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| 1 | Role of triamcinolone in radiation enteritis management显示文摘AIM:To investigate the role of triamcinolone in the management of acute and chronic enteritis caused by pelvic radiotherapy.METHODS:Twenty-eight patients with rectum adenocarcinoma or endometrium adenocarcinoma were studied.We compared the results of 14 patients treated with injected triamcinolone acetonide(TA)with those of 14 patients who were not treated with TA.For the TA group,40 mg of TA was injected intramuscularly on the 1st,11th and 21st d of radiotherapy;the control group received no injections.All of the study participants had a median age of 65 years,had undergone postoperative radiotherapy and were evaluated weekly using Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer Acute Morbidity Score Criteria,and complete blood counts for every 10 d.RESULTS:Triamcinolone was found to effectively prevent and treat radiation-induced acute gastrointestinal(enteritis)and genitourinary(cystitis)side effects(P=0.022 and P=0.023).For the lower GI side effect follow up,11 patients in the control group had Grade 2toxicity and 3 patients had Grade 1 toxicity.In the TA group,5 patients had Grade 2 toxicity and 9 patients had Grade 1 toxicity.For the genitourinary system side effect follow up,4 patients had Grade 2 toxicity and 6patients had Grade 1 toxicity.Additionally,2 patients had Grade 2 toxicity and 2 patients had Grade 1 toxicity.The neutrophil counts did not differ between the TA group and the control group.There was no meaningful difference between age groups and primary cancers.At the 12th mo of follow up,there were no differences between groups for chronic side effects.CONCLUSION:Triamcinolone is a moderately potent steroid,that is inexpensive and has a good safety profile.It would be beneficial for reducing medical expenses related to treatment of radiation induced enteritis. | Eren Cetin Aysen Sevgi Ozturk Haluk Orhun Sukran Ulger | 2014 | World Journal of Gastroenterology2014，20，15： | 12 |
| 2 | Comparison of the effects of bevacizumab and ranibizumab injection on corneal angiogenesis in an alkali burn induced model显示文摘·AIM:To investigate the effects of bevacizumab and ranibizumab on corneal neovascularization in an alkali burn-induced model of corneal angiogenesis. ·METHODS:Fifteen Wistar-Albino rats were divided randomly into 3 groups after chemical cauterization of the cornea. The first group received a single dose of 0.1mL saline solution as a control group whereas second and third groups received a single dose of 2.5mg bevacizumab or 1mg ranibizumab by subconjunctival injection, respectively. After three weeks, the rat corneas were evaluated by biomicroscopy and corneal photographs were taken. The percentage of neovascularization area, length of the longest new vessel, corneal oedema and corneal opacity scores were assessed. ·RESULTS:The analysis of digital photographs showed that the percentage of neovascularization area to the total corneal area, the length of the longest new vessel, corneal oedema and opacity scores were significantly lower in both study groups compared to the control group (P <0.05). Additionally, the percentage of corneal neovascularization area, the length of the longest new vessel and corneal opacity score were less with bevacizumab than ranibizumab. ·CONCLUSION:Subconjunctival bevacizumab and ranibizumab treatments may be effective methods in reducing corneal neovascularization. Furthermore, bevacizumab is more effective than ranibizumab in the inhibition of corneal neovascularization. | Ayhan Dursun Mustafa Kemal Arici Feyza Dursun Ayse Vural Ozec Mustafa Ilker Toker Haydar Erdogan Aysen Topalkara | 2012 | International Journal of Ophthalmology(English edition)2012，5，4： | 10 |
| 3 | Co-doping of hydroxyapatite with zinc and fluoride improves mechanical and biological properties of hydroxyapatite显示文摘Hydroxyapatite(HA) co-doped with Zn2+ tand F- ions was synthesized by precipitation method for the first time in this study.FTIR spectroscopy revealed Zn2+ tand F ions incorporation into HA structure.Co-doping of Zn2+ tand F- ions decreased unit cell volume of HA and decreased grain sizes.Zn2+ tor 5 mol% F addition into HA significantly improved its density.Microhardness was increased with Zn2+ taddition and further increase was detected with F co-doping.Zn2+ tand F co-doped samples had higher fracture toughness than pure HA.Zn2+ tincorporation to the structure resulted in an increase in cell proliferation and ALP activity of cells,and further increase was observed with 1 mol%F addition.With superior mechanical properties and biological response 2Zn1 F is a good candidate for biomedical applications. | Idil Uysal Feride Severcan Aysen Tezcaner Zafer Evis | 2014 | Progress in Natural Science:Materials International2014，24，4： | 4 |
| 4 | Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma显示文摘AIM: To investigate the oxidative stress status of the aqueous humor and serum of patients with pseudoexfoliation(PEX) syndrome and pseudoexfoliative glaucoma(PEG) and to measure paraoxonase(PON) and arylesterase(ARE) levels.·METHODS: A total of 78 patients were enrolled in the study, with 26 patients in each separate group. The patients were divided into three groups: the first group entailed PEX syndrome patients, while the second group consisted of patients with PEG and the third group involved patients with no additional systemic diseases,other than the diagnosis of cataract as control. Total oxidative stress(TOS), total antioxidant capacity(TAC),PON, and ARE levels in aqueous humor and serum were measured.·RESULTS: TAC, PON and arylesterase levels in aqueous humor and serum of the PEX syndrome and PEG patients were significantly decreased compared with control group(P <0.05). TOS values were higher in patients with PEX syndrome and PEG than controls(P <0.05). TAC, PON and ARE levels of aqueous humor did not differ significantly between the PEX syndrome and PEG groups·CONCLUSION: These findings are potentially of significance and add to the growing body of evidence for oxidative stress in PEX syndrome and PEG. Decreased antioxidant defense and increased oxidative stress system may play an important role in the pathogenesis of PEX syndrome and PEG. | Feyza Dursun Ayse Vural Ozec Huseyin Aydin Aysen Topalkara Ayhan Dursun Mustafa Ilker Toker Haydar Erdogan Mustafa Kemal Arici | 2015 | International Journal of Ophthalmology(English edition)2015，8，5： | 2 |
| 5 | Evaluation of sericin/collagen membranes as prospective wound dressing biomaterial显示文摘 | Omer Akturk Aysen Tezcaner Hasan Bilgili M. Salih Deveci M. Rusen Gecit Dilek Keskin | 2011 | Journal of Bioscience and Bioengineering2011，，3： | 2 |
| 6 | Unethi- cal computer using behavior scale : A study of reliabil- ity and validity on Turkish university students 显示文摘 | Aysen Gurcan Namlu Hatice Ferhan Odabasi | 2007 | Computers & Education2007，48，2： | 1 |
| 7 | Nitrogencycling in the offshore waters of the Black Sea 显示文摘 | JAMES J M AYSEN Y COABAN-YILDIZ Y | 2007 | Estuarine Coastal and Shelf Science2007，74，3： | 1 |
| 8 | Effect of latanoprost/timolol and dorzolamide/tiomolol on intraocular pressure after phacoemulsification surgery显示文摘·AIM:To evalaute the effect of fixed-combination latanoprost 0.005%/timolol maleate 0.5% and dorzolamide hydrochloride 2%/timolol maleate 0.5% on postoperative intraocular pressure after phacoemulsification cataract surgery.·METHODS:This study is a prospective,randomized,double-masked and placebo-controlled.The study included 90 eyes of 90 patients which were scheduled to have phacoemulsification surgery.Patients were randomly assigned preoperatively to 1 of 3 groups (30 eyes of 30 patients).Two hour before surgery,the patients received one drop latanoprost/timolol (group 1),dorzolamide/timolol (group 2) and placebo (group 3,control group).The IOPs were measured at preoperative and postoperative 4,8,and 24 hours.·RESULTS:The preoperative mean intraocular pressure was not statistically significant between both drug groups and control group.In group 1 and 2,the postoperative mean IOP [group1:(14.03?à3.15)mmHg and group 2:(14.16?à4.43)mmHg] at 24 hours were significantly lower than the control group [(16.93?à3.70)mmHg,(P <0.05)].In addition,the postoperative mean IOP of group 1 [(14.90±3.69)mmHg] at 8 hours was significantly lower than the control group [(17.70?à3.89)mmHg,(P <0.05)],but there was no significant difference between group 2 [(16.16?à5.23)mmHg] and control group at 8 hours (P >0.05).·CONCLUSION:When compared with placebo,the use of preoperative fixed combination of latanoprost/timolol and dorzolamide/timolol is an effective method for preventing intraocular pressure elevation in 24 hours after phacoemulsification surgery,but did not completely prevent IOP spikes.· | Haydar Erdogan Ayse Vural Ozec Cengiz Caner Mustafa Ilker Toker Mustafa Kemal Arici Aysen Topalkara | 2011 | International Journal of Ophthalmology(English edition)2011，4，2： | 1 |
| 9 | Effect of powdered activated carbon addition on sludge dewaterability and substrate removal in landfill leachate treatment显示文摘 | Ferhan Cecen Aysen Erdincler Emel Kilic | 2003 | Advances in Environmental Research2003，7，： | 1 |
| 10 | Nitrate and pesticides removal from contaminated water using bio-denitrification reactor显示文摘 | Sukru Aslan Aysen Turkman | | 0，，04： | 1 |
| 11 | A simple tool for the assessment of water quality in polluted lagoon systems: A case study for Ktictikmece Lagoon, Turkey显示文摘 | Mehmet Umit Taner Beyza Usttin Aysen Erdincler | 2011 | Ecological Indicators2011，，： | 1 |
| 12 | Immediate postabortal contraception with the levonorgestrel intrauterine device, Norplant, and traditional methods显示文摘 | Nuriye Ortayli Aysen Bulut Tulay Sahin | 2001 | Contraception2001，63，： | 1 |
| 13 | A study of volatile organic sulfur emissions causing urban odors显示文摘 | MUEZZINOGLU AYSEN | 2003 | Chemosphere2003，51，4： | 1 |
| 14 | Analysis and Design of a Stabilized Fly Ash as Pavement Base Material显示文摘 | Hilmi Lav A Aysen Lav M Burak Goktepe A | 2006 | Fuel2006，85，16： | 1 |
| 15 | Effect of iron deficiencyanemia on the levels of hemoglobin Ale in nondiabetic patients显示文摘 | Erkan Coban Mustafa Ozdogan Aysen Timuragaoglu | 2004 | Acta Haematol2004，112，： | 1 |
| 16 | Fluoride levels in various black tea, herbal and fruit infusions consumed in Turkey 显示文摘 | Ebru Emekli-Ahurfan Aysen Yarat Serap Akyuz | 2009 | Food and Chemical Toxicology2009，47，7： | 1 |
| 17 | Biodegradation of 4-CP in an activated sludge reactor:,effects of biosurfactant and the sludge age显示文摘 | Ayla U Aysen T | 2007 | Journal of Hazardous Materials2007，148，： | 1 |
| 18 | Publications in Major Marketing Journals: An Analysi of Scholars and Marketing Departments显示文摘 | Scott J Vitell Gregory M Rose | 2000 | Journal of Marketing Education2000，22，2： | 1 |
| 19 | Co-disposal alternatives of various municipal wastewater treatment-plant sludges with refuse显示文摘 | Suna C Turgut T O Aysen E | 2004 | Advances in Environmental Research2004，，8： | 1 |
| 20 | A study of volatile organic sulfur emissions causing urban odors显示文摘 | Aysen Muezzinoglu | 2003 | Chemosphere2003，14，51： | 1 |
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