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| 1 | Pediatricians lack knowledge for the diagnosis and management of functional constipation in children over 6 mo of age显示文摘AIM To assess the knowledge of general pediatricians througout Indonesia about the diagnosis and treatment of childhood constipation.METHODS A comprehensive questionnaire was distributed to general pediatricians from several teaching hospitals and government hospitals all over Indonesia.RESULTS Data were obtained from 100 pediatricians, with a mean of 78.34 ± 18.00 mo clinical practice, from 20 cities throughout Indonesia. Suspicion of constipation in a child over 6 mo of age arises when the child presents with a decreased frequency of bowel movements(according to 87% of participants) with a mean of one bowel movement per 3.59 ± 1.0 d, hard stools(83%), blood in the stools(36%), fecal incontinence(33%), and/or difficulty in defecating(47%). Only 26 pediatricians prescribe pharmacologic treatment as first therapeutic approach, while the vast majority prefers nonpharmacologic treatment, mostly(according to 68%) The preferred nonpharmacologic treatment are high-fiber diet(96%), increased fluid intake(90%), toilet training(74%), and abdominal massage(49%). Duration of non-pharmacological treatment was limited to 1 to 2 wk. Seventy percent of the pediatricians recommending toilet training could only mention some elements of the technique, and only 15% was able to explain it fully and correctly. Lactulose is the most frequent pharmacologic intervention used(87% of the participants), and rectal treatment with sodium citrate, sodium lauryl sulfo acetate, and sorbitol is the most frequent rectal treatment(85%). Only 51% will prescribe rectal treatment for fecal impaction. The majority of the pediatricians(69%) expect a positive response during the first week with a mean(± SD) of 4.1(± 2.56) d. Most participants(86%) treat during one month or even less. And the majority(67%) stops treatment when the frequency and/or consistency of the stools have become normal, or if the patient had no longer complaints.CONCLUSION These data provide an insight on the diagnosis and management of constipation in childhood in Indonesia. Although general pediatricians are aware of some important aspects of the diagnosis and mangement of constipation, overall knowledge is limited. Efforts should be made to improve the distribution of existing guidelines. These findings highlight and confirm the difficulties in spreading existing information from guidelines to general pediatricians. | Ariani Widodo Badriul Hegar Yvan Vandenplas | 2018 | World Journal of Clinical Pediatrics2018，7，1： | 6 |
| 2 | Proteomic analysisof Populus euramericana ( clone 1-214) roots to identify key fac-tors involved in zinc stress response 显示文摘 | ROMEO S TRUPIANO D ARIANI A | 2014 | Journal of Plant Physiol-ogy2014，171，12： | 1 |
| 3 | CDKL5/STK9 is mutated in Rett syndrome variant with infantile spasms显示文摘 | Scala E Ariani F Mari F | 2005 | J Med Genet2005，42，： | 1 |
| 4 | Probioties for preventing ventilator-associated pneumonia: a systematic review and recta- analysis of high-quality randomized controlled trials显示文摘 | Wang J Liu KX Ariani F | 2013 | PloS One2013，8，83： | 1 |
| 5 | Plant growth-promotingbacteria as biofertilizer显示文摘 | Hafeez F Y Yasmin S Ariani D | | 0，，： | 1 |
| 6 | Noninvasive ventilation in acute cardiogenic pulmonary edema: a meta - analysis of randomized controlled trials 显示文摘 | ariani J Macchia A Belziti C | 2011 | J Card Fail2011，17，10： | 1 |
| 7 | New development of carbonate apatite-chitosan scaffold based on lyophilization technique for bone tissue engineering显示文摘 | Ariani MD Matsuura A Hirata I | 2013 | Dent Mater J2013，32，2： | 1 |
| 8 | The XLMR gene ACSL4 plays a role in dendritic spine architecture显示文摘 | I. Meloni V. Parri R. De Filippis F. Ariani R. Artuso M. Bruttini E. Katzaki I. Longo F. Mari C. Bellan C.G. Dotti A. Renieri | 2009 | Neuroscience2009，，2： | 1 |
| 9 | Plant growth-promoting bacteria as biofertilizer显示文摘 | Hafeez F Y Yasmin S Ariani D | 2006 | Agronomy for Sustainable Development2006，26，： | 1 |
| 10 | Histopathologic validation of angioscopy and intravascular ultrasound显示文摘 | Siegel RJ Ariani M Fishbein MC | | 0，，： | 1 |
| 11 | Plant growth -promoting bacteria as biofertilizer显示文摘 | Hafeez FY Yasmin S Ariani D | 2006 | Agronomy Sustainable Development2006，26，： | 1 |
| 12 | Plant growth-promoting bacteria as biofertilizer显示文摘 | Hafeez F Y Yasmin S Ariani D | 2006 | Agronomy Sustainable Development2006，26，： | 1 |
| 13 | Probiotics for preventing wntilatm - associated pneumonia: A systematic review and Meta analysis of high- quality randomized controlled trials 显示文摘 | Wang J Liu K Ariani F | 2013 | Salloh PLoS One2013，8，83： | 1 |
| 14 | Dissolution of peripheral arterial thrombi by ultrasound显示文摘 | ARIANI M | 1991 | Circulation1991，84，4： | 1 |
| 15 | FOXG1 is responsible for the congennital varient of Rett syndrome显示文摘 | Ariani F Hayek G Rindinella D | 2010 | Nuerogenetics2010，83，1： | 1 |
| 16 | Induction of male sterile in plants by a chimaric ribonuclease gene显示文摘 | M ariani C BenckelerM D Truetter J | 1990 | Nature1990，347，： | 1 |
| 17 | Glucoeorticosteroid in treat- ment of severe pneumonia显示文摘 | Ariani F Liu K Jing Z | 2013 | Mediators Inflamm2013，2013，86： | 1 |
| 18 | Diabeticnephropathy: an u p d ate显示文摘 | G ariani K d e Seigneux S Pechbre-B ertschi A e t al | 2012 | Rev M ed Suisse2012，8，330： | 1 |
| 19 | Glucocorticosteroid in treatment ofsevere pneumonia显示文摘 | Ariani F Liu K Jing Z | 2013 | Mediators Inflamm2013，2013，86： | 1 |
| 20 | Dissolution of peripheral arterial thrombi by ultrasound显示文摘 | Fishbein MC Chae JS | 1991 | Circulation1991，84，： | 1 |
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