|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Management of negative pressure wound therapy in the treatment of diabetic foot ulcers显示文摘Diabetic foot(DF) is a common complication of diabetes and the first cause of hospital admission in diabetic patients. In recent years several guidelines have been proposed to reinforce the the management of DF with a notable increase in diabetes knowledge and an overall reduction of amputations. Significant improvements have been reached in the treatment of diabetic foot ulcers(DFUs) and nowadays clinicians have several advanced medications to apply for the best local therapy. Among these, negative pressure wound therapy(NPWT) is a useful adjunct in the management of chronic and complex wounds to promote healing and wound bed preparation for surgical procedures such as skin grafts and flap surgery. NPWT has shown remarkable results although its mechanisms of action are not completely understood. In this paper, we offer a complete overview of this medication and its implication in the clinical setting. We have examined literature related to NPWT concerning human, animal and in vitro studies, and we have summarized why, when and how we can use NPWT to treat DFUs. Further we have associated our clinical experience to scientific evidence in the field of diabetic foot to identify a defined strategy that could guide clinician in the use of NPWT approaching to DFUs. | Marco Meloni Valentina Izzo Erika Vainieri Laura Giurato Valeria Ruotolo Luigi Uccioli | 2015 | World Journal of Orthopedics2015，6，4： | 33 |
| 2 | Photosynthesis and activity of superoxide dismutase, peroxidase and glutathione reductase in cotton under salt stress显示文摘 | Diego A. Meloni Marco A. Oliva Carlos A. Martinez José Cambraia | 2002 | Environmental and Experimental Botany2002，，1： | 6 |
| 3 | Osteomyelitis in diabetic foot:A comprehensive overview显示文摘Foot infection is a well recognized risk factor for major amputation in diabetic patients. The osteomyelitis is one of the most common expression of diabetic foot infection, being present approximately in present in 10%-15% of moderate and in 50% of severe infectious process. An early and accurate diagnosis is required to ensure a targeted treatment and reduce the risk of major amputation. The aim of this review is to report a complete overview about the management of diabetic foot osteomyelitis. Epidemiology, clinical aspects, diagnosis and treatment are widely described according to scientific reccomendations and our experience. | Laura Giurato Marco Meloni Valentina Izzo Luigi Uccioli | 2017 | World Journal of Diabetes2017，8，4： | 5 |
| 4 | Contrast-enhanced ultrasound Liver Imaging Reporting and Data System:Lights and shadows in hepatocellular carcinoma and cholangiocellular carcinoma diagnosis显示文摘BACKGROUND Contrast-enhanced ultrasound(CEUS)is considered a secondary examination compared to computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of hepatocellular carcinoma(HCC),due to the risk of misdiagnosing intrahepatic cholangiocarcinoma(ICC).The introduction of CEUS Liver Imaging Reporting and Data System(CEUS LI-RADS)might overcome this limitation.Even though data from the literature seems promising,its reliability in real-life context has not been well-established yet.AIM To test the accuracy of CEUS LI-RADS for correctly diagnosing HCC and ICC in cirrhosis.METHODS CEUS LI-RADS class was retrospectively assigned to 511 nodules identified in 269 patients suffering from liver cirrhosis.The diagnostic standard for all nodules was either biopsy(102 nodules)or CT/MRI(409 nodules).Common diagnostic accuracy indexes such as sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)were assessed for the following associations:CEUS LR-5 and HCC;CEUS LR-4 and 5 merged class and HCC;CEUS LR-M and ICC;and CEUS LR-3 and malignancy.The frequency of malignant lesions in CEUS LR-3 subgroups with different CEUS patterns was also determined.Inter-rater agreement for CEUS LI-RADS class assignment and for major CEUS pattern identification was evaluated.RESULTS CEUS LR-5 predicted HCC with a 67.6%sensitivity,97.7%specificity,and 99.3%PPV(P<0.001).The merging of LR-4 and 5 offered an improved 93.9%sensitivity in HCC diagnosis with a 94.3%specificity and 98.8%PPV(P<0.001).CEUS LR-M predicted ICC with a 91.3%sensitivity,96.7%specificity,and 99.6%NPV(P<0.001).CEUS LR-3 predominantly included benign lesions(only 28.8%of malignancies).In this class,the hypo-hypo pattern showed a much higher rate of malignant lesions(73.3%)than the iso-iso pattern(2.6%).Inter-rater agreement between internal raters for CEUS-LR class assignment was almost perfect(n=511,k=0.94,P<0.001),while the agreement among raters from separate centres was substantial(n=50,k=0.67,P<0.001).Agreement was stronger for arterial phase hyperenhancement(internal k=0.86,P<2.7×10-214;external k=0.8,P<0.001)than washout(internal k=0.79,P<1.6×10-202;external k=0.71,P<0.001).CONCLUSION CEUS LI-RADS is effective but can be improved by merging LR-4 and 5 to diagnose HCC and by splitting LR-3 into two subgroups to differentiate iso-iso nodules from other patterns. | Gianpaolo Vidili Marco Arru Giuliana Solinas Diego Francesco Calvisi Pierluigi Meloni Assunta Sauchella Davide Turilli Claudio Fabio Antonio Cossu Giordano Madeddu Sergio Babudieri Maria Assunta Zocco Giovanni Iannetti Enza Di Lembo Alessandro Palmerio Delitala Roberto Manetti | 2022 | World Journal of Gastroenterology2022，28，27： | 3 |
| 5 | Low-dose computed tomography with 4th-generation iterative reconstruction algorithm in assessment of oncologic patients显示文摘AIM To compare radiation dose and image quality of lowdose computed tomography(CT) protocol combined with hybrid-iterative reconstruction algorithm with standarddose CT examinations for follow-up of oncologic patients. METHODS Fifty-one patients with known malignant diseases which underwent, during clinical follow-up, both standarddose and low-dose whole-body CT scans were enrolled. Low-dose CT was performed on 256-row scanner, with 120 kV and automated m A modulation, and iterative reconstruction algorithm. Standard-dose CT was performed on 16-rows scanner, with 120 kV, 200-400 m As(depending on patient weight). We evaluated density values and signal-to-noise ratio, along with image noise(SD), sharpness and diagnostic quality with 4-point scale.RESULTS Density values in liver, spleen and aorta were higher in lowdose images(liver 112.55 HU vs 103.90 HU, P < 0.001), as SD values in liver and spleen(liver 16.81 vs 14.41). Volumetric-Computed-Tomographic-Dose-Index(CTDIvol) and Dose-Length-Product(DLP) were significantly lower in low-dose CT as compared to standard-dose(DLP 1025.6 m Gy*cm vs 1429.2 m Gy*cm, P < 0.001) with overall dose reduction of 28.9%. Qualitative analysis did not reveal significant differences in image noise and diagnostic quality.CONCLUSION Automatic tube-current modulation combined with hybriditerative algorithm allows radiation dose reduction of 28.9% without loss of diagnostic quality, being useful in reducing dose exposure in oncologic patients. | Davide Ippolito Alessandra Silvia Casiraghi Cammillo Talei Franzesi Davide Fior Franca Meloni Sandro Sironi | 2017 | World Journal of Gastrointestinal Oncology2017，9，10： | 2 |
| 6 | Complications of Microwave Ablation for Liver Tumors: Results of a Multicenter Study显示文摘 | Tito Livraghi Franca Meloni Luigi Solbiati Giorgio Zanus | 2012 | CardioVascular and Interventional Radiology2012，，4： | 2 |
| 7 | Evaluation of posttreatment response of hepatocellular carcinoma: comparison of ultrasonography with second-generation ultrasound contrast agent and multidetector CT显示文摘 | Giuseppe Salvaggio Antonella Campisi Vito Greco Isidoro Cannella Maria Franca Meloni Giuseppe Caruso | 2010 | Abdominal Imaging2010，，4： | 2 |
| 8 | Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia显示文摘 | Andrea Caporali Marco Meloni Christine V?llenkle Desiree Bonci Graciela B. Sala-Newby Roberta Addis Gaia Spinetti Sergio Losa Rachel Masson Andrew H. Baker Reuven Agami Carlos le Sage Gianluigi Condorelli Paolo Madeddu Fabio Martelli Costanza Emanueli | 2011 | Circulation2011，，3： | 2 |
| 9 | Identification of the prosurvival activity of nerve growth factor on cardiac myocytes显示文摘 | Caporali A Sala-Newby GB Meloni M | 2008 | Cell Death Differ2008，15，2： | 1 |
| 10 | Hepatocelluar carcinomn:Radio- frequency ablation of medion and large lesions 显示文摘 | Livraghi T Meloni F Goldberg SN | 2000 | Radiology2000，214，： | 1 |
| 11 | Complete development and long-term maintenance of Cryptosporidium parvum human and cattle genotypes in cell culture显示文摘 | Hijjawi NS Meloni BP Morgan UM | 2001 | Int J Parasitol2001，31，10： | 1 |
| 12 | Identification of the prosurvival activity of nerve growth factor on cardiac myo- eytes 显示文摘 | Caporali A Sala-Newby GB Meloni M | 2008 | Cell Death Differ2008，15，2： | 1 |
| 13 | A second hysterosalpingography reduces the use of selective technique for treatment of a proximal tubal obstruction显示文摘 | Dessole S Meloni GB Capobianco G | 2000 | Fertil Steril2000，73，5： | 1 |
| 14 | Establishment of neuronal in vitro models of ischemia in 96-well microtiter strip-plates that result in acute, progressive and delayed neuronal death显示文摘 | B.P Meloni B.T Majda N.W Knuckey | 2001 | Neuroscience2001，，1： | 1 |
| 15 | Ultra- sound-guide mammotome vacuum biopsy for the diagnosis of impalpable breast leisions显示文摘 | MELONI GB DESSOLE S BECCHERE MP | 2001 | Ultrasound Obstet Gynecol2001，18，5： | 1 |
| 16 | Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellularcarcinoma in cirrhosis:is resection still the treatment of choice?显示文摘 | Livraghi T Meloni F Di Stasi M | 2008 | Hepatology2008，47，1： | 1 |
| 17 | The Assessment of IFN-gamma and its Regulatory Cytokines in the Plasma and Bronchoalveolar Lavage Fluid of Patients with Active Pulmonary Tuberculosis显示文摘 | Morosini M Meloni F Marone Bianco A | 2003 | Int J Tuberc Lung Dis2003，7，10： | 1 |
| 18 | Interleukin-2 may induce prolonged remissons in advanced acute myelogenous leukemia显示文摘 | Foa R Vignetti M | 1994 | Blood1994，84，： | 1 |
| 19 | Ultrasound-guided mammotome vacuum biopsy for the diagnosis of impalpable breast lesions显示文摘 | Meloni G B Dessole S Becchere M P | 2001 | Ultrasound Obstet Gynecol2001，18，5： | 1 |
| 20 | Characterisation of neumnal cell death in acute and delayed in vitro ischemia(oxygen-glucose deprivation) models显示文摘 | Meloni BP Meade AJ Kitikomolsuk D etal | 2011 | Neumsci Methods2011，195，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员