coagulation & Fibrinolysis2009，，8： | 1 |
| 12 | Chaos in the library environment显示文摘 | Katsirikou Anthi Skiadas Christos H | 2001 | Library Management2001，22，6： | 1 |
| 13 | Functional status and quality of life in long-term survivors of cardiac arrest after cardiac surgery显示文摘 | Dimopolulon l Anthi A Michalis A | 2001 | Crit Care Med2001，29，： | 1 |
| 14 | Consortia and knowledge management:The functional context and an organizational mode显示文摘 | Anthi K | 2003 | Library Management2003，24，6： | 1 |
| 15 | The deubiquitinating en- zyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in arabidopsis thaliana 显示文摘 | Erika I Anthi K Isabel K M | 2010 | Plant Cell2010，22，： | 1 |
| 16 | Unexpected cardiac arrest after cardiac surgery: incidence, predisposing causes, and outcome of open chest cardiopulmonary resuscitation显示文摘 | TzelepisCE AlivizatosP | 1998 | Chest1998，113，1： | 1 |
| 17 | Functional status and quality of life in long-term survivors of cardiac arrest after cardiac surgery显示文摘 | Anthi A Michalis A | 2001 | Crit Care Med2001，29，7： | 1 |
| 18 | Prediction of prolonged ventilatory supportin blunt thoracic trauma patients显示文摘 | Dimopoulou I Anthi A Lignos M | 2003 | Intensive Care Med2003，29，： | 1 |
| 19 | Retinal vein occlusion: genetic predisposition and systemic risk factors显示文摘 | Kassiani Giannaki Marianna Politou Alexandros Rouvas Efrossyni Merkouri Anthi Travlou Panayiotis Theodosiadis Argyri Gialeraki | 2013 | Blood Coagulation & Fibrinolysis2013，，3： | 1 |
| 20 | Role of methylenetetrahydrofolate reductase 677C->T polymorphism in the development of premature myocardial infarction显示文摘 | Loukianos S. Rallidis Argiro Gialeraki Christoforos Komporozos Panagiotis Vavoulis Georgios Pavlakis Anthi Travlou Ioannis Lekakis Dimitrios T. Kremastinos | 2007 | Atherosclerosis2007，，1： | 1 |
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