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259篇 您的检索式：作者名="BACH L"

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	题名	作者	年代	出处	被引量
1	PI 3-kinase pathway is responsible for antiapoptotic effects of atrial natriuretic peptide in rat liver transplantation显示文摘AIM:To investigate the in vivo effect of atrial natriureticpeptide(ANP)and its signaling pathway during ortho-topic rat liver transplantation.METHODS:Rats were infused with NaCl,ANP(5 μg/kg),wortmannin(WM,16 μg/kg),or a combination ofboth for 20 min.Livers were stored in UW solution(4°C)for 24 h,transplanted and reperfused.Apoptosis wasexamined by caspase-3 activity and TUNEL staining.Phosphorylation of Akt and Bad was visualized by West-ern blotting and phospho-Akt-localization by confocalmicroscopy.RESULTS:ANP-pretreatment decreased caspase-3activity and TUNEL-positive cells after cold ischemia,indicating antiapoptotic effects of ANP in vivo.The an-tiapoptotic signaling of ANP was most likely caused byphosphorylation of Akt and Bad,since pretreatment withPI 3-kinase inhibitor WM abrogated the ANP-inducedreduction of caspase-3 activity.Interestingly,analysis ofliver tissue by confocal microscopy showed translocationof phosphorylated Akt to the plasma membrane of hepa-tocytes evoked by ANP.CONCLUSION:ANP activates the PI-3-kinase pathwayin the liver in vivo leading to phosphorylation of Bad, an event triggering antiapoptotic signaling cascade inischemic liver.	Uwe Grutzner Melanie Keller Michael Bach Alexandra K Kiemer Herbert Meissner Manfred Bilzer Stefan Zahler Alexander L Gerbes Angelika M Vollmar	2006	World Journal of Gastroenterology2006，12，7：	3
2	Expression of Brassica juncea 3-hydroxy-3-methylglutaryl-CoA synthase is developmentally regulated and stress-responsive显示文摘	Alex D Bach T J Chye M L	2000	Plant J2000，22，5：	1
3	Elective caesarean section increases the risk of respiratory morbidity of the newborn 显示文摘	Borgwardt L Bach D Nickelsen C	2009	Acta Paediatr2009，98，1：	1
4	Tolerance to islet autoantigens in type diabetes显示文摘	Bach J F Chatenoud L	2001	Annu Rev Immunol2001，19，：	1
5	Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes显示文摘	P. V. H?jberg T. Vilsb?ll R. Rab?l F. K. Knop M. Bache T. Krarup J. J. Holst S. Madsbad	2009	Diabetologia2009，，2：	1
6	Endothelial cells and the IGF system显示文摘	BACH L A	2015	J Mol Endocrinol2015，54，1：	1
7	Systematic analysis of protein subcellular localization and interaction using high-throughput tran sient transformation of Arabidopsls seedlings显示文摘	MARION J BACH L BELLEC Y	2008	Plant Journal2008，56，1：	1
8	Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IOF-II-induced proliferation and differentiation of L6AI rat myoblasts 显示文摘	Bach L A Salerni IL Leeding K S	1995	Endocrinology1995，136，：	1
9	Optimal fund assignment and allocation models for pipe repair maintenance in leaky waterdistribution networks显示文摘	Bach N L Fujiwara O Luong H T	2000	Water Resources Reaech2000，36，5：	1
10	Detection of viable but no n-culturable Escherichia coli O157:H7 from vegetable samples using quantitative PCR with propid ium monoazide and immu nological assays显示文摘	DINU L D BACH S	2013	Food Control2013，31，2：	1
11	Heme oxygenase- 1 protects pancreatic beta cells from apoptosis caused by various stimuli显示文摘	Tobiasch E Gunther L Bach FH	2001	J lnvestig Med2001，49，8：	1
12	Influence of hydrothermal and mechanical conditions on the strength of zirconia显示文摘	Borchers L Stiesch M Bach FW	2010	Acta Bi- omater2010，6，12：	1
13	Theory of Mind: Independence of Executive Function and the Role of the Frontal Cortex in Acquired Brain Injury 显示文摘	Bach L j Happe F Fleminger S	2000	Cognitive Neuropsychiatry2000，5，3：	1
14	Chemo- sphere显示文摘	ALDER L BACHE K BECK H	1997	35(7):1391-13981997，35，7：	1
15	Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)显示文摘	Oldfield M D Bach L A Forbes J M	2001	J Clin Invest2001，108，12：	1
16	Elaboration and characterization of thin films of TiO2 prepared by sol-gel process显示文摘	Buscema C L Malibert C Bach S	2002	Thin Solid Films2002，418，：	1
17	Effects of for-age provision to young calves on rumen fermentationand development of the gastrointestinal tract显示文摘	CASTELLS L BACH A ARIS A	2013	Jour-nal of Dairy Science2013，96，8：	1
18	Chronic intermittent hypoxia elicits serotonin dependent plasticity in the central neural control of hreathing显示文摘	Ling L Fuller DD Bach KB	2001	J Neurosci2001，21，14：	1
19	Outcomes after long-term acute care:an analysis of 133 mechanically ventilated patients显示文摘	Carson S S Bach P B Brzozowski L	1999	Am J Respir Crit Care Med1999，159，51：	1
20	Expression of Brassicajuncea 3-hydroxy-3-methylglutaryl CoA synthase is developmentally regulated and stress-responsive 显示文摘	ALEX D BACH T J CHYE M L	2000	The Plant Journal2000，22，5：	1

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