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| 1 | Motor network reorganization in stroke patients with dyskinesias during a shoulder-touching task:A fNIRS study显示文摘Hemiplegia after stroke has become a major cause of the world's high disabilities,and it is vital to enhance our understanding of post-stroke neuroplasticity to develop e±cient rehabilitation programs.This study aimed to explore the brain activation and network reorganization of the motor cortex(MC)with functional near-infrared spectroscopy(fNIRS).The MC hemodynamic signals were gained from 22 stroke patients and 14 healthy subjects during a shoulder-touching task with the right hand.The MC activation pattern and network attributes analyzed with the graph theory were compared between the two groups.The results revealed that healthy controls presented dominant activation in the left MC while stroke patients exhibited dominant activation in the bilateral hemispheres MC.The MC networks for the two groups had small-world properties.Compared with healthy controls,patients had higher transitivity and lower global e±ciency(GE),mean connectivity,and long connections(LCs)in the left MC.In addition,both MC activation and network attributes were correlated with patient's upper limb motor function.The results showed the stronger compensation of the unaffected motor area,the better recovery of the upper limb motor function for patients.Moreover,the MC network possessed high clustering and relatively sparse inter-regional connections during recovery for patients.Our results promote the understanding of MC reorganization during recovery and indicate that MC activation and network could provide clinical assessment signi¯cance in stroke patients.Given the advantages of fNIRS,it shows great application potential in the assessment and rehabilitation of motor function after stroke. | Yizheng Zhang Dan Wang Dongyang Wang Kecheng Yan Li Yi Shuoshu Lin Guangjian Shao Zhiyong Shao Jinyan Sun Aoran Yang | 2023 | Journal of Innovative Optical Health Sciences2023，16，6： | 1 |
| 2 | Separation performance of multi-components solution by membrane technology in continual diafiltration mode显示文摘 | Liming Zhao Hefei Zhao Phuongbinh Nguyen Aoran Li Lihua Jiang Quanming Xia Yi Rong Yongjun Qiu Jiachun Zhou | 2013 | Desalination2013，，： | 1 |
| 3 | TDF Promotes Glycolysis and Mitochondrial Dysfunction to Accelerate Lactate Accumulation by Downregulating PGC1α in Mice显示文摘Tenofovir disoproxil fumarate(TDF),is a product of tenofovir and has been recommended for long-term use by guidelines1 because of its favorable efficacy in the treatment of human immunodeficiency virus(HIV)and hepatitis B virus(HBV)infection.Hence,a better understanding of the safety profiles of long-term TDF use is extremely important.Lactic acidosis,as a rare but fatal adverse event of TDF,were reported both in HIV-infected patients,2-4 and in CHB patients.5-7 Hyperlactatemia occurred in 15.6%HIV-infected patients using TDF in a Cameroon cohort study8 and was 3%in another South Africa cohort study.9 Therefore,TDF increases the risk of abnormal serum lactate,but the mechanism is unclear. | Yuxuan Luo Zhiwei Chen Zhao Li Aoran Luo Yi Zeng Min Chen Mingli Peng Hong Ren Peng Hu | 2023 | Journal of Clinical and Translational Hepatology2023，11，4： | 0 |
| 4 | Mechanical responses of anchoring structure under triaxial cyclic loading显示文摘Dynamic load on anchoring structures(AS)within deep roadways can result in cumulative damage and failure.This study develops an experimental device designed to test AS under triaxial loads.The device enables the investigation of the mechanical response,failure mode,instability assessment criteria,and anchorage effect of AS subjected to combined cyclic dynamic-static triaxial stress paths.The results show that the peak bearing strength is positively correlated with the anchoring matrix strength,anchorage length,and edgewise compressive strength.The bearing capacity decreases significantly when the anchorage direction is severely inclined.The free face failure modes are typically transverse cracking,concave fracturing,V-shaped slipping and detachment,and spallation detachment.Besides,when the anchoring matrix strength and the anchorage length decrease while the edgewise compressive strength,loading rate,and anchorage inclination angle increase,the failure intensity rises.Instability is determined by a negative tangent modulus of the displacement-strength curve or the continued deformation increase against the general downward trend.Under cyclic loads,the driving force that breaks the rock mass along the normal vector and the rigidity of the AS are the two factors that determine roadway stability.Finally,a control measure for surrounding rock stability is proposed to reduce the internal driving force via a pressure relief method and improve the rigidity of the AS by full-length anchorage and grouting modification. | Peng Wang Nong Zhang Qun Wei Xingliang Xu Guangzhen Cui Aoran Li Sen Yang Jiaguang Kan | 2024 | Journal of Rock Mechanics and Geotechnical Engineering2024，16，2： | 0 |
| 5 | An Improved Distributed Query for Large-Scale RDF Data显示文摘The rigid structure of the traditional relational database leads to data redundancy,which seriously affects the efficiency of the data query and cannot effectively manage massive data.To solve this problem,we use distributed storage and parallel computing technology to query RDF data.In order to achieve efficient storage and retrieval of large-scale RDF data,we combine the respective advantage of the storage model of the relational database and the distributed query.To overcome the disadvantages of storing and querying RDF data,we design and implement a breadth-first path search algorithm based on the keyword query on a distributed platform.We conduct the LUBM query statements respectively with the selected data sets.In experiments,we compare query response time in different conditions to evaluate the feasibility and correctness of our approaches.The results show that the proposed scheme can reduce the storage cost and improve query efficiency. | Aoran Li Xinmeng Wang Xueliang Wang Bohan Li | 2020 | Journal on Big Data2020，2，4： | 0 |
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