| 5 | Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response显示文摘Loss of follow-up or reinfections hinder the expectations of hepatitis C eradicationdespite the existence of highly effective treatments. Moreover, the elimination ofthe infection does not imply the reversion of those chronic alterations derivedfrom the previous infection by hepatitis C virus (HCV). This review analyzes therisk factors associated with loss to follow-up in diagnosis or treatment, and thepossibility of reinfection. Likewise, it assesses the residual alterations induced bychronic HCV infection considering the liver alterations (inflammation, fibrosis,risk of decompensation, hepatocellular carcinoma, liver transplantation) and, onthe other hand, the comorbidities and extrahepatic manifestations (cryoglobulinemia,non-Hodgkin lymphoma, peripheral insulin resistance, and lipid, boneand cognitive alterations). Peculiarities present in subjects coinfected with humanimmunodeficiency virus are analyzed in each section. | Sara Cuesta-Sancho Mercedes Márquez-Coello Francisco Illanes-Álvarez Denisse Márquez-Ruiz Ana Arizcorreta Fátima Galán-Sánchez Natalia Montiel Manuel Rodriguez-Iglesias José-Antonio Girón-González | 2022 | World Journal of Hepatology2022，14，1： | 0 |
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