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| 1 | Effects of glutamine and curcumin on bacterial translocation in jaundiced rats显示文摘AIM: To investigate the effect of curcumin on bacterial translocation and oxidative damage in an obstructive jaundice model and compare the results to glutamine, an agent known to be effective and clinically used. METHODS: Twenty-four female Wistar-Albino rats, weighing 200-250 g, were randomly divided into three groups (8 in each group). After ligation of the common bile duct in all animals, GroupⅠ received oral normal saline, Group Ⅱ received oral glutamine and Group Ⅲ received oral curcumin for seven days. Blood samples via cardiac puncture, tissue samples (terminal ileum, liver and mesenteric lymph node) and peritoneal fluid were obtained from the animals at the time of death to investigate bacterial translocation and oxidative damage. RESULTS: We observed that both glutamine and curcumin reduced bacterial translocation in blood, hepatocellular damage, plasma cytokine levels, oxidative tissue damage and apoptosis significantly compared to the control group. Additionally, glutamine showed protective effects on ileal epithelium and reduced villus atrophy. CONCLUSION: On the basis of these findings, both curcumin and glutamine are thought to be effective in preventing or reducing bacterial translocation and oxidative damage in obstructive jaundice. | Oguzhan Karatepe Ersin Acet Muharrem Battal Gokhan Adas Ahu Kemik Merih Altiok Gulcin Kamali Safiye Koculu Atahan Catay Sedat Kamali Servet Karahan | 2010 | World Journal of Gastroenterology2010，16，34： | 5 |
| 2 | Behavior ofPVA fiber-reinforced cementitious composites under static and impact Eexural effects显示文摘 | ATAHAN H N TUNCEL E Y PEKMEZCI B Y | 2013 | Journal of Materials in Civil Engineering2013，25，10： | 1 |
| 3 | Computer simulation of recycled content guardrail post impacts 显示文摘 | Atahan A O Ross H E J | 2004 | Transportation Engineering2004，130，6： | 1 |
| 4 | Crash testing and evaluation of a new generation L1 containment level guardrail 显示文摘 | ATAHAN A O YOCEL A 13 ERDEM M M | 2014 | Engineering Failure Analysis2014，38，： | 1 |
| 5 | Acute phase response during radiotherapy 显示文摘 | Cengiz M Akbulut S Atahan I L | 2001 | Int J Radiat Oncol Biol Phys2001，49，4： | 1 |
| 6 | Zoledronic acid con- current with either high-or reduced-dose palliative radio- therapy in the management of the breast cancer patients with bone metastases: a phase IV randomized clinical study显示文摘 | Atahan L Yildiz F Cengiz M | 2010 | Support Care Cancer2010，18，6： | 1 |
| 7 | Successful treat ment of verruca plantaris with a single sublesional injection of interferonalpha2a显示文摘 | Aksakal AA Ozden MG Atahan C | 2009 | Clin Exp DermatoI2009，34，1： | 1 |
| 8 | Zoledronic acid concurrent with either high-or reduced-dose palliative radiotherapy in the management of the breast cancer patients with bone metastases:a phase IV randomized clinical study显示文摘 | Atahan L Yildldiz F Cengiz M | | 0，，06： | 1 |
| 9 | Acute phase response during radiotherapy显示文摘 | Mustafa Cengiz Serap Akbulut I.Lale Atahan Perry W Grigsby | 2001 | International Journal of Radiation Oncology Biology Physics2001，，4： | 1 |
| 10 | Successful treatment of ver-ruca plantaris with a single sublesional injection of interferon-al-pha2a 显示文摘 | Aksakal AB Ozden MG Atahan C | 2009 | Clin Exp Dermatol2009，34，1： | 1 |
| 11 | Percent positive axillary lymph node metastasis predicts survival in patients with nonmetastatic breast cancer 显示文摘 | Lale Atahan I Yildiz F Ozyigit G | 2008 | Breast J2008，14，3： | 1 |
| 12 | Computer simulation of recycled content guardrail post impacts 显示文摘 | ATAHAN A O ROSS H E | 2004 | Journal of Transportation Engineering2004，130，6： | 1 |
| 13 | Is apolipoprotein-(a) an important indicator of vasculogenic erectile dysfunction 显示文摘 | Atahan O Kayigil O Hizel N | 1998 | Int Urol Nephrol1998，30，： | 1 |
| 14 | New insights into the origin of perylene in geological samples 显示文摘 | Grice K Lu H Atahan P Asif M Hallmann C Greenwood P Maslen E Tulipani S Williford K Dodson J | 2009 | Geochim Cosmochim Acta2009，73，21： | 1 |
| 15 | Preoperative diagnostic role of hyperbilirubinaemia as a marker of appendix perforation 显示文摘 | Atahan K Ureyen O Aslan E | 2011 | J Int MedRes2011，39，2： | 1 |
| 16 | Percent positive axillary involvement predicts for the development of brain metastasis in high- risk patients with nonmetastatic breast cancer receiving post-mastectomy radiotherapy 显示文摘 | Atahan IL Ozyigit G Yildiz F | 2008 | Breast J2008，14，3： | 1 |
| 17 | Evaluation of New Chalcone Derivatives as Polyphenol Oxidase Inhibitors显示文摘 | Sonmez F Sevmezler S Atahan A | 2011 | Bioorg Med Chem Lett2011，21，24： | 1 |
| 18 | Computer simulation of recycled content guardrail post impacts显示文摘 | Ali O Atahan Hayes E | 2004 | Journal of Transportation Engineering2004，130，6： | 1 |
| 19 | Long term outcome and prognostic factors in patients with cervical carcinoma~ a retro- spective study显示文摘 | Atahan I L Onal C Ozyar E | 2007 | Int J Gynecol Cancer2007，17，4： | 1 |
| 20 | The effect of verapamil in the prevention of radiation-induced cataract 显示文摘 | Cengiz M Gurkaynak M Atahan IL | 1999 | Int J Radiat Oncol Biol Phys1999，43，3： | 1 |
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