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| 1 | Hepatitis B-related events in autologous hematopoietic stem cell transplantation recipients显示文摘AIM: To investigate the frequency of occult hepatitis B, the clinical course of hepatitis B virus (HBV) reactivation and reverse seroconversion and associated risk factors in autologous hematopoietic stem cell transplantation (HSCT) recipients. METHODS: This study was conducted in 90 patients undergoing autologous HSCT. Occult HBV infection was investigated by HBV-DNA analysis prior to transplantation, while HBV serology and liver function tests were screened prior to and serially after transplantation. HBV-related events including reverse seroconversion and reactivation were recorded in all patients. RESULTS: None of the patients had occult HBV prior to transplantation. Six (6.7%) patients were positivefor HBV surface antigen (HBsAg) prior to transplantation and received lamivudine prophylaxis; they did not develop HBV reactivation after transplantation. Clinical HBV infection emerged in three patients after transplantation who had negative HBV-DNA prior to HSCT. Two of these three patients had HBV reactivation while one patient developed acute hepatitis B. Three patients had anti-HBc as the sole hepatitis B-related antibody prior to transplantation, two of whom developed hepatitis B reactivation while none of the patients with antibody to HBV surface antigen (anti-HBs) did so. The 14 anti-HBs-and/or anti-HBc-positive patients among the 90 HSCT recipients experienced either persistent (8 patients) or transient (6 patients) disappearance of anti-HBs and/or anti-HBc. HBsAg seroconversion and clinical hepatitis did not develop in these patients. Female gender and multiple myeloma emerged as risk factors for loss of antibody in regression analysis (P < 0.05). CONCLUSION: Anti-HBc as the sole HBV marker seems to be a risk factor for reactivation after autologous HSCT. Lamivudine prophylaxis in HbsAg-positive patients continues to be effective. | zcan eneli Zübeyde Nur zkurt Kadir Acar Seyyal Rota Sahika Zeynep Aki Zeynep Arzu Yegin Münci Yagci Seren zenirler Gülsan Türkz Sucak | 2010 | World Journal of Gastroenterology2010，16，14： | 3 |
| 2 | Axonal Growth Is Sensitive to the Levels of Katanin,a Protein That Severs Microtubules显示文摘 | Arzu K Wenqian Y Joanna M S | 2004 | J Neurosci2004，24，25： | 1 |
| 3 | Reasons for Early Loss of Primary Molars显示文摘 | Gülsüm Ak/Elif Sepet/Arzu Pina/Gamze | | 0，，03： | 1 |
| 4 | The effects of propofol infu- sion on hepatic and pancreatic function and acid base status in children undergoing craniotomy and receiving phenytoin显示文摘 | Hatice T Arzu M Ozge K | 2009 | Anesth Analg2009，109，36： | 1 |
| 5 | Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL21 deficiency显示文摘 | Elisabeth Salzer Aydan Kansu Heiko Sic Peter Májek Aydan Ikincio?ullari Figen E. Dogu Nina Kathrin Prengemann Elisangela Santos-Valente Winfried F. Pickl Ivan Bilic Sol A. Ban Zarife Kulo?lu Arzu Meltem Demir Arzu Ensari Jacques Colinge Marta Rizzi Herman | 2014 | The Journal of Allergy and Clinical Immunology2014，，： | 1 |
| 6 | Histology of microscopic colitis—review with a practical approach for pathologists显示文摘 | Cord Langner Daniela Aust Arzu Ensari Vincenzo Villanacci Gabriel Becheanu Stephan Miehlke Karel Geboes Andreas Münch | 2015 | Histopathology2015，，5： | 1 |
| 7 | An entirely echo- guided technique for totally implantable access port positioning显示文摘 | Arzu GD Coccolini F Rossi M | 2014 | Indi- an J Surg2014，76，3： | 1 |
| 8 | Impact of sex on the outcomes of deceased donor liver transplantation显示文摘BACKGROUND Data examining the impact of sex on liver transplant(LT)outcomes are limited.It is clear that further research into sex-related differences in transplant patients is necessary to identify areas for improvement.Elucidation of these differences may help to identify specific areas of focus to improve on the organ matching process,as well as the peri-and post-operative care of these patients.AIM To utilize data from a high-volume Eurotransplant center to compare characteristics of male and female patients undergoing liver transplant and assess association between sex-specific variables with short-and long-term post-transplant outcomes.METHODS A retrospective review of the University of Essen’s transplant database was performed with collection of baseline patient characteristics,transplant-related data,and short-term outcomes.Comparisons of these data were made with Shapiro-Wilk,Mann-Whitney U,χ2 and Bonferroni tests applied where appropriate.A P value of<0.05 was accepted as statistically significant.RESULTS Of the total 779 LT recipients,261(33.5%)were female.Female patients suffered higher incidences of acute liver failure and lower incidences of alcohol-related or viremic liver disease(P=0.001).Female patients were more likely to have received an organ from a female donor with a higher donor risk index score,and as a high urgency offer(all P<0.05).Baseline characteristics of male and female recipients were also significantly different.In multivariate hazard regression analysis,recipient lab-Model for End-Stage Liver Disease score and donor cause of death were associated with long-term outcomes in females.Pre-operative diagnosis of hepatocellular carcinoma,age at time of listing,duration of surgery,and units transfused during surgery,were associated with long-term outcomes in males.Severity of complications was associated with long-term outcomes in both groups.Overall survival was similar in both males and females;however,when stratified by age,females<50 years of age had the best survival.CONCLUSION Female and male LT recipients have different baseline and transplant-related characteristics,with sex-specific variables which are associated with long-term outcomes.Female recipients<50 years of age demonstrated the best long-term outcomes.Pre-and post-transplant practices should be individualized based on sex-specific variables to optimize long-term outcomes. | Oya M Andacoglu Isabel S Dennahy Nicole C Mountz Luisa Wilschrey Arzu Oezcelik | 2024 | World Journal of Transplantation2024，14，1： | 0 |
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