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| 1 | Twenty-five years of research on the effects of exercise training in breast cancer survivors:A systematic review of the literature显示文摘AIM:To investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient population.METHODS:Pub Med, Medline Plus, the Cochrane Library, Web of Science, SportD iscus, Embase, Scorpus, and Google Scholar were searched from September to November 2013 to identify exercise training studies that used objective measurements of fitness and/or patient reported outcomes assessed pre and post-exercise training with statistical analyses performed in at least one of the following outcome measurements:Cardiorespiratory function, body composition, muscular strength, fatigue, depression, and overall quality of life. Five reviewers independently identified the studies that met the criteria for the review and discrepancies were resolved by consensus among all authors.RESULTS:Fifty-one studies were included in this review with 5 from the period between 1989-1999, 11 from 2000-2006, and 35 from 2007-2013. The evolution of study designs changed from aerobic only exercise training interventions(1989-1999), to a combination of aerobic and resistance training(2000-2006), to studies including an arm of resistance training or examining the effects of resistance training as the main mode of exercise(2007-2013). Overall, the benefits of exercise showed improvements in cardiorespiratory function, body composition, strength, and patient reported outcomes including fatigue, depression, and quality of life.CONCLUSION:Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise. | Claudio L Battaglini Robert C Mills Brett L Phillips Jordan T Lee Christina E Story Marcelo GB Nascimento Anthony Carl Hackney | 2014 | World Journal of Clinical Oncology2014，5，2： | 3 |
| 2 | Fondaparinux预防老年急性内科患者发生静脉血栓形成的效果与安全性:随机安慰剂对照研究显示文摘目的:观察 Fondaparinux 对具有中高度静脉血栓发生危险的老年急性内科住院患者的抗凝效果与安全性。设计:双盲随机安慰剂对照研究。背景:8个国家的35个中心。参与者:849例≥60岁内科患者,住院原因分别为充血性心力衰竭、慢性肺病合并急性呼吸系统疾患、急性炎症性或感染性疾病,预期至少住院4天以上。干预:2.5 mg Fondaparinux 或安慰剂,每天1次皮下注射,持续6~14天。观察指标:主要指标为静脉血栓形成(治疗后15天内采用双侧静脉造影检查)及有症状的静脉血栓;次要指标为死亡与出血。患者随访时间为1个月。结果:Fondaparinux 治疗组425例患者和安慰剂组414例患者接受了安全性分析(10例未治疗)。644例患者(75.9%)可接受主要指标分析。静脉血栓检出率在 Fondaparinux 治疗组为5.6%(18/321),安慰剂组为10.5%(34/323),相对危险减少46.7%(95% CI 7.7%~69.3%)。安慰剂组5例患者发生有症状的静脉血栓,Fondaparinux治疗组无患者发生有症状的静脉血栓(P=0.029)。两组均有1例(0.2%)患者发生严重出血。随访结束时,安慰剂组、Fondaparinux 治疗组分别死亡25(6.0%)、14(3.3%)例患者。结论:Fondaparinux 可有效预防急性内科老年患者无症状性及有症状的静脉血栓。严重出血几率两组相似。 | Alexander T Cohen Bruce L Davidson Alexander S Gallus Michael R Lassen Martin H Prins Witold Tomkowski Alexander G G Turpie Jan F M Egberts Anthonie W A Lensing 石汉平(译) 王深明(校) | 2006 | 英国医学杂志中文版2006，9，5： | 3 |
| 3 | Bovine immunoglobulin protein isolates for the nutritional management of enteropathy显示文摘The gastrointestinal tract is responsible for a multitude of digestive and immune functions which depend upon the balanced interaction of the intestinal microbiota, diet, gut barrier function, and mucosal immune response. Disruptions in one or more of these factors can lead to intestinal disorders or enteropathies which are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Enteropathy is frequently associated with human immunodeficiency virus(HIV) infection, inflammatory bowel disease, autoimmune enteropathy, radiation enteritis, and irritable bowel syndrome(IBS), where pathologic changes in the intestinal tract lead to abdominal discomfort, bloating, abnormal bowel function(e.g., diarrhea, urgency, constipation and malabsorption). Unfortunately, effective therapies for the management ofenteropathy and restoring intestinal health are still not available. An accumulating body of preclinical studies has demonstrated that oral administration of plasmaor serum-derived protein concentrates containing high levels of immunoglobulins can improve weight, normalize gut barrier function, and reduce the severity of enteropathy in animal models. Recent studies in humans, using serum-derived bovine immunoglobulin/protein isolate, demonstrate that such protein preparations are safe and improve symptoms, nutritional status, and various biomarkers associated with enteropathy. Benefits have been shown in patients with HIV infection or diarrhea-predominant IBS. This review summarizes preclinical and clinical studies with plasma/serum protein concentrates and describes the effects on host nutrition, intestinal function, and markers of intestinal inflammation. It supports the concept that immunoglobulin-containing protein preparations may offer a new strategy for restoring functional homeostasis in the intestinal tract of patients with enteropathy. | Bryon W Petschow Anthony T Blikslager Eric M Weaver Joy M Campbell Javier Polo Audrey L Shaw Bruce P Burnett Gerald L Klein J Marc Rhoads | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 4 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 5 | Growth of anaerobic rumen fungi on defined and semi-defined media lacking rumen fluid显示文摘 | Susane E L Michael K T Anthony P J T | 1985 | J General Microbiology1985，131，： | 1 |
| 6 | Estrogenic soybean isoflavones and chronic disease-risks and benefits显示文摘 | CLARKSON T B ANTHONY M S HUGHES C L | 1995 | Trends Endocrinol Metab1995，6，1： | 1 |
| 7 | Electron spin resonance detection of spin - trapped radicals formed during the glow- discharge electrolysis of aqueous solutions 显示文摘 | ANTHONY T DAVID L G MALCOLM D I | 1980 | J C S Faraday I1980，76，： | 1 |
| 8 | METALLIC URETERAL STENTS FOR THE MANAGEMENT OF BENIGN UPPER URINARY TRACT OBSTRUCTION显示文摘 | Hector L Lopez-Huertas Anthony J Polcari Alex Acosta-Miranda Thomas M t Turk | 2009 | The Journal of Urology2009，，4： | 1 |
| 9 | Soy isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys显示文摘 | Anthony M S Clarkson T B Hughes C L J Morgan T M Burke GL | 1996 | J Nutr1996，126，1： | 1 |
| 10 | Rapid diagnosis of bac- teria by universal amplification of 23S ribosomal DNA followed by hybridization to an oligonucleotide array 显示文摘 | Anthony R M Brown T J French G L | 2000 | J Clin Microbiol2000，38，： | 1 |
| 11 | Rapid diagnosis of bacteremia by universal amplification of 23S ribosomal DNA followed by hybridization to an oligonueleotide array显示文摘 | Anthony R M /]rown T J French G L | 2000 | J Clin Microbio2000，38，78： | 1 |
| 12 | Morphological characteristics of reconstructed prime farmland soils in western Pennsylvania显示文摘 | Bell J C Cunningham R L Anthony C T | | 0，，03： | 1 |
| 13 | Soybean isoflavones improvecardiovascular risk factors without affecting the reproductive system ofperipubertal rhesus monkeys显示文摘 | ANTHONY M S CLARKSON T B HUGHES JR C L | 1996 | J Nutr1996，126，： | 1 |
| 14 | A single solution method for converting 2D assembly drawings to 3D part drawings显示文摘 | Tanaka M Anthony L Kaneeda T | 2004 | Computer-Aided Design2004，36，8： | 1 |
| 15 | Soybean isoflavones improve cardiovascular risk fac- tors without affecting reproductive system of peripu- bertal rhesus monkeys 显示文摘 | Anthony M S Clarkson T B Hughes Jr C L | 1996 | Journal of Nutrition1996，126，1： | 1 |
| 16 | Return on Quality ( ROQ ) : Making Service Quality Financially Accountable 显示文摘 | Rust Roland T Anthony J Zahorik Timothy L Keiningham | 1995 | Journal of Marketing1995，59，2： | 1 |
| 17 | Rapid diagnosis of bacteremia by universal amplification of 23S ribosomal DNAfollowed by hybridization to an oligonucleotide array显示文摘 | Anthony R M Brown T J French G L | 2000 | JClin Microbiol2000，38，： | 1 |
| 18 | A dual arsenic speciation system combining liquid chromatographic and purge and trap gas chro matographic separation with atomic fluorescence spectrometric detection显示文摘 | Zdenka L Johannes T van Elteren Anthony R Byrne | 1998 | Analytica Chimica Acta1998，358，1： | 1 |
| 19 | Factors affecting recurrence following incisional hemiorrhaphy显示文摘 | ANTHONY T BERGEN P C KIM L T | 2000 | World J Surg2000，24，1： | 1 |
| 20 | An alternative method using digital cameras for continuous monitoring of crop status 显示文摘 | Sakamoto T Anatoly A Anthony L | 2012 | Agricultural and Forest Meteorology2012，，2012： | 1 |
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