|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Shumian capsule(舒眠胶囊) improves symptoms of sleep mood disorder in convalescent patients of Corona Virus Disease 2019显示文摘OBJECTIVE:To evaluate the clinical effectiveness of Shumian capsule(舒眠胶囊)in improving the symptoms of insomnia,anxiety,depression,and other symptoms of convalescent patients of COVID-19.METHODS:Totally 200 patients were collected and randomly divided into experiment group(n=100)and control group(n=100).The control group was treated with Shumian capsule simulator,and the experiment group was treated with Shumian capsule.The improvement of TCM symptom score,the total effective rate and symptom disappearance rate of TCM symptoms in the two groups before and after treatment were observed,and the clinical effect was evaluated.RESULTS:One week after treatment,the scores of anxiety symptoms in the experiment group were significantly different from those in the control group(P<0.05),but there was no significant difference in the scores of insomnia and depression between the experiment group and the control group(P>0.05).There was no significant difference in the total effective rate and disappearance rate of TCM symptoms of insomnia,anxiety and depression between the experiment group and the control group(P>0.05).After 2 weeks of treatment,the scores of insomnia,anxiety,depression and the total effective rate of TCM symptoms in the experiment group were significantly different from those in the control group(P<0.05).There was no significant difference in the disappearance rate of insomnia,anxiety and depression between the experiment group and the control group(P>0.05).There were no significant differences in heart rate,respiration,systolic blood pressure and diastolic blood pressure between the experiment group and the control group(P>0.05).CONCLUSION:Shumian capsule can significantly improve the symptoms of insomnia,anxiety and depression in COVID-19’s convalescent patients with sleep and mood disorders. | LI Li AN Xuedong ZHANG Qing TAO Junxiu HE Jing CHEN Yun LI Kejian LIU Ru GUO Juan ZHANG Hao TONG Xiaolin BA Yuanming | 2021 | Journal of Traditional Chinese Medicine2021，41，6： | 4 |
| 2 | Effectiveness and safety of Jinshuibao capsules(金水宝胶囊)in treatment of residual cardiopulmonary symptoms in convalescent patients of coronavirus disease 2019:a pilot randomized,double-blind,placebo-controlled clinical trial显示文摘OBJECTIVE:To evaluate the effectiveness and safety of Jinshuibao capsules(金水宝胶囊),a Traditional Chinese Medicine(TCM),in the treatment of residual cardiopulmonary symptoms in convalescent corona virus disease 2019(COVID-19)patients.METHODS:A total of 200 participants with COVID-19 in convalescence phase were randomly assigned into two groups at a 1:1 ratio in this multicenter randomized,double-blind,placebo-controlled trial.One group received Jinshuibao capsules,and the other received placebo.The patients were followed up at one and two weeks of treatment.Five symptoms(dry cough,shortness of breath,sweating,chest tightness and palpitation)improvement rates and full recovery rates were compared.RESULTS:All baseline characteristics were comparable between the two groups.After two weeks of treatment,symptom improvement rates for dry cough(74.00%vs 50.00%,P=0.015),shortness of breath(78.95%vs 46.15%,P<0.001),sweating(80.00%vs 57.75%,P=0.004),chest tightness(87.06%vs 60.47%,P<0.001)and palpitation(82.50%vs 64.56%,P=0.010)were significantly higher in the Jinshuibao group compared with the control group.Meanwhile,Jinshuibao capsules treatment also displayed more satisfactory full recovery rates of all five symptoms(dry cough 58.00%vs 19.57%,shortness of breath 18.95%vs 7.69%,sweating 36.00%vs 19.72%,chest tightness 32.94%vs 13.95%,and palpitation 48.75%vs 29.11%)in participants with COVID-19 in convalescence phase compared with the control group(P<0.05).No severe adverse events were reported in either group.CONCLUSIONS:Jinshuibao capsules have the potential to improve residual cardiopulmonary symptoms in convalescent COVID-19 patients,with few adverse events. | ZHANG Yuehong DONG Dandan YAN Youqin ZHANG Hao WANG Guangli ZHOU Wei LI Wei QIU Li LI Tingming LIU Quan XIA Ping MAO Lina YANG Danlin YANG Lu LIAN Fengmei TONG Xiaolin BA Yuanming | 2023 | Journal of Traditional Chinese Medicine2023，43，1： | 0 |
| 3 | Effectiveness of Xiangsha Liujun pills(香砂六君丸)on decreased digestive function in convalescent patients of coronavirus disease 2019:a randomized,double blind,placebo controlled clinical trial显示文摘OBJECTIVE:To evaluate the effectiveness and safety of Xiangsha Liujun pills(香砂六君丸) on the decreased digestive function in patients in the recovery phase of the Coronavirus disease 2019(COVID-19).METHODS:A randomized,double blind,placebo controlled clinical trial was conducted.A total of 200 COVID-19 patients in the recovery phase were included in our study in Ezhou Hospital of Traditional Chinese Medicine.Totally 200 subjects were randomly divided into a treatment group(Xiangsha Liujun pills) and a control group(placebo),with 100 in each group.Subjects took Xiangsha Liujun pills or placebo orally three times a day for two weeks.Three visits were scheduled at week 0(baseline),week 1(the middle of the intervention) and week 2(the end of the intervention) for each eligible patient.The total efficacy rates for improving the Traditional Chinese Medicine(TCM) symptoms(fatigue,poor appetite,abdominal distension and loose stools) and the disappearance rates of symptoms were observed and compared in the treatment and control groups.Adverse events were recorded during the study period.SAS 9.4 was used to analyze the data.RESULTS:A total of 200 patients were included in this study,among which 4 participants withdrew because the drugs did not work.Three patients were excluded for age.Before the treatment,there was no significant difference between the TCM symptoms scores of subjects.After 1 week of treatment,the full analysis set(FAS) showed that the efficacy rates for abdominal distension and loose stools in the treatment group were significantly higher than the control group(P < 0.05).There were no significant differences in the efficacy rates for fatigue and poor appetite between the two groups(P > 0.05).In addition,the disappearance rate of fatigue in the treatment group was significantly higher than the control group(P < 0.05);there were no significant differences between the two groups after treatment in the rates of poor appetite,abdominal distension,and loose stools(P > 0.05).After 2 weeks of treatment,the efficacy rates for fatigue,poor appetite,abdominal distension,and loose stools in the treatment group were significantly higher than the control group(P < 0.05).The disappearance rate of loose stools in the treatment group was significantly higher than the control group(P < 0.05).However,there were no significant differences in the disappearance rates of fatigue,poor appetite,and abdominal distension between the two groups(P > 0.05).No severe adverse events were reported by subjects during the study.CONCLUSIONS:This clinical study confirmed that Xiangsha Liujun pills can effectively improve the symptoms related to the decreased digestive function in COVID-19 convalescent patients. | ZHANG Yuehong SHAO Xianzhi ZHAO Qianlong ZHAN Hualong ZHANG Jianhua DU Sisi CHEN Jing LIU Yingfang ZHOU Haiwang CHEN Xinsheng HONG Ying LIAN Fengmei TONG Xiaolin BA Yuanming | 2023 | Journal of Traditional Chinese Medicine2023，43，3： | 0 |
| 4 | Effectiveness of Xiaoyao capsule(逍遥丸)on sleep disorders and mood disturbance in patients in recovery from coronavirus disease 2019:a randomized controlled trial显示文摘OBJECTIVE:To study the efficacy of Xiaoyao capsule(逍遥丸)in improving the clinical symptoms of sleep and mood disorders during recovery from coronavirus disease 2019(COVID-19).METHODS:The study cohort comprised 200 patients with sleep and mood disorders during recovery from COVID-19.Patients were randomized into the control group and the experimental group in a 1:1 ratio by blocked randomization.The patients received either Xiaoyao capsule(experimental group)or a placebo Xiaoyao capsule(control group)for 2 weeks.The improvements in the Traditional Chinese Medicine(TCM)syndrome scales,total effective rates,and disappearance rates of irritability,anxiety,and poor sleep were compared between the two groups.RESULTS:The TCM syndrome pattern scales,total effective rates,and disappearance rates of irritability,anxiety,and poor sleep did not significantly differ between the experimental group versus the control group in the full analysis set and the per protocol set after 1 and 2 weeks of treatment(P>0.05).CONCLUSIONS:Xiaoyao capsule do not significantly improve the clinical symptoms of sleep and mood disorders in patients in recovery from COVID-19. | YANG Cunqing LIAN Fengmei YANG Guiping HUANG Yufeng ZHANG Shuangbin WANG Jianghua ZHOU Jing GUO Dongqing SHEN Chuanyun YE Tiansong FU Aojie LI Xiaoli CHEN Le ZHANG Huifeng TU Qiyin WANG Ying YANG Wenzhe TONG Xiaolin BA Yuanming | 2023 | Journal of Traditional Chinese Medicine2023，43，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员