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| 1 | Exploring the role of molecular biomarkers as a potential weapon against gastric cancer: a review of the literature显示文摘Gastric cancer(GC) is a global health problem and a major cause of cancer-related death with high recurrence rates ranging from 25% to 40% for GC patients staging Ⅱ-Ⅳ. Unfortunately, while the majority of GC patients usually present with advanced tumor stage; there is still limited evidence-based therapeutic options. Current approach to GC management consists mainly of; endoscopy followed by, gastrectomy and chemotherapy or chemo-radiotherapy. Recent studies in GC have confirmed that it is a heterogeneous disease. Many molecular characterization studies have been performed in GC. Recent discoveries of the molecular pathways underlying the disease have opened the door to more personalized treatment and better predictable outcome. The identification of molecular markers is a useful tool for clinical managementin GC patients, assisting in diagnosis, evaluation of response to treatment and development of novel therapeutic modalities. While chemotherapeutic agents have certain physiological effects on the tumor cells, the prediction of the response is different from one type of tumor to the other. The specificity of molecular biomarkers is a principal feature driving their application in anticancer therapies. Here we are trying to focus on the role of molecular pathways of GC and well-established molecular markers that can guide the therapeutic management. | Marwa Matboli Sarah El-Nakeep Nourhan Hossam Alaa Habieb Ahmed EM Azazy Ali E Ebrahim Ziad Nagy Omar Abdel-Rahman | 2016 | World Journal of Gastroenterology2016，22，26： | 2 |
| 2 | Dry eye syndrome in long-term follow-up of bone marrow transplanted patients显示文摘 | Calissendorff B el Azazi M L?nnqvist B | | 0，，06： | 1 |
| 3 | T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide syn- thase gene in bladder cancer cases显示文摘 | Polat F Diler SB Azazi I | 2015 | Asian Pac J Cancer Prey2015，16，6： | 1 |
| 4 | Ophthalmological follow up of preterm infants: a population based, prospective study of visual acuity and strabismus显示文摘 | Holmstrom G Azazi M Kugelberg U | 1999 | Br J Ophthalmol1999，83，： | 1 |
| 5 | A population-based,prospective study of the development of ROP in prematurely born children in the Stockholm area of Sweden显示文摘 | Holmstr^m G el Azazi M Jacobson L | 2004 | Br J Ophthalmol2004，77，： | 1 |
| 6 | Microsurgical treatment forintramedullary spinal cord pendymomas: radical surgical resection and outcome 显示文摘 | Azazi A Sakr S Sedik M | 2011 | Neurosurg Q2011，21，2： | 1 |
| 7 | Dry eye syndrome in long- term follow-up of bone marrow transplanted patients显示文摘 | Calissendorff B el Azazi M L nnqvist B | 1989 | Bone Mar- row Transplant1989，4，6： | 1 |
| 8 | The developmentofcataraetinchildrasalateside - effectofbonemarrowtransplantation 显示文摘 | Calissendorff B Bolme P Azazi M | 1991 | Bone Marrow Tranplant1991，7，6： | 1 |
| 9 | Molecular epidemiology of Plasmodium species prevalent in Yemen based on 18S rRNA显示文摘 | A1-Mekhlafi AM Mahdy MA Azazy AA | 2010 | Parasit Vectors2010，3，： | 1 |
| 10 | Ophthalmological long term follow up of preterm infants : a population based,prospective study of the refraction and its development显示文摘 | Holmstrom M el Azazi M Kugelberg U | 1998 | Br J Ophthalmol1998，82，11： | 1 |
| 11 | Indiret haemagglutinarion (IHA)for the diagnosis of hydatid disease in Yemen 显示文摘 | Azazy AA | 2000 | J Egypt Soc Parasitology2000，30，2： | 1 |
| 12 | Sediment transport modeling for Kulim River – A case study显示文摘 | Chang Chun Kiat Aminuddin Ab Ghani Rozi Abdullah Nor Azazi Zakaria | 2008 | Journal of Hydro-environment Research2008，，1： | 1 |
| 13 | Ophthalmological long'--term follow up of preterm infants: a population based, prospective study of the refraction and its development显示文摘 | Holmstrim M Azazi M Kugelberg U | 1998 | Br J Ophthalmol1998，82，11： | 1 |
| 14 | Gross Pollutants Study in Urban Areas under Tropical Climates显示文摘 | Lariyah Mohd Sidek Hidayah Basri Mohamed Roseli Zainal Abidin Lira Chow Hock Md Nasir Md Nor Nor Azazi Zakaria | 2014 | Journal of Civil Engineering and Architecture2014，8，1： | 0 |
| 15 | 背景光强度与视网膜电图振荡电位显示文摘目的:定量分析不同强度背景光照明下,视网膜电图(electroretinogram,ERG)振荡电位(oscillatory potentials,OPs)各子波的变化,探讨背景光照明对振荡电位子波的影响.方法:记录出生25~29天Albino鼠暗视及四个不同强度背景光('弱'、'次弱'、'次强'、'强')照明下全视野ERG a波,b波和振荡电位.刺激闪光和背景照明光源均为白炽灯.刺激闪光强度1.43×102cd/m2,闪光时程75ms,闪光间隔时间1分钟;背景照明光强度1.43×10-6~1.43×100cd/m2,以二个对数单位分级.结果:振荡电位各子波在不同强度背景光照明下反应不同,'弱'背景光照明下,O1和O2振幅增高;O1振幅在'次弱'背景光照明时增高更明显;在'次强'背景光照明下,O1和O2消失,O3、O4和O5,均显著增高;当采用'强'背景光照明时,所记录的O3和O4振幅显著下降,O5振幅无变化.同时记录的ERG a波和b波在'次强'和'强'背景光照明下振幅显著降低.除O2峰时在'次弱'照明时显著延长外,其余子波在二个弱背景光照明下峰时无变化;但在二个强背景光照明下,O3、O4和O5峰时均明显缩短.结论:Albino鼠眼振荡电位各子波在不同强度背景光照明下的不同反应提示它们在视网膜的起源不同.弱背景光照明下短峰时子波活跃而强背景光照明时长峰时子波活跃,提示短峰时子波可能与暗视系统相关而长峰时子波则与明视系统相关. | 王玲 Mildred el Azazi Lillemor Wachtmeister | 2001 | 中国眼耳鼻喉科杂志2001，，6： | 0 |
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